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wdr21 WD repeat domain 21 [ Danio rerio (zebrafish) ]

Gene ID: 393674, updated on 27-Mar-2024

Summary

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Official Symbol
wdr21provided by ZNC
Official Full Name
WD repeat domain 21provided by ZNC
Primary source
ZFIN:ZDB-GENE-040109-2
See related
Ensembl:ENSDARG00000110654 AllianceGenome:ZFIN:ZDB-GENE-040109-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:73069
Summary
Orthologous to human DCAF4 (DDB1 and CUL4 associated factor 4); DCAF4L1 (DDB1 and CUL4 associated factor 4 like 1); and DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See wdr21 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (28422544..28434024, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (3284952..3288548)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (28523819..28531099, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class H Neighboring gene zinc finger, FYVE domain containing 1 Neighboring gene double PHD fingers 3 Neighboring gene regulator of G protein signaling 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC73069

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DDB1- and CUL4-associated factor 4; WD repeat domain 21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200701.1 → NP_956995.1  WD repeat domain 21

    See identical proteins and their annotated locations for NP_956995.1

    Status: PROVISIONAL

    Source sequence(s)
    AY423032
    UniProtKB/TrEMBL
    Q6PC79
    Related
    ENSDARP00000155012.1, ENSDART00000182824.1
    Conserved Domains (3) summary
    COG2319
    Location:119 → 474
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:278 → 315
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:367 → 467
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    28422544..28434024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468379.1 → XP_021324054.1  DDB1- and CUL4-associated factor 4 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IMY2, A0A8M9PH68
    Related
    ENSDARP00000149987.1, ENSDART00000193381.1
    Conserved Domains (2) summary
    COG2319
    Location:119 → 472
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:278 → 315
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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