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    SEPTIN4 septin 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 480571, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SEPTIN4provided by VGNC
    Official Full Name
    septin 4provided by VGNC
    Primary source
    VGNC:VGNC:55818
    See related
    Ensembl:ENSCAFG00845021290
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    SEPT4
    Orthologs
    human mouse all
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    Genomic context

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    See SEPTIN4 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (33944231..33967292, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (32373320..32397361, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (33106394..33130433, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (32730857..32754884, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (33014223..33038236, complement)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor 5 Neighboring gene uncharacterized LOC111097407 Neighboring gene myotubularin related protein 4 Neighboring gene uncharacterized LOC106559302 Neighboring gene testis expressed 14, intercellular bridge forming factor Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC111097408 Neighboring gene small nucleolar RNA U3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton-dependent cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell division site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of septin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in septin ring IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in sperm annulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    septin-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      33944231..33967292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038677100.1 → XP_038533028.1  septin-4 isoform X8

      UniProtKB/TrEMBL
      A0A8P0SLS4
      Conserved Domains (2) summary
      pfam00735
      Location:548 → 820
      Septin
      pfam15548
      Location:1 → 423
      DUF4655; Domain of unknown function (DUF4655)

    2. XM_038677103.1 → XP_038533031.1  septin-4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MHZ8, A0A8I3PD80
      Conserved Domains (1) summary
      pfam00735
      Location:134 → 406
      Septin

    3. XM_038677102.1 → XP_038533030.1  septin-4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MHZ8, A0A8I3PD80
      Conserved Domains (2) summary
      pfam00735
      Location:141 → 413
      Septin
      pfam15548
      Location:3 → 16
      DUF4655; Domain of unknown function (DUF4655)

    4. XM_038677106.1 → XP_038533034.1  septin-4 isoform X6

      UniProtKB/TrEMBL
      A0A8C0LPT8
      Conserved Domains (1) summary
      pfam00735
      Location:24 → 296
      Septin

    5. XM_038677104.1 → XP_038533032.1  septin-4 isoform X4

      UniProtKB/TrEMBL
      A0A5F4C7B5, A0A8C0RUQ8, A0A8I3PCP9, A0A8P0T3Y3
      Related
      ENSCAFP00845029814.1, ENSCAFT00845038052.1
      Conserved Domains (1) summary
      pfam00735
      Location:122 → 394
      Septin

    6. XM_038677101.1 → XP_038533029.1  septin-4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LR05, A0A8C0PUI1
      Related
      ENSCAFP00845029878.1, ENSCAFT00845038143.1
      Conserved Domains (1) summary
      pfam00735
      Location:141 → 413
      Septin

    7. XM_038677105.1 → XP_038533033.1  septin-4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0LPT8, A0A8C0MRS7, A0A8I3S4Y9
      Related
      ENSCAFP00845029602.1, ENSCAFT00845037779.1
      Conserved Domains (1) summary
      pfam00735
      Location:43 → 315
      Septin

    8. XM_038677107.1 → XP_038533035.1  septin-4 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LPT8, A0A8C0PPY1
      Conserved Domains (1) summary
      pfam00735
      Location:1 → 267
      Septin

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      32730857..32754884 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038486099.1 → XP_038342027.1  septin-4 isoform X10

    2. XM_038486098.1 → XP_038342026.1  septin-4 isoform X9

    3. XM_038486108.1 → XP_038342036.1  septin-4 isoform X3

      Conserved Domains (1) summary
      pfam00735
      Location:134 → 406
      Septin

    4. XM_038486107.1 → XP_038342035.1  septin-4 isoform X2

      Conserved Domains (2) summary
      pfam00735
      Location:141 → 413
      Septin
      pfam15548
      Location:3 → 16
      DUF4655; Domain of unknown function (DUF4655)

    5. XM_038486111.1 → XP_038342039.1  septin-4 isoform X6

      Conserved Domains (1) summary
      pfam00735
      Location:24 → 296
      Septin

    6. XM_038486109.1 → XP_038342037.1  septin-4 isoform X4

      Conserved Domains (1) summary
      pfam00735
      Location:122 → 394
      Septin

    7. XM_038486106.1 → XP_038342034.1  septin-4 isoform X1

      Conserved Domains (1) summary
      pfam00735
      Location:141 → 413
      Septin

