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    SGM1 Sgm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853598, updated on 13-Apr-2024

    Summary

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    Gene symbol
    SGM1
    Gene description
    Sgm1p
    Primary source
    SGD:S000003895
    Locus tag
    YJR134C
    See related
    AllianceGenome:SGD:S000003895
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in Golgi apparatus. Colocalizes with COPI-coated vesicle. Orthologous to human TMF1 (TATA element modulatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (673729..675852, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Nmd5p Neighboring gene xanthine phosphoribosyltransferase Neighboring gene Mcm22p Neighboring gene protein transporter TIM8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TMF is a golgin that binds Rab6 and influences Golgi morphology. Fridmann-Sirkis Y, et al. BMC Cell Biol, 2004 May 5. PMID 15128430, Free PMC Article
    2. Affinity purification of Ypt6 effectors and identification of TMF/ARA160 as a Rab6 interactor. Siniossoglou S. Methods Enzymol, 2005. PMID 16473623
    3. Conserved juxtamembrane domains in the yeast golgin Coy1 drive assembly of a megadalton-sized complex and mediate binding to tethering and SNARE proteins. Anderson NS, et al. J Biol Chem, 2019 Jun 21. PMID 31073031, Free PMC Article
    4. Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast. Neuber A, et al. Mol Cell Biol, 2008 Sep. PMID 18573877, Free PMC Article
    5. An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes. Siniossoglou S, et al. EMBO J, 2001 Nov 1. PMID 11689439, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Sgm1p
    NP_012668.3
    • hypothetical protein; required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      673729..675852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181792.3 → NP_012668.3  TPA: Sgm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012668.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWV2, P47166
      UniProtKB/TrEMBL
      A0A8H4BYZ7, A6ZQ89, B3LQL6, B5VLS3, C7GM79, N1P8X6
      Conserved Domains (2) summary
      TIGR02168
      Location:122 → 438
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam12325
      Location:585 → 693
      TMF_TATA_bd; TATA element modulatory factor 1 TATA binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47166.1

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