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    ICA1L islet cell autoantigen 1 like [ Canis lupus familiaris (dog) ]

    Gene ID: 488479, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ICA1Lprovided by VGNC
    Official Full Name
    islet cell autoantigen 1 likeprovided by VGNC
    Primary source
    VGNC:VGNC:41855
    See related
    Ensembl:ENSCAFG00845015647
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ICA1L in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (11611993..11691866, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (12558653..12638491, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (11533517..11613396, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (11568391..11648134, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (11539667..11619487, complement)

    Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein receptor type 2 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene family with sequence similarity 117 member B Neighboring gene uncharacterized LOC102152753 Neighboring gene U4 spliceosomal RNA Neighboring gene WD repeat domain 12 Neighboring gene calcium responsive transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    islet cell autoantigen 1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051841.1 Reference ROS_Cfam_1.0

      Range
      11611993..11691866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447664.1 → XP_038303592.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_038447665.1 → XP_038303593.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    3. XM_038447666.1 → XP_038303594.1  islet cell autoantigen 1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0QTS1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 491
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_038447667.1 → XP_038303595.1  islet cell autoantigen 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0QTS1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 475
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_038447663.1 → XP_038303591.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Related
      ENSCAFP00845021966.1, ENSCAFT00845027906.1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_038447668.1 → XP_038303596.1  islet cell autoantigen 1-like protein isoform X4

      Conserved Domains (1) summary
      cl12013
      Location:57 → 198
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049297.1 Alternate UMICH_Zoey_3.1

      Range
      11568391..11648134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521720.1 → XP_038377648.1  islet cell autoantigen 1-like protein isoform X1

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_038521721.1 → XP_038377649.1  islet cell autoantigen 1-like protein isoform X1

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    3. XM_038521722.1 → XP_038377650.1  islet cell autoantigen 1-like protein isoform X2

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 491
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_038521723.1 → XP_038377651.1  islet cell autoantigen 1-like protein isoform X3

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 475
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_038521719.1 → XP_038377647.1  islet cell autoantigen 1-like protein isoform X1

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_038521725.1 → XP_038377653.1  islet cell autoantigen 1-like protein isoform X4

      Conserved Domains (1) summary
      cl12013
      Location:57 → 198
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

      Range
      11539667..11619487 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649830.1 → XP_038505758.1  islet cell autoantigen 1-like protein isoform X1

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_038649831.1 → XP_038505759.1  islet cell autoantigen 1-like protein isoform X1

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    3. XM_038649832.1 → XP_038505760.1  islet cell autoantigen 1-like protein isoform X2

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 491
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_038649833.1 → XP_038505761.1  islet cell autoantigen 1-like protein isoform X3

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 475
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_038649829.1 → XP_038505757.1  islet cell autoantigen 1-like protein isoform X1

      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_038649834.1 → XP_038505762.1  islet cell autoantigen 1-like protein isoform X4

      Conserved Domains (1) summary
      cl12013
      Location:57 → 198
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

      Range
      11533517..11613396 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038585427.1 → XP_038441355.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_038585428.1 → XP_038441356.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    3. XM_038585429.1 → XP_038441357.1  islet cell autoantigen 1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0QTS1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 491
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_038585430.1 → XP_038441358.1  islet cell autoantigen 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0QTS1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 475
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_038585426.1 → XP_038441354.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_038585431.1 → XP_038441359.1  islet cell autoantigen 1-like protein isoform X4

      Conserved Domains (1) summary
      cl12013
      Location:57 → 198
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      12558653..12638491 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014111015.3 → XP_013966490.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_038463672.1 → XP_038319600.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    3. XM_038463673.1 → XP_038319601.1  islet cell autoantigen 1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0QTS1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 491
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_038463674.1 → XP_038319602.1  islet cell autoantigen 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0QTS1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 475
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_038463671.1 → XP_038319599.1  islet cell autoantigen 1-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0QTS1, A0A8C0TTR1, A0A8I3S1M1
      Conserved Domains (2) summary
      cd07661
      Location:57 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:266 → 492
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_038463675.1 → XP_038319603.1  islet cell autoantigen 1-like protein isoform X4

      Conserved Domains (1) summary
      cl12013
      Location:57 → 198
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
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