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    MXD3 MAX dimerization protein 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 489093, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MXD3provided by VGNC
    Official Full Name
    MAX dimerization protein 3provided by VGNC
    Primary source
    VGNC:VGNC:51904
    See related
    Ensembl:ENSCAFG00845010663
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    MAD3
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (36409867..36417448)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (36010966..36018548)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (36930709..36938291)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (36234968..36242548)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (36421160..36428740)

    Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 14 Neighboring gene lectin, mannose binding 2 Neighboring gene PRELI domain containing 1 Neighboring gene RAB24, member RAS oncogene family Neighboring gene nuclear receptor binding SET domain protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris. Wang XH, et al. Mol Genet Genomics, 2015 Apr. PMID 25403511

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    max dimerization protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051808.1 Reference ROS_Cfam_1.0

      Range
      36409867..36417448
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038663261.1 → XP_038519189.1  max dimerization protein 3 isoform X1

      Conserved Domains (1) summary
      cl00081
      Location:143 → 212
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_038663262.1 → XP_038519190.1  max dimerization protein 3 isoform X2

      Conserved Domains (1) summary
      cl00081
      Location:71 → 140
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    3. XM_038663264.1 → XP_038519192.1  max dimerization protein 3 isoform X4

      Conserved Domains (1) summary
      cl00081
      Location:54 → 127
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    4. XM_038663263.1 → XP_038519191.1  max dimerization protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0KFM0, A0A8C0SP88, A0A8I3NFP7
      Related
      ENSCAFP00845014676.1, ENSCAFT00845018798.1
      Conserved Domains (1) summary
      cl00081
      Location:53 → 137
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_038663265.1 → XP_038519193.1  max dimerization protein 3 isoform X5

      Conserved Domains (1) summary
      cl00081
      Location:41 → 123
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049264.1 Alternate UMICH_Zoey_3.1

      Range
      36234968..36242548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038473581.1 → XP_038329509.1  max dimerization protein 3 isoform X1

      Conserved Domains (1) summary
      cl00081
      Location:143 → 212
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_038473582.1 → XP_038329510.1  max dimerization protein 3 isoform X2

      Conserved Domains (1) summary
      cl00081
      Location:71 → 140
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    3. XM_038473584.1 → XP_038329512.1  max dimerization protein 3 isoform X4

      Conserved Domains (1) summary
      cl00081
      Location:54 → 127
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    4. XM_038473583.1 → XP_038329511.1  max dimerization protein 3 isoform X3

      Conserved Domains (1) summary
      cl00081
      Location:53 → 137
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_038473585.1 → XP_038329513.1  max dimerization protein 3 isoform X5

      Conserved Domains (1) summary
      cl00081
      Location:41 → 123
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

      Range
      36421160..36428740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038598958.1 → XP_038454886.1  max dimerization protein 3 isoform X1

      Conserved Domains (1) summary
      cl00081
      Location:143 → 212
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_038598959.1 → XP_038454887.1  max dimerization protein 3 isoform X2

      Conserved Domains (1) summary
      cl00081
      Location:71 → 140
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    3. XM_038598961.1 → XP_038454889.1  max dimerization protein 3 isoform X4

      Conserved Domains (1) summary
      cl00081
      Location:54 → 127
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    4. XM_038598960.1 → XP_038454888.1  max dimerization protein 3 isoform X3

      Conserved Domains (1) summary
      cl00081
      Location:53 → 137
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_038598962.1 → XP_038454890.1  max dimerization protein 3 isoform X5

      Conserved Domains (1) summary
      cl00081
      Location:41 → 123
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

      Range
      36930709..36938291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038534654.1 → XP_038390582.1  max dimerization protein 3 isoform X1

      Conserved Domains (1) summary
      cl00081
      Location:143 → 212
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_038534655.1 → XP_038390583.1  max dimerization protein 3 isoform X2

      Conserved Domains (1) summary
      cl00081
      Location:71 → 140
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    3. XM_038534657.1 → XP_038390585.1  max dimerization protein 3 isoform X4

      Conserved Domains (1) summary
      cl00081
      Location:54 → 127
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    4. XM_038534656.1 → XP_038390584.1  max dimerization protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0KFM0, A0A8C0SP88, A0A8I3NFP7
      Conserved Domains (1) summary
      cl00081
      Location:53 → 137
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_038534658.1 → XP_038390586.1  max dimerization protein 3 isoform X5

      Conserved Domains (1) summary
      cl00081
      Location:41 → 123
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      36010966..36018548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022417661.2 → XP_022273369.1  max dimerization protein 3 isoform X1

      Conserved Domains (1) summary
      cl00081
      Location:143 → 212
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. XM_038494060.1 → XP_038349988.1  max dimerization protein 3 isoform X2

      Conserved Domains (1) summary
      cl00081
      Location:71 → 140
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    3. XM_038494063.1 → XP_038349991.1  max dimerization protein 3 isoform X4

      Conserved Domains (1) summary
      cl00081
      Location:54 → 127
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    4. XM_546209.7 → XP_546209.2  max dimerization protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0KFM0, A0A8C0SP88, A0A8I3NFP7
      Conserved Domains (1) summary
      cl00081
      Location:53 → 137
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_038494064.1 → XP_038349992.1  max dimerization protein 3 isoform X5

      Conserved Domains (1) summary
      cl00081
      Location:41 → 123
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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