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PLA2G15 phospholipase A2 group XV [ Canis lupus familiaris (dog) ]

Gene ID: 403403, updated on 5-Mar-2024

Summary

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Official Symbol
PLA2G15provided by VGNC
Official Full Name
phospholipase A2 group XVprovided by VGNC
Primary source
VGNC:VGNC:44621
See related
Ensembl:ENSCAFG00845011578
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ACS; LLPL; LPLA2; LYPLA3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (81704925..81715711, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (81260068..81270848, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (81855603..81866386, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (81531643..81542423, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (81214083..81224865, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene protein arginine methyltransferase 7 Neighboring gene solute carrier family 7 member 6 opposite strand Neighboring gene solute carrier family 7 member 6 Neighboring gene epithelial splicing regulatory protein 2 Neighboring gene nuclear factor of activated T cells 3 Neighboring gene prefoldin subunit 6 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The acylation of lipophilic alcohols by lysosomal phospholipase A2. Abe A, et al. J Lipid Res, 2007 Oct. PMID 17626977
  2. Cloning and characterization of a lysosomal phospholipase A2, 1-O-acylceramide synthase. Hiraoka M, et al. J Biol Chem, 2002 Mar 22. PMID 11790796

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-independent phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylcholine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phospholipase A2 group XV
Names
1-O-acylceramide synthase
LCAT-like lysophospholipase
lysophospholipase 3 (lysosomal phospholipase A2)
lysosomal phospholipase A and acyltransferase
lysosomal phospholipase A2
NP_001002940.1
XP_038519973.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002940.1 → NP_001002940.1  phospholipase A2 group XV precursor

    See identical proteins and their annotated locations for NP_001002940.1

    Status: PROVISIONAL

    Source sequence(s)
    AY217754
    UniProtKB/Swiss-Prot
    Q6XPZ3
    UniProtKB/TrEMBL
    A0A8C0L0S3, A0A8C0SCG1, A0A8I3NE16
    Related
    ENSCAFP00845016103.1, ENSCAFT00845020534.1
    Conserved Domains (1) summary
