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    NEIL3 nei like DNA glycosylase 3 [ Bos taurus (cattle) ]

    Gene ID: 515343, updated on 5-Mar-2024

    Summary

    Official Symbol
    NEIL3provided by VGNC
    Official Full Name
    nei like DNA glycosylase 3provided by VGNC
    Primary source
    VGNC:VGNC:31990
    See related
    BGD:BT14061; Ensembl:ENSBTAG00000005825
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    Location:
    chromosome: 27
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 27 NC_037354.1 (8574871..8621182)

    Chromosome 27 - NC_037354.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit C-like Neighboring gene uncharacterized LOC112444624 Neighboring gene uncharacterized LOC101904157 Neighboring gene aspartylglucosaminidase Neighboring gene uncharacterized LOC132344088

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Clone Names

    • MGC127868

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in base-excision repair IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    endonuclease 8-like 3
    Names
    DNA glycosylase/AP lyase Neil3
    endonuclease VIII-like 3
    nei endonuclease VIII-like 3
    nei-like protein 3
    NP_001029662.1
    XP_015316314.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034490.2NP_001029662.1  endonuclease 8-like 3

      See identical proteins and their annotated locations for NP_001029662.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105168
      UniProtKB/Swiss-Prot
      F1N383, Q3MHN7
      Related
      ENSBTAP00000007661.5, ENSBTAT00000007661.5
      Conserved Domains (5) summary
      cd08969
      Location:1153
      MeNeil3_N; N-terminal domain of metazoan Nei-like glycosylase 3 (NEIL3)
      sd00029
      Location:323342
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:319347
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam06831
      Location:159229
      H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain
      pfam06839
      Location:553597
      zf-GRF; GRF zinc finger

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037354.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      8574871..8621182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015460828.3XP_015316314.2  endonuclease 8-like 3 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M0I9
      Related
      ENSBTAP00000083507.1, ENSBTAT00000094839.1
      Conserved Domains (5) summary
      cd08969
      Location:1153
      MeNeil3_N; N-terminal domain of metazoan Nei-like glycosylase 3 (NEIL3)
      sd00029
      Location:298317
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:294322
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam06839
      Location:528572
      zf-GRF; GRF zinc finger
      cl26942
      Location:60258
      H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain