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    AP2M1 adaptor related protein complex 2 subunit mu 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 607139, updated on 5-Mar-2024

    Summary

    Official Symbol
    AP2M1provided by VGNC
    Official Full Name
    adaptor related protein complex 2 subunit mu 1provided by VGNC
    Primary source
    VGNC:VGNC:37961
    See related
    Ensembl:ENSCAFG00845026562
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See AP2M1 in Genome Data Viewer
    Location:
    chromosome: 34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (16979339..16988512)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (21158482..21167628)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (17242835..17251997)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (17016696..17025849)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (17012627..17021768)

    Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B subunit epsilon Neighboring gene uncharacterized LOC111093832 Neighboring gene dishevelled segment polarity protein 3 Neighboring gene ATP binding cassette subfamily F member 3 Neighboring gene von Willebrand factor A domain containing 5B2 Neighboring gene ALG3 alpha-1,3- mannosyltransferase

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables clathrin adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in clathrin-dependent endocytosis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of AP-2 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-2 complex subunit mu
    Names
    adaptor related protein complex 2 mu 1 subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001287104.1NP_001274033.1  AP-2 complex subunit mu

      See identical proteins and their annotated locations for NP_001274033.1

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000363
      UniProtKB/TrEMBL
      A0A8C0JLB6, A0A8C0N3K7, A0A8I3PSX7
      Related
      ENSCAFP00845036817.1, ENSCAFT00845046933.1
      Conserved Domains (2) summary
      cd09251
      Location:168434
      AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
      cd14836
      Location:1140
      AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051838.1 Reference ROS_Cfam_1.0

      Range
      16979339..16988512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038445398.1XP_038301326.1  AP-2 complex subunit mu isoform X1

      UniProtKB/TrEMBL
      A0A8C0JLB6, A0A8C0TPE4, A0A8I3PZD2
      Related
      ENSCAFP00845036883.1, ENSCAFT00845047003.1
      Conserved Domains (2) summary
      cd09251
      Location:166432
      AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
      cd14836
      Location:1140
      AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049294.1 Alternate UMICH_Zoey_3.1

      Range
      17016696..17025849
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

      Range
      17012627..17021768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

      Range
      17242835..17251997
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      21158482..21167628
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)