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Items: 4

1.

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Other; Expression profiling by high throughput sequencing
9 related Platforms
118 Samples
Download data: RCC, TXT
Series
Accession:
GSE52947
ID:
200052947
2.

Inflammation gene profile of sc-microglia in SOD mice

(Submitter supplied) Amyotrophic lateral sclerosis (ALS) is a paralytic degenerative disease of the nervous system. In the SOD1 mouse model of ALS we found loss of the molecular and functional microglia signature associated with pronounced expression of miR-155 in SOD1 mice. We also found increased expression of miR-155 in the spinal cord of ALS subjects. Genetic ablation of miR-155 increased survival in SOD1 mice and reversed the abnormal microglial and monocyte molecular signature. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL17981
14 Samples
Download data: RCC
Series
Accession:
GSE52673
ID:
200052673
3.

Nanostring mouse Inflammation kit

(Submitter supplied) according to the manufacturer’s protocol
Organism:
Mus musculus
2 Series
14 Samples
Download data
Platform
Accession:
GPL17981
ID:
100017981
4.

MG-SC (SOD1/miR155-/-)-1

Organism:
Mus musculus
Source name:
Mouse -B6/SJL-mSOD1G93A-miR-155-/-
Platform:
GPL17981
Series:
GSE52673 GSE52947
Download data: RCC
Sample
Accession:
GSM1273910
ID:
301273910
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