    8. XM_038486110.1 → XP_038342038.1  septin-4 isoform X5

      Conserved Domains (1) summary
      pfam00735
      Location:43 → 315
      Septin

    9. XM_038486112.1 → XP_038342040.1  septin-4 isoform X7

      Conserved Domains (1) summary
      pfam00735
      Location:1 → 267
      Septin

    10. XM_038486105.1 → XP_038342033.1  septin-4 isoform X15

    11. XM_038486101.1 → XP_038342029.1  septin-4 isoform X12

    12. XM_038486102.1 → XP_038342030.1  septin-4 isoform X12

    13. XM_038486104.1 → XP_038342032.1  septin-4 isoform X14

    14. XM_038486100.1 → XP_038342028.1  septin-4 isoform X11

    15. XM_038486103.1 → XP_038342031.1  septin-4 isoform X13

    RNA

    1. XR_005330902.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      33014223..33038236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038611876.1 → XP_038467804.1  septin-4 isoform X17

    2. XM_038611875.1 → XP_038467803.1  septin-4 isoform X16

    3. XM_038611885.1 → XP_038467813.1  septin-4 isoform X3

      Conserved Domains (1) summary
      pfam00735
      Location:134 → 406
      Septin

    4. XM_038611884.1 → XP_038467812.1  septin-4 isoform X2

      Conserved Domains (2) summary
      pfam00735
      Location:141 → 413
      Septin
      pfam15548
      Location:3 → 16
      DUF4655; Domain of unknown function (DUF4655)

    5. XM_038611888.1 → XP_038467816.1  septin-4 isoform X6

      Conserved Domains (1) summary
      pfam00735
      Location:24 → 296
      Septin

    6. XM_038611886.1 → XP_038467814.1  septin-4 isoform X4

      Conserved Domains (1) summary
      pfam00735
      Location:122 → 394
      Septin

    7. XM_038611883.1 → XP_038467811.1  septin-4 isoform X1

      Conserved Domains (1) summary
      pfam00735
      Location:141 → 413
      Septin

    8. XM_038611887.1 → XP_038467815.1  septin-4 isoform X5

      Conserved Domains (1) summary
      pfam00735
      Location:43 → 315
      Septin

    9. XM_038611889.1 → XP_038467817.1  septin-4 isoform X7

      Conserved Domains (1) summary
      pfam00735
      Location:1 → 267
      Septin

    10. XM_038611882.1 → XP_038467810.1  septin-4 isoform X22

    11. XM_038611878.1 → XP_038467806.1  septin-4 isoform X19

    12. XM_038611879.1 → XP_038467807.1  septin-4 isoform X19

    13. XM_038611881.1 → XP_038467809.1  septin-4 isoform X21

    14. XM_038611877.1 → XP_038467805.1  septin-4 isoform X18

    15. XM_038611880.1 → XP_038467808.1  septin-4 isoform X20

    RNA

    1. XR_005399032.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      33106394..33130433 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038547898.1 → XP_038403826.1  septin-4 isoform X24

