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    ACTA2 actin alpha 2, smooth muscle [ Canis lupus familiaris (dog) ]

    Gene ID: 477587, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ACTA2provided by VGNC
    Official Full Name
    actin alpha 2, smooth muscleprovided by VGNC
    Primary source
    VGNC:VGNC:37539
    See related
    Ensembl:ENSCAFG00845029801
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ACTA2 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (40285064..40299518, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (38451228..38465187, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (38990553..39005038, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (38154857..38169070, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (37720236..37734291, complement)

    Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 22 Neighboring gene STAM binding protein like 1 Neighboring gene uncharacterized LOC111092516 Neighboring gene uncharacterized LOC119866258 Neighboring gene uncharacterized LOC119866259 Neighboring gene Fas cell surface death receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immunohistochemical analysis of collagen types I, III, IV and alpha-actin in the urethra of sexually intact and ovariectomized beagles. Augsburger HR, et al. Int Urogynecol J Pelvic Floor Dysfunct, 2007 Sep. PMID 17206491

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Defining the Role of the miR-145-KLF4-alphaSMA Axis in Mitral Valvular Interstitial Cell Activation in Myxomatous Mitral Valve Prolapse Using the Canine Model.
      Title: Defining the Role of the miR-145-KLF4-αSMA Axis in Mitral Valvular Interstitial Cell Activation in Myxomatous Mitral Valve Prolapse Using the Canine Model.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    actin, aortic smooth muscle
    Names
    actin, alpha 2, smooth muscle, aorta
    smooth muscle aortic actin alpha 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051830.1 Reference ROS_Cfam_1.0

      Range
      40285064..40299518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038437710.1 → XP_038293638.1  actin, aortic smooth muscle isoform X2

      UniProtKB/TrEMBL
      A0A8C0LP85, A0A8C0RPH5, A0A8C0SW16, A0A8I3Q4M4, A0A8I3Q4N9
      Related
      ENSCAFP00845041455.1, ENSCAFT00845052808.1
      Conserved Domains (1) summary
      PTZ00281
      Location:3 → 377
      PTZ00281; actin; Provisional

    2. XM_038437709.1 → XP_038293637.1  actin, aortic smooth muscle isoform X1

      UniProtKB/TrEMBL
      A0A8I3MIB4, A0A8P0PDM2
      Conserved Domains (1) summary
      cl17037
      Location:3 → 334
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049286.1 Alternate UMICH_Zoey_3.1

      Range
      38154857..38169070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038512585.1 → XP_038368513.1  actin, aortic smooth muscle isoform X2

      Conserved Domains (1) summary
      PTZ00281
      Location:3 → 377
      PTZ00281; actin; Provisional

    2. XM_038512584.1 → XP_038368512.1  actin, aortic smooth muscle isoform X1

      Conserved Domains (1) summary
      cl17037
      Location:3 → 334
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

      Range
      37720236..37734291 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038640289.1 → XP_038496217.1  actin, aortic smooth muscle isoform X2

      Conserved Domains (1) summary
      PTZ00281
      Location:3 → 377
      PTZ00281; actin; Provisional

    2. XM_038640288.1 → XP_038496216.1  actin, aortic smooth muscle isoform X1

      Conserved Domains (1) summary
      cl17037
      Location:3 → 334
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

      Range
      38990553..39005038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038576076.1 → XP_038432004.1  actin, aortic smooth muscle isoform X2

      UniProtKB/TrEMBL
      A0A8C0LP85, A0A8C0RPH5, A0A8C0SW16, A0A8I3Q4M4, A0A8I3Q4N9
      Conserved Domains (1) summary
      PTZ00281
      Location:3 → 377
      PTZ00281; actin; Provisional

    2. XM_038576075.1 → XP_038432003.1  actin, aortic smooth muscle isoform X1

      UniProtKB/TrEMBL
      A0A8I3MIB4, A0A8P0PDM2
      Conserved Domains (1) summary
      cl17037
      Location:3 → 334
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      38451228..38465187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_534781.7 → XP_534781.2  actin, aortic smooth muscle isoform X2

      See identical proteins and their annotated locations for XP_534781.2

      UniProtKB/TrEMBL
      A0A8C0LP85, A0A8C0RPH5, A0A8C0SW16, A0A8I3Q4M4, A0A8I3Q4N9
      Conserved Domains (1) summary
      PTZ00281
      Location:3 → 377
      PTZ00281; actin; Provisional

    2. XM_038459155.1 → XP_038315083.1  actin, aortic smooth muscle isoform X1

      UniProtKB/TrEMBL
      A0A8I3MIB4, A0A8P0PDM2
      Conserved Domains (1) summary
      cl17037
      Location:3 → 334
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    Nucleotide Protein
    Heading Accession and Version

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