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Items: 4

1.

MG447 profile of lumbar spinal cord homogenate from healthy controls and ALS

(Submitter supplied) Amyotrophic lateral sclerosis (ALS) is a paralytic degenerative disease of the nervous system. In the SOD1 mouse model of ALS we found loss of the molecular and functional microglia signature associated with pronounced expression of miR-155 in SOD1 mice. We also found increased expression of miR-155 in the spinal cord of ALS subjects. Genetic ablation of miR-155 increased survival in SOD1 mice and reversed the abnormal microglial and monocyte molecular signature. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL18023
16 Samples
Download data: RCC
Series
Accession:
GSE52959
ID:
200052959
2.

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Other; Expression profiling by high throughput sequencing
9 related Platforms
118 Samples
Download data: RCC, TXT
Series
Accession:
GSE52947
ID:
200052947
3.

MG447 custom Nanostring codesets

(Submitter supplied) according to the manufacturer’s protocol
Organism:
Homo sapiens
2 Series
16 Samples
Download data
Platform
Accession:
GPL18023
ID:
100018023
4.

HC A13-14

Organism:
Homo sapiens
Source name:
Whole spinal cord homogenate - post mortem obtained from non ALS donor
Platform:
GPL18023
Series:
GSE52947 GSE52959
Download data: RCC
Sample
Accession:
GSM1278615
ID:
301278615
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Supplemental Content

db=gds|term=GSM1278615[Accession]|query=1|qty=3|blobid=MCID_665d44a1b6fda6219938ffa6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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