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    NLN neurolysin [ Canis lupus familiaris (dog) ]

    Gene ID: 478081, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NLNprovided by VGNC
    Official Full Name
    neurolysinprovided by VGNC
    Primary source
    VGNC:VGNC:43842
    See related
    Ensembl:ENSCAFG00845010272
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See NLN in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (51935923..52030529)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (48400415..48494439)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (50676985..50771434)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (48995440..49095747)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (49784767..49878766)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene tripartite motif containing 23 Neighboring gene trafficking protein particle complex subunit 13 Neighboring gene shieldin complex subunit 3 Neighboring gene small glutamine rich tetratricopeptide repeat co-chaperone beta Neighboring gene erbb2 interacting protein Neighboring gene transcription factor BTF3 homolog 4 Neighboring gene splicing regulatory glutamic acid and lysine rich protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neurolysin, mitochondrial
    XP_005617505.1
    XP_022265685.1
    XP_022265690.1
    XP_038315633.1
    XP_038315646.1
    XP_038325848.1
    XP_038325849.1
    XP_038325850.1
    XP_038325851.1
    XP_038325852.1
    XP_038386656.1
    XP_038386657.1
    XP_038386658.1
    XP_038386659.1
    XP_038386660.1
    XP_038450880.1
    XP_038450881.1
    XP_038450882.1
    XP_038450883.1
    XP_038450884.1
    XP_038514952.1
    XP_038514953.1
    XP_038514954.1
    XP_038514955.1
    XP_038514956.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      51935923..52030529
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038659024.1 → XP_038514952.1  neurolysin, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8I3N427, A0A8I3RVP7, A0A8P0N9Z3, A0A8P0PAD1
      Related
      ENSCAFP00845014179.1, ENSCAFT00845018189.1
      Conserved Domains (1) summary
      cd06455
      Location:144 → 782
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    2. XM_038659027.1 → XP_038514955.1  neurolysin, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A8C0L949, A0A8C0LDQ9, A0A8C0PWY4, A0A8I3NF09
      Related
      ENSCAFP00845014316.1, ENSCAFT00845018341.1
      Conserved Domains (1) summary
      cd06455
      Location:57 → 695
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    3. XM_038659026.1 → XP_038514954.1  neurolysin, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LDQ9
      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    4. XM_038659025.1 → XP_038514953.1  neurolysin, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LDQ9
      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    5. XM_038659028.1 → XP_038514956.1  neurolysin, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8C0LEC6
      Conserved Domains (1) summary
      cd06455
      Location:35 → 673
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      48995440..49095747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038469920.1 → XP_038325848.1  neurolysin, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd06455
      Location:144 → 782
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    2. XM_038469923.1 → XP_038325851.1  neurolysin, mitochondrial isoform X3

      Conserved Domains (1) summary
      cd06455
      Location:57 → 695
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    3. XM_038469922.1 → XP_038325850.1  neurolysin, mitochondrial isoform X2

      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    4. XM_038469921.1 → XP_038325849.1  neurolysin, mitochondrial isoform X2

      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    5. XM_038469924.1 → XP_038325852.1  neurolysin, mitochondrial isoform X4

      Conserved Domains (1) summary
      cd06455
      Location:35 → 673
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      49784767..49878766
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038594952.1 → XP_038450880.1  neurolysin, mitochondrial isoform X1

    2. XM_038594955.1 → XP_038450883.1  neurolysin, mitochondrial isoform X3

    3. XM_038594954.1 → XP_038450882.1  neurolysin, mitochondrial isoform X2

    4. XM_038594953.1 → XP_038450881.1  neurolysin, mitochondrial isoform X2

    5. XM_038594956.1 → XP_038450884.1  neurolysin, mitochondrial isoform X4

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      50676985..50771434
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038530728.1 → XP_038386656.1  neurolysin, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8I3N427, A0A8I3RVP7, A0A8P0N9Z3, A0A8P0PAD1
      Conserved Domains (1) summary
      cd06455
      Location:144 → 782
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    2. XM_038530731.1 → XP_038386659.1  neurolysin, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A8C0L949, A0A8C0LDQ9, A0A8C0PWY4, A0A8I3NF09
      Conserved Domains (1) summary
      cd06455
      Location:57 → 695
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    3. XM_038530730.1 → XP_038386658.1  neurolysin, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LDQ9
      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    4. XM_038530729.1 → XP_038386657.1  neurolysin, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LDQ9
      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    5. XM_038530732.1 → XP_038386660.1  neurolysin, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8C0LEC6
      Conserved Domains (1) summary
      cd06455
      Location:35 → 673
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      48400415..48494439
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038459705.1 → XP_038315633.1  neurolysin, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8I3N427, A0A8I3RVP7, A0A8P0N9Z3, A0A8P0PAD1
      Conserved Domains (1) summary
      cd06455
      Location:144 → 782
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    2. XM_005617448.4 → XP_005617505.1  neurolysin, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A8C0L949, A0A8C0LDQ9, A0A8C0PWY4, A0A8I3NF09
      Conserved Domains (1) summary
      cd06455
      Location:57 → 695
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    3. XM_022409977.2 → XP_022265685.1  neurolysin, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LDQ9
      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    4. XM_022409982.2 → XP_022265690.1  neurolysin, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8C0LDQ9
      Conserved Domains (1) summary
      cd06455
      Location:60 → 698
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin

    5. XM_038459718.1 → XP_038315646.1  neurolysin, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8C0LEC6
      Conserved Domains (1) summary
      cd06455
      Location:35 → 673
      M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin
    Nucleotide Protein
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