SIX1 SIX homeobox 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: SIX1provided by VGNC
Official Full Name: SIX homeobox 1provided by VGNC
Primary source: VGNC:VGNC:46190
See related: Ensembl:ENSCAFG00845022548
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	8	NC_051812.1 (35909922..35912747, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	8	NC_006590.4 (35430686..35433517, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	8	NC_049229.1 (35960733..35963565, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	8	NC_049268.1 (35522041..35524863, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	8	NC_049749.1 (35599806..35602627, complement)

Chromosome 8 - NC_051812.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription regulator complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: homeobox protein SIX1

Names: sine oculis homeobox homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001314132.1 → NP_001301061.1 homeobox protein SIX1

Status: PROVISIONAL

Source sequence(s)

KF381338

UniProtKB/TrEMBL

A0A8C0K6U0, A0A8C0PTN2, J9P3S7

Related

ENSCAFP00845031174.1, ENSCAFT00845039804.1

Conserved Domains (2) summary

cd00086
Location:129 → 180

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

pfam16878
Location:9 → 118

SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain