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    LOC106154118 neurogenic locus notch homolog protein 1 [ Lingula anatina ]

    Gene ID: 106154118, updated on 21-Dec-2023

    Summary

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    Gene symbol
    LOC106154118
    Gene description
    neurogenic locus notch homolog protein 1
    See related
    EnsemblRapid:LOC106154118
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lingula anatina
    Lineage
    Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Brachiopoda; Linguliformea; Lingulata; Lingulida; Linguloidea; Lingulidae; Lingula
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    101 current LinAna2.0 (GCF_001039355.2) Unplaced Scaffold NW_019776142.1 (74496..100074, complement)
    100 previous assembly LinAna1.0 (GCF_001039355.1) Unplaced Scaffold NW_013577554.1 (74496..100038, complement)

    NW_019776142.1Genomic Context describing neighboring genes Neighboring gene regulatory-associated protein of mTOR-like Neighboring gene flocculation protein FLO11 Neighboring gene transfer RNA tryptophan (anticodon CCA)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Lingula genome provides insights into brachiopod evolution and the origin of phosphate biomineralization. Luo YJ, et al. Nat Commun, 2015 Sep 18. PMID 26383154, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neurogenic locus notch homolog protein 1; neurogenic locus notch homolog protein 2; uncharacterized protein LOC106154118

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Lingula anatina Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference LinAna2.0 Primary Assembly

    Genomic

    1. NW_019776142.1 Reference LinAna2.0 Primary Assembly

      Range
      74496..100074 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024074699.1 → XP_023930467.1  neurogenic locus notch homolog protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A2R2MJS0
      Related
      XP_023930467.1, XM_024074699.1
      Conserved Domains (7) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1830 → 1864
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00008
      Location:1514 → 1544
      EGF; EGF-like domain
      pfam16489
      Location:2053 → 2251
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd15040
      Location:2330 → 2589
      7tmB2_Adhesion; adhesion receptors, subfamily B2 of the class B family of seven-transmembrane G protein-coupled receptors
      cl02559
      Location:2275 → 2320
      GPS; GPCR proteolysis site, GPS, motif

    2. XM_024074698.1 → XP_023930466.1  neurogenic locus notch homolog protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A2R2MJS0
      Related
      XP_023930466.1, XM_024074698.1
      Conserved Domains (7) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1830 → 1864
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00008
      Location:1514 → 1544
      EGF; EGF-like domain
      pfam16489
      Location:2053 → 2251
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd15040
      Location:2330 → 2589
      7tmB2_Adhesion; adhesion receptors, subfamily B2 of the class B family of seven-transmembrane G protein-coupled receptors
      cl02559
      Location:2275 → 2320
      GPS; GPCR proteolysis site, GPS, motif

    3. XM_024074700.1 → XP_023930468.1  neurogenic locus notch homolog protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A2R2MJU4
      Related
      XP_023930468.1, XM_024074700.1
      Conserved Domains (7) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1830 → 1864
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00008
      Location:1514 → 1544
      EGF; EGF-like domain
      pfam16489
      Location:1974 → 2172
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd15040
      Location:2251 → 2510
      7tmB2_Adhesion; adhesion receptors, subfamily B2 of the class B family of seven-transmembrane G protein-coupled receptors
      cl02559
      Location:2196 → 2241
      GPS; GPCR proteolysis site, GPS, motif

    4. XM_024074697.1 → XP_023930465.1  neurogenic locus notch homolog protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A2R2MJS0
      Related
      XP_023930465.1, XM_024074697.1
      Conserved Domains (7) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1830 → 1864
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00008
      Location:1514 → 1544
      EGF; EGF-like domain
      pfam16489
      Location:2053 → 2251
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd15040
      Location:2330 → 2589
      7tmB2_Adhesion; adhesion receptors, subfamily B2 of the class B family of seven-transmembrane G protein-coupled receptors
      cl02559
      Location:2275 → 2320
      GPS; GPCR proteolysis site, GPS, motif

    5. XM_013528375.1 → XP_013383829.1  neurogenic locus notch homolog protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A1S3HFL8
      Related
      XP_013383829.1, XM_013528375.1
      Conserved Domains (8) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      COG0842
      Location:2253 → 2407
      YadH; ABC-type multidrug transport system, permease component [Defense mechanisms]
      cd00054
      Location:1660 → 1694
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00008
      Location:1344 → 1374
      EGF; EGF-like domain
      pfam01825
      Location:2104 → 2144
      GPS; GPCR proteolysis site, GPS, motif
      pfam16489
      Location:1884 → 2085
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cl21561
      Location:2160 → 2404
      7tm_4; Olfactory receptor

    6. XM_024074701.1 → XP_023930469.1  neurogenic locus notch homolog protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A2R2MJS8
      Related
      XP_023930469.1, XM_024074701.1
      Conserved Domains (7) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1548 → 1582
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00008
      Location:1232 → 1262
      EGF; EGF-like domain
      pfam16489
      Location:1771 → 1969
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd15040
      Location:2048 → 2307
      7tmB2_Adhesion; adhesion receptors, subfamily B2 of the class B family of seven-transmembrane G protein-coupled receptors
      cl02559
      Location:1993 → 2038
      GPS; GPCR proteolysis site, GPS, motif

    7. XM_024074702.1 → XP_023930470.1  uncharacterized protein LOC106154118 isoform X5

      UniProtKB/TrEMBL
      A0A2R2MJT5
      Related
      XP_023930470.1, XM_024074702.1
      Conserved Domains (6) summary
      cd11304
      Location:145 → 239
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1012 → 1048
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:243 → 337
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam16489
      Location:1120 → 1318
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd15040
      Location:1397 → 1656
      7tmB2_Adhesion; adhesion receptors, subfamily B2 of the class B family of seven-transmembrane G protein-coupled receptors
      cl02559
      Location:1342 → 1387
      GPS; GPCR proteolysis site, GPS, motif
    Nucleotide Protein
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