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    HAGHL hydroxyacylglutathione hydrolase like [ Canis lupus familiaris (dog) ]

    Gene ID: 490087, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HAGHLprovided by VGNC
    Official Full Name
    hydroxyacylglutathione hydrolase likeprovided by VGNC
    Primary source
    VGNC:VGNC:41586
    See related
    Ensembl:ENSCAFG00845026324
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (40197115..40200176, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (41118702..41121047, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (40324873..40327218, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (39885785..39888129, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (39845998..39848343, complement)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096335 Neighboring gene cytosolic iron-sulfur assembly component 3 Neighboring gene coiled-coil domain containing 78 Neighboring gene adenine nucleotide translocase lysine methyltransferase Neighboring gene meteorin, glial cell differentiation regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hydroxyacylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxyacylglutathione hydrolase-like protein
    NP_001191148.1
    XP_038523536.1
    XP_038523537.1
    XP_038523538.1
    XP_038523539.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204219.1 → NP_001191148.1  hydroxyacylglutathione hydrolase-like protein

      See identical proteins and their annotated locations for NP_001191148.1

      Status: VALIDATED

      Source sequence(s)
      DN392338, DN745758, JAAUVH010000065
      UniProtKB/TrEMBL
      A0A8C0K7E7, A0A8C0PXR7, A0A8C0RJD9, A0A8I3PTN8
      Related
      ENSCAFP00845036450.1, ENSCAFT00845046419.1
      Conserved Domains (1) summary
      PLN02469
      Location:1 → 257
      PLN02469; hydroxyacylglutathione hydrolase

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      40197115..40200176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038667608.1 → XP_038523536.1  hydroxyacylglutathione hydrolase-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8C0K7E7, A0A8C0PXR7, A0A8C0RJD9, A0A8I3PTN8
      Conserved Domains (1) summary
      PLN02469
      Location:1 → 257
      PLN02469; hydroxyacylglutathione hydrolase

    2. XM_038667611.1 → XP_038523539.1  hydroxyacylglutathione hydrolase-like protein isoform X4

      Conserved Domains (1) summary
      cd07723
      Location:4 → 172
      hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

    3. XM_038667609.1 → XP_038523537.1  hydroxyacylglutathione hydrolase-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0PXR7
      Conserved Domains (1) summary
      PLN02469
      Location:1 → 256
      PLN02469; hydroxyacylglutathione hydrolase

    4. XM_038667610.1 → XP_038523538.1  hydroxyacylglutathione hydrolase-like protein isoform X3

      Conserved Domains (1) summary
      cd07723
      Location:4 → 173
      hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      39885785..39888129 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      39845998..39848343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      40324873..40327218 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      41118702..41121047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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