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Items: 4

1.

Effect of OMP on gene expression in the olfactory epithelium

(Submitter supplied) OMP is expressed only in mature olfactory sensory neurons, arguing that its function is specially suited to the needs of OSNs. However none of the properties of OMP suggest any direct role in regulating gene expression in OSNs. Our data confirms that gene expression in the olfactory epithelium of mice lacking OMP is indistinguishable from mice expressing OMP. We used affymerix M430v2.0 gene chips to cover as much of genome as possible and observed no statistically significant differences in mRNA abundance between the two genotypes.These results imply that OMPs ability to regulate signal transduction with in OSNs has little effect on gene expression and that its ability to promote mitosis in neighbouring cells (under culture conditions) is insufficiently active under normal laboratory housing conditions to generate detectable differences in gene expression patterns. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2937
Platform:
GPL1261
6 Samples
Download data
Series
Accession:
GSE4927
ID:
200004927
2.
Full record GDS2937

Olfactory marker protein deficiency effect on the olfactory epithelium

Analysis of heterozygous and homozygous olfactory marker protein (OMP) null olfactory epithelial cells. OMP is expressed only in mature olfactory sensory neurons (OSNs). Results provide insight into the function of OMP.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE4927
6 Samples
Download data
DataSet
Accession:
GDS2937
ID:
2937
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4538 Series
40 Related Platforms
58877 Samples
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Platform
Accession:
GPL1261
ID:
100001261
4.

OMP-GFP heterozygous 3

Organism:
Mus musculus
Source name:
Olfactory epithelium
Platform:
GPL1261
Series:
GSE4927
Dataset:
GDS2937
Download data
Sample
Accession:
GSM111142
ID:
300111142
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