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Skin infection

MedGen UID:
52365
•Concept ID:
C0037278
•
Disease or Syndrome
Synonyms: Disease, Infectious Skin; Diseases, Infectious Skin; Infectious Skin Disease; Infectious Skin Diseases; Skin Disease, Infectious; Skin Diseases, Infectious
SNOMED CT: Infection of skin (108365000)
 
Monarch Initiative: MONDO:0021201

Definition

An inflammatory process affecting the skin, caused by bacteria, viruses, parasites, or fungi. Examples of bacterial infection include carbuncles, furuncles, impetigo, erysipelas, and abscesses. Examples of viral infection include shingles, warts, molluscum contagiosum, and pityriasis rosea. Examples of parasitic infection include scabies and lice. Examples of fungal infection include athlete''s foot, yeast infection, and ringworm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin infection

Professional guidelines

PubMed

Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Methicillin-Resistant Staphylococcus aureus Infection and Treatment Options.
Chalmers SJ, Wylam ME
Methods Mol Biol 2020;2069:229-251. doi: 10.1007/978-1-4939-9849-4_16. PMID: 31523777
Impetigo: diagnosis and treatment.
Hartman-Adams H, Banvard C, Juckett G
Am Fam Physician 2014 Aug 15;90(4):229-35. PMID: 25250996

Recent clinical studies

Etiology

Mycobacterial skin infection.
Gardini G, Gregori N, Matteelli A, Castelli F
Curr Opin Infect Dis 2022 Apr 1;35(2):79-87. doi: 10.1097/QCO.0000000000000820. PMID: 35067521Free PMC Article
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771
Maternal obesity and pregnancy.
Satpathy HK, Fleming A, Frey D, Barsoom M, Satpathy C, Khandalavala J
Postgrad Med 2008 Sep 15;120(3):E01-9. doi: 10.3810/pgm.2008.09.1920. PMID: 18824817

Diagnosis

Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Medical Complications of Tattoos: A Comprehensive Review.
Islam PS, Chang C, Selmi C, Generali E, Huntley A, Teuber SS, Gershwin ME
Clin Rev Allergy Immunol 2016 Apr;50(2):273-86. doi: 10.1007/s12016-016-8532-0. PMID: 26940693
Impetigo: diagnosis and treatment.
Hartman-Adams H, Banvard C, Juckett G
Am Fam Physician 2014 Aug 15;90(4):229-35. PMID: 25250996
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771

Therapy

Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Medical Complications of Tattoos: A Comprehensive Review.
Islam PS, Chang C, Selmi C, Generali E, Huntley A, Teuber SS, Gershwin ME
Clin Rev Allergy Immunol 2016 Apr;50(2):273-86. doi: 10.1007/s12016-016-8532-0. PMID: 26940693
Common Skin Rashes in Children.
Allmon A, Deane K, Martin KL
Am Fam Physician 2015 Aug 1;92(3):211-6. PMID: 26280141
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.
Beck LA, Thaçi D, Hamilton JD, Graham NM, Bieber T, Rocklin R, Ming JE, Ren H, Kao R, Simpson E, Ardeleanu M, Weinstein SP, Pirozzi G, Guttman-Yassky E, Suárez-Fariñas M, Hager MD, Stahl N, Yancopoulos GD, Radin AR
N Engl J Med 2014 Jul 10;371(2):130-9. doi: 10.1056/NEJMoa1314768. PMID: 25006719
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771

Prognosis

Review: Emergomycosis.
Reddy DL, Nel J, Govender NP
J Mycol Med 2023 Mar;33(1):101313. Epub 2022 Jul 23 doi: 10.1016/j.mycmed.2022.101313. PMID: 36272380
Septic Arthritis: Diagnosis and Treatment.
Earwood JS, Walker TR, Sue GJC
Am Fam Physician 2021 Dec 1;104(6):589-597. PMID: 34913662
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Common Skin Rashes in Children.
Allmon A, Deane K, Martin KL
Am Fam Physician 2015 Aug 1;92(3):211-6. PMID: 26280141
Impetigo: diagnosis and treatment.
Hartman-Adams H, Banvard C, Juckett G
Am Fam Physician 2014 Aug 15;90(4):229-35. PMID: 25250996

Clinical prediction guides

Comparing four immunosuppressive agents for chronic spontaneous urticaria-A network meta-analysis.
Bei W, Qian J, Zilu Q, Kai C, Ruili J, Feng H, Liuqing C
Int Immunopharmacol 2023 Oct;123:110577. Epub 2023 Aug 9 doi: 10.1016/j.intimp.2023.110577. PMID: 37567010
Latest Advances in the Application of Humanized Mouse Model for Staphylococcus aureus.
Zheng P, Liu F, Long J, Jin Y, Chen S, Duan G, Yang H
J Infect Dis 2023 Sep 15;228(6):800-809. doi: 10.1093/infdis/jiad253. PMID: 37392466
Omadacycline in Skin Infections and Pneumonia: A Review of the Evidence.
Vacalis S, Brunton S, Gindi J
J Fam Pract 2022 Jun;71(5 Suppl):S10-S21. doi: 10.12788/jfp.0424. PMID: 35776862
Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.
Beck LA, Thaçi D, Hamilton JD, Graham NM, Bieber T, Rocklin R, Ming JE, Ren H, Kao R, Simpson E, Ardeleanu M, Weinstein SP, Pirozzi G, Guttman-Yassky E, Suárez-Fariñas M, Hager MD, Stahl N, Yancopoulos GD, Radin AR
N Engl J Med 2014 Jul 10;371(2):130-9. doi: 10.1056/NEJMoa1314768. PMID: 25006719

Recent systematic reviews

Ceftaroline: Systematic Review of Clinical Uses and Emerging Drug Resistance.
Abate G, Wang G, Frisby J
Ann Pharmacother 2022 Dec;56(12):1339-1348. Epub 2022 Mar 18 doi: 10.1177/10600280221082326. PMID: 35300514
American Academy of Dermatology Guidelines: Awareness of comorbidities associated with atopic dermatitis in adults.
Davis DMR, Drucker AM, Alikhan A, Bercovitch L, Cohen DE, Darr JM, Eichenfield LF, Frazer-Green L, Paller AS, Silverberg JI, Singh AM, Sidbury R
J Am Acad Dermatol 2022 Jun;86(6):1335-1336.e18. Epub 2022 Jan 24 doi: 10.1016/j.jaad.2022.01.009. PMID: 35085682
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Cro S, Cornelius V, Lodrup Carlsen KC, Skjerven HO, Rehbinder EM, Lowe AJ, Dissanayake E, Shimojo N, Yonezawa K, Ohya Y, Yamamoto-Hanada K, Morita K, Axon E, Surber C, Cork M, Cooke A, Tran L, Van Vogt E, Schmitt J, Weidinger S, McClanahan D, Simpson E, Duley L, Askie LM, Chalmers JR, Williams HC, Boyle RJ
Cochrane Database Syst Rev 2021 Feb 5;2(2):CD013534. doi: 10.1002/14651858.CD013534.pub2. PMID: 33545739Free PMC Article
Early diagnosis of necrotizing fasciitis.
Goh T, Goh LG, Ang CH, Wong CH
Br J Surg 2014 Jan;101(1):e119-25. Epub 2013 Nov 29 doi: 10.1002/bjs.9371. PMID: 24338771
Evidence-based diagnostics: adult septic arthritis.
Carpenter CR, Schuur JD, Everett WW, Pines JM
Acad Emerg Med 2011 Aug;18(8):781-96. doi: 10.1111/j.1553-2712.2011.01121.x. PMID: 21843213Free PMC Article

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