      UniProtKB/TrEMBL
      A0A8P0SLS4

    2. XM_038547897.1 → XP_038403825.1  septin-4 isoform X23

      UniProtKB/TrEMBL
      A0A8P0SLS4

    3. XM_038547907.1 → XP_038403835.1  septin-4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MHZ8, A0A8I3PD80

    4. XM_038547906.1 → XP_038403834.1  septin-4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MHZ8, A0A8I3PD80

    5. XM_038547910.1 → XP_038403838.1  septin-4 isoform X6

      UniProtKB/TrEMBL
      A0A8C0LPT8

    6. XM_038547908.1 → XP_038403836.1  septin-4 isoform X4

      UniProtKB/TrEMBL
      A0A8I3PCP9, A0A8P0T3Y3

    7. XM_038547905.1 → XP_038403833.1  septin-4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LR05

    8. XM_038547909.1 → XP_038403837.1  septin-4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0LPT8

    9. XM_038547911.1 → XP_038403839.1  septin-4 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LPT8

    10. XM_038547904.1 → XP_038403832.1  septin-4 isoform X29

      UniProtKB/TrEMBL
      A0A8C0LNX7

    11. XM_038547900.1 → XP_038403828.1  septin-4 isoform X26

      UniProtKB/TrEMBL
      A0A8C0LNX7

    12. XM_038547901.1 → XP_038403829.1  septin-4 isoform X26

      UniProtKB/TrEMBL
      A0A8C0LNX7

    13. XM_038547903.1 → XP_038403831.1  septin-4 isoform X28

      UniProtKB/TrEMBL
      A0A8C0LNX7

    14. XM_038547899.1 → XP_038403827.1  septin-4 isoform X25

      UniProtKB/TrEMBL
      A0A8C0LNX7

    15. XM_038547902.1 → XP_038403830.1  septin-4 isoform X27

      UniProtKB/TrEMBL
      A0A8C0LNX7

    RNA

    1. XR_005364594.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      32373320..32397361 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022423199.2 → XP_022278907.1  septin-4 isoform X31

      UniProtKB/TrEMBL
      A0A8P0SLS4
      Conserved Domains (2) summary
      pfam00735
      Location:677 → 949
      Septin
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    2. XM_003435278.5 → XP_003435326.3  septin-4 isoform X30

      UniProtKB/TrEMBL
      A0A8P0SLS4
      Conserved Domains (2) summary
      pfam00735
      Location:677 → 949
      Septin; Septin
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    3. XM_022423207.2 → XP_022278915.1  septin-4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MHZ8, A0A8I3PD80
      Conserved Domains (1) summary
      pfam00735
      Location:134 → 406
      Septin

    4. XM_022423206.1 → XP_022278914.1  septin-4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MHZ8, A0A8I3PD80
      Conserved Domains (2) summary
      pfam00735
      Location:141 → 413
      Septin
      pfam15548
      Location:3 → 16
      DUF4655; Domain of unknown function (DUF4655)

    5. XM_005624729.4 → XP_005624786.1  septin-4 isoform X6

      UniProtKB/TrEMBL
      A0A8C0LPT8
      Conserved Domains (1) summary
      pfam00735
      Location:24 → 296
      Septin

    6. XM_537693.7 → XP_537693.3  septin-4 isoform X4

      UniProtKB/TrEMBL
      A0A5F4C7B5, A0A8C0RUQ8, A0A8I3PCP9, A0A8P0T3Y3
      Conserved Domains (1) summary
      pfam00735
      Location:122 → 394
      Septin

    7. XM_861979.6 → XP_867072.3  septin-4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LR05, A0A8C0PUI1
      Conserved Domains (1) summary
      pfam00735
      Location:141 → 413
      Septin

    8. XM_005624727.3 → XP_005624784.2  septin-4 isoform X5

      UniProtKB/TrEMBL
      A0A8C0LPT8, A0A8C0MRS7, A0A8I3S4Y9
      Conserved Domains (1) summary
      pfam00735
      Location:43 → 315
      Septin

    9. XM_005624730.3 → XP_005624787.1  septin-4 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LPT8, A0A8C0PPY1
      Conserved Domains (1) summary
      pfam00735
      Location:1 → 267
      Septin

    10. XM_014116705.3 → XP_013972180.1  septin-4 isoform X36

      UniProtKB/TrEMBL
      A0A8C0LNX7
      Conserved Domains (1) summary
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    11. XM_022423201.2 → XP_022278909.1  septin-4 isoform X33

      UniProtKB/TrEMBL
      A0A8C0LNX7
      Conserved Domains (1) summary
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    12. XM_022423203.2 → XP_022278911.1  septin-4 isoform X33

      UniProtKB/TrEMBL
      A0A8C0LNX7
      Conserved Domains (1) summary
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    13. XM_022423205.2 → XP_022278913.1  septin-4 isoform X35

      UniProtKB/TrEMBL
      A0A8C0LNX7
      Conserved Domains (1) summary
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    14. XM_022423200.2 → XP_022278908.1  septin-4 isoform X32

      UniProtKB/TrEMBL
      A0A8C0LNX7
      Conserved Domains (1) summary
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    15. XM_022423204.2 → XP_022278912.1  septin-4 isoform X34

      UniProtKB/TrEMBL
      A0A8C0LNX7
      Conserved Domains (1) summary
      pfam15548
      Location:13 → 552
      DUF4655; Domain of unknown function (DUF4655)

    RNA

    1. XR_002630037.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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