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    PI4KA phosphatidylinositol 4-kinase alpha [ Canis lupus familiaris (dog) ]

    Gene ID: 486443, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PI4KAprovided by VGNC
    Official Full Name
    phosphatidylinositol 4-kinase alphaprovided by VGNC
    Primary source
    VGNC:VGNC:59063
    See related
    Ensembl:ENSCAFG00845025057
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    PIK4CA
    Orthologs
    human mouse all
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    Genomic context

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    See PI4KA in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    55
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (32039270..32155774)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (30589065..30707530)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (30798988..30918013)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (30085016..30204201)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (29709699..29828234)

    Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092598 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene synaptosome associated protein 29 Neighboring gene serpin family D member 1 Neighboring gene transmembrane protein 191C Neighboring gene HIC ZBTB transcriptional repressor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol 4-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 4-kinase alpha; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha
    Names
    phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
    XP_038293541.1
    XP_038368406.1
    XP_038431904.1
    XP_038496114.1
    XP_543569.7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051830.1 Reference ROS_Cfam_1.0

      Range
      32039270..32155774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038437613.1 → XP_038293541.1  phosphatidylinositol 4-kinase alpha

      UniProtKB/TrEMBL
      A0A8C0TE10
      Related
      ENSCAFP00845034705.1, ENSCAFT00845044288.1
      Conserved Domains (2) summary
      cd00871
      Location:1548 → 1723
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1784 → 2102
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049286.1 Alternate UMICH_Zoey_3.1

      Range
      30085016..30204201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038512478.1 → XP_038368406.1  phosphatidylinositol 4-kinase alpha

      Conserved Domains (2) summary
      cd00871
      Location:1548 → 1723
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1784 → 2102
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

      Range
      29709699..29828234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038640186.1 → XP_038496114.1  phosphatidylinositol 4-kinase alpha

      Conserved Domains (2) summary
      cd00871
      Location:1548 → 1723
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1784 → 2102
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

      Range
      30798988..30918013
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038575976.1 → XP_038431904.1  LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha

      UniProtKB/TrEMBL
      A0A8C0TE10
      Conserved Domains (2) summary
      cd00871
      Location:1548 → 1723
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1784 → 2102
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      30589065..30707530
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_543569.8 → XP_543569.7  phosphatidylinositol 4-kinase alpha

      UniProtKB/TrEMBL
      A0A8C0TE10
      Conserved Domains (2) summary
      cd00871
      Location:1548 → 1723
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1784 → 2102
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha
    Nucleotide Protein
    Heading Accession and Version

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