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DDR1 kinase autoinhibited by its juxtamembrane region[TRANSFERASE]
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor[TRANSFERASE]
DDR1 bound to Dasatinib[TRANSFERASE/TRANSFERASE INHIBITOR]
View in iCn3D Similar StructuresPubMedProteinsPubChem Compound
DDR1 bound to VX-680[TRANSFERASE/TRANSFERASE INHIBITOR]
DDR1, 1-(1H-indazole-5-carbonyl)-5'-methoxy-1'-[2-oxo-2-[(2S)-2-(trifluoromethyl)pyrrolidin-1-yl]ethyl]spiro[piperidine-4,3'-pyrrolo[3,2-b]pyridine]-2'-one, 1.790A, P212121, Rfree=23.8%[TRANSFERASE]
DDR1, 2-[1'-(1H-indazole-5-carbonyl)-4-methyl-2-oxospiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide, 1.990A, P6522, Rfree=27.7%[TRANSFERASE]
DDR1, 3-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(1H-indazole-5-carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 1.670A, P1211, Rfree=22.8%[TRANSFERASE]
DDR1, 2-[8-(1H-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]-N-methylacetamide, 1.730A, P212121, Rfree=24.5%[TRANSFERASE]
DDR1, 2-[4-bromo-2-oxo-1'-(1H-pyrazolo[4,3-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide, 1.291A, P212121, Rfree=17.4%[TRANSFERASE]
DDR1, 2-[8-(1H-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]-N-methylacetamide, 1.440A, P1211, Rfree=24.1%[TRANSFERASE]
Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution[TRANSFERASE]
View in iCn3D Similar StructuresProteinsConserved DomainsPubChem Compound
Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution[TRANSFERASE]
Fragment-based Discovery Of Potent And Selective Ddr1/2 Inhibitors[Transferase, EC: 2.7.10.1]
Crystal structure of the human DDR1 kinase domain in complex with DDR1-IN-1[TRANSFERASE]
Crystal structure of the human DDR1 kinase domain in complex with imatinib[TRANSFERASE]
Structure of the DDR1 kinase domain in complex with ponatinib[TRANSFERASE]
Crystal structure of a DDR1-Fab complex[IMMUNE SYSTEM/TRANSFERASE]
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