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wrap53 WD repeat containing, antisense to TP53 [ Danio rerio (zebrafish) ]

Gene ID: 321796, updated on 27-Mar-2024

Summary

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Official Symbol
wrap53provided by ZNC
Official Full Name
WD repeat containing, antisense to TP53provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-515
See related
Ensembl:ENSDARG00000086150 AllianceGenome:ZFIN:ZDB-GENE-030131-515
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb34f12; fi26g08; wu:fb34f12; wu:fi26g08
Summary
Predicted to enable RNA binding activity. Predicted to be involved in Cajal body organization. Predicted to be active in Cajal body. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 3; colorectal cancer; head and neck squamous cell carcinoma; lung non-small cell carcinoma; and ovarian cancer. Orthologous to human WRAP53 (WD repeat containing antisense to TP53). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See wrap53 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (20917595..20940213)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (20651599..20673875)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene fission, mitochondrial 1 Neighboring gene GRB10 interacting GYF protein 1a Neighboring gene si:dkey-111f13.5 Neighboring gene ephrin-B3b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Cajal body organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Cajal body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
telomerase Cajal body protein 1
Names
WD repeat domain 79

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256028.1 → NP_001242957.1  telomerase Cajal body protein 1

    See identical proteins and their annotated locations for NP_001242957.1

    Status: VALIDATED

    Source sequence(s)
    CR388099
    UniProtKB/TrEMBL
    A0A8M1P3C1, E7F3D5
    Related
    ENSDARP00000105980.1, ENSDART00000129161.4
    Conserved Domains (3) summary
    COG2319
    Location:160 → 478
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:166 → 210
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:160 → 474
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    20917595..20940213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005172209.4 → XP_005172266.1  telomerase Cajal body protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005172266.1

    UniProtKB/TrEMBL
    A0A8M1P3C1, E7F3D5
    Conserved Domains (3) summary
    COG2319
    Location:160 → 478
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:166 → 210
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:160 → 474
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

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