Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.
Full record GDS3929

Tobacco smoke effect on maternal and fetal cells

Analysis of peripheral blood leukocytes and placenta of pregnant smokers. Umbilical cord blood leukocytes of their newborns also examined. Maternal smoking has a negative effect on all stages of pregnancy. Results provide insight into molecular mechanisms underlying tobacco smoke-related defects.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 3 specimen sets
Platform:
GPL6883
Series:
GSE27272
183 Samples
Download data
DataSet
Accession:
GDS3929
ID:
3929
2.

Comprehensive Study of Tobacco Smoke-Related Transcriptome Alterations in Maternal and Fetal Cells

(Submitter supplied) Maternal smoking has a severe negative effect on all stages of pregnancy that in consequence impairs fetal growth and development. Tobacco smoke-related defects are well established at the clinical level; however, little is known about molecular mechanisms underlying these pathological conditions. We thus employed a genomic approach to determine transcriptome alterations induced by maternal smoking in pregnancy. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3929
Platform:
GPL6883
183 Samples
Download data: TXT
Series
Accession:
GSE27272
ID:
200027272
3.

Effect of maternal tobacco smoke exposure on the placental transcriptome

(Submitter supplied) Smoking in pregnancy increases a woman's risk of preterm delivery resulting in serious health problems during the newborn period, chronic lifelong disabilities (such as cerebral palsy, mental retardation and learning problems), and even death. Further, smoking women have placental problems such as placenta previa (a low-lying placenta that covers part or all of the opening of the uterus), placental abruption (in which the placenta peels away, partially or almost completely before delivery) often resulting in bleeding during delivery. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3793
Platform:
GPL6104
76 Samples
Download data: TXT
Series
Accession:
GSE18044
ID:
200018044
4.
Full record GDS3793

Tobacco smoke effect on the placenta

Analysis of placentas of women who smoked during pregnancy. Smoking increases the risk of preterm delivery and complications such as placental previa and abruption. Results provide insight into the molecular basis of smoke-induced placental abnormalities.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 dose sets
Platform:
GPL6104
Series:
GSE18044
76 Samples
Download data
DataSet
Accession:
GDS3793
ID:
3793
5.

Deregulation of Gene Expression induced by Environmental Tobacco Smoke Exposure in Pregnancy

(Submitter supplied) Passive smoke intake by pregnant women may have detrimental effects such as spontaneous abortion, lower birth weight, stillbirth, and reduced infant lung function. To extend our knowledge on molecular effects of tobacco smoke exposure in pregnancy, we analyzed transcriptome alterations in passive smokers (PS) and compared them to those in active smokers (AS). Using Illumina Expression Beadchip with 24,526 transcript probes, gene expression patterns were assayed in placentas from PS (N=25) exposed to environmental tobacco smoke (ETS) throughout pregnancy and non-exposed (NS) counterparts (N=35), and in cord blood cells from their newborns. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6883
104 Samples
Download data: TXT
Series
Accession:
GSE30032
ID:
200030032
6.

Microarray Analysis of Differentially Expressed Genes in Placental Tissue of Severe Preeclampsia

(Submitter supplied) Pre-eclampsia is one of the most serious pregnancy-associated disorders, and is defined by hypertension (systolic blood pressure higher than 140mmHg or diastolic blood pressure higher than 90mmHg) with proteinuria (more than 0.3g/day). It is not a simple complication of pregnancy, but is rather a syndrome of multiple organ failure involving the liver, kidney, and lung, as well as coagulatory and neural systems. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2080
Platform:
GPL1708
14 Samples
Download data
Series
Accession:
GSE4707
ID:
200004707
7.
Full record GDS2080

Early and late onset severe preeclampsia: placenta

Analysis of placentas from patients with early or late onset severe preeclampsia. Preeclampsia is a serious pregnancy-associated disorder characterized by hypertension and proteinuria. Results provide insight into the pathogenesis of preeclampsia.
Organism:
Homo sapiens
Type:
Expression profiling by array, log10 ratio, 3 disease state sets
Platform:
GPL1708
Series:
GSE4707
14 Samples
Download data
DataSet
Accession:
GDS2080
ID:
2080
8.

Full-term placenta, smokers and non-smokers

(Submitter supplied) Gene expression in placenta from 5 smoking and 5 non-smoking mothers analyzed by Affymetrix Hg133_plus2 microarrays. Keywords: Toxic response
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2990
Platform:
GPL570
10 Samples
Download data: CEL
Series
Accession:
GSE7434
ID:
200007434
9.
Full record GDS2990

Cigarette smoking effect on full-term placenta

Analysis of full-term placentas exposed to maternal cigarette smoke. The placenta produces and metabolizes steroids and xenobiotics. Results provide insight into the effects of maternal cigarette smoking on the placenta at term, with a focus on xenobiotic- and steroid-metabolizing genes.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 gender, 2 stress sets
Platform:
GPL570
Series:
GSE7434
10 Samples
Download data: CEL
DataSet
Accession:
GDS2990
ID:
2990
10.

The obese fetal transcriptome

(Submitter supplied) The objective of this study was to identify the tissue expression patterns and biological pathways enriched in term cord blood fetal RNA of obese women compared to lean In fetuses of obese women, 683 differentially regulated genes were identified.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
16 Samples
Download data: CEL
Series
Accession:
GSE60403
ID:
200060403
11.

