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    si:ch211-244o22.2 si:ch211-244o22.2 [ Danio rerio (zebrafish) ]

    Gene ID: 561487, updated on 27-Mar-2024

    Summary

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    Official Symbol
    si:ch211-244o22.2provided by ZNC
    Official Full Name
    si:ch211-244o22.2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3271
    See related
    Ensembl:ENSDARG00000068759 AllianceGenome:ZFIN:ZDB-GENE-030131-3271
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc32e05; wu:fc32e05; wu:fi04h07
    Summary
    Predicted to be involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Predicted to act upstream of or within cell division and positive regulation of protein dephosphorylation. Predicted to be active in chromosome and nucleus. Is expressed in proliferative region. Orthologous to human CDCA2 (cell division cycle associated 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (14477222..14500629, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (13977005..14000405, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 3 subunit mu 2 Neighboring gene K(lysine) acetyltransferase 6A Neighboring gene sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Neighboring gene T-box transcription factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cell division cycle-associated protein 2
    Names
    cell division cycle associated 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082823.2 → NP_001076292.1  cell division cycle-associated protein 2

      Status: VALIDATED

      Source sequence(s)
      CR392037
      UniProtKB/TrEMBL
      A0A8M1ND76, A2CEF0
      Related
      ENSDARP00000090340.2, ENSDART00000099566.4
      Conserved Domains (1) summary
      pfam15276
      Location:249 → 308
      PP1_bind; Protein phosphatase 1 binding

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      14477222..14500629 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168613.4 → XP_005168670.1  cell division cycle-associated protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A286Y9L2, A0A8M2BGI6
      Related
      ENSDARP00000143883.1, ENSDART00000176565.2
      Conserved Domains (1) summary
      pfam15276
      Location:249 → 308
      PP1_bind; Protein phosphatase 1 binding
    Nucleotide Protein Strain
    Heading Accession and Version

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