Neurocognitive impairment at 18-24 months in children born preterm may originate in utero: a microarray study

(Submitter supplied) To characterize the molecular profile of the chorioamniotic membranes of preterm neonates with and without neurocognitive impairment at 18-24 months and (2) to determine if neonates who developed neurocognitive impairment can be identified at birth.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
28 Samples
Download data: TXT
Series
Accession:
GSE61822
ID:
200061822
12.

Characterization of the Placental Transcriptome through Mid to Late Gestation in the Mare

(Submitter supplied) The placenta is a dynamic organ which undergoes extensive remodeling throughout pregnancy to support, protect and nourish the developing fetus. Despite the importance of the placenta, very little is known about its gene expression beyond very early pregnancy and post-partum. Therefore, we utilized RNA-sequencing to characterize the transcriptome from the fetal (chorioallantois) and maternal (endometrium) components of the placenta from mares throughout gestation (4, 6, 10, 11 m). more...
Organism:
Equus caballus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24409
15 Samples
Download data: XLSX
Series
Accession:
GSE136691
ID:
200136691
13.

Fetal transcripts in maternal blood

(Submitter supplied) The discovery of fetal mRNA transcripts in maternal circulation holds great promise for noninvasive prenatal diagnosis. To identify potential fetal biomarkers, we studied whole blood and plasma transcripts common to term pregnant women and their newborns but reduced or absent in the postpartum mothers. In whole blood, 157 potentially-fetal transcripts were identified. RT-PCR confirmed the presence of specific transcripts, SNP analysis confirmed the presence of fetal transcripts in maternal circulation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL96
46 Samples
Download data: CEL
Series
Accession:
GSE53669
ID:
200053669
14.

Effects of Prenatal Tobacco Exposure on Gene Expression Profiling in Umbilical Cord Tissue

(Submitter supplied) Maternal smoking doubles the risk of delivering a low birth weight infant. The purpose of this study was to analyze differential gene expression in umbilical cord tissue as a function of maternal smoking, with an emphasis on growth-related genes. We recruited 15 pregnant smokers and 15 women who never smoked during pregnancy to participate RNA was isolated from umbilical cord tissue collected and snap frozen at the time of delivery. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
30 Samples
Download data
Series
Accession:
GSE11798
ID:
200011798
15.

Whole Blood Cell Gene Expression Profiling in Patients with Coronary Artery Disease (Homo sapiens)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL4133
393 Samples
Download data: TXT
Series
Accession:
GSE20686
ID:
200020686
16.

Whole Blood Cell Gene Expression Profiling in Patients with Coronary Artery Disease from the PREDICT Trial

(Submitter supplied) Expression profiling of whole blood cells isolated from patients piror to undergoing cardiac catheterization. PREDICT is a prospective, multi-center coronary catheter-lab trial being run in the US for the purpose of identifying biomarkers associated with coronary disease. A summary of the trial can be found at http://clinicaltrials.gov (identifier # NCT00500617).
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL4133
198 Samples
Download data: TXT
Series
Accession:
GSE20681
ID:
200020681
17.

Whole Blood Cell Gene Expression Profiling in Patients with Coronary Artery Disease from the Cathgen Registry

(Submitter supplied) Expression profiling of whole blood cells isolated from patients piror to undergoing cardiac catheterization. The Cathgen Registry is a single-center coronary catheter-lab cohort being run at Duke University for the purpose of identifying biomarkers associated with coronary disease.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL4133
195 Samples
Download data: TXT
Series
Accession:
GSE20680
ID:
200020680
18.

Gene expression profiles of T-lymphocytes are sensitive to the influence of heavy smoking

(Submitter supplied) Cigarette smoke components have a proven negative influence on human health. Adverse metabolic effects have been observed in tissues and single cells. As T-lymphocytes get in contact with affected organs (e.g. lung) or cells (e.g.erythrocytes), as well as with smoke components and bioactive molecules, whose production is influenced by them, we compared the gene exression profiles in these cells of the adaptive immune system of three male heavy smokers and three male non-smokers We combined rapid immuno-precipitation and Affymetrix GeneChip® HG U133A2.0 microarray analysis to analyse the data set. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2563
Platform:
GPL571
6 Samples
Download data
Series
Accession:
GSE4806
ID:
200004806
19.
Full record GDS2563

Cigarette smoking effect on T lymphocytes

Analysis of T lymphocytes of 3 male heavy smokers. Results provide insight into sensitivity of T lymphocytes to cigarette smoking.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 specimen sets
Platform:
GPL571
Series:
GSE4806
5 Samples
Download data
DataSet
Accession:
GDS2563
ID:
2563
20.

Evidence for functional interactions between the placenta and brain in pregnant mice

(Submitter supplied) In this study, we profiled gene expression of maternal brain, fetal brain and placenta at day 15 of pregnancy to investigate global crosstalk of genes between placenta and brain in mice .
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
16 Samples
Download data: TXT
Series
Accession:
GSE121799
ID:
200121799
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=4|blobid=MCID_614fe1bcff66263778097c4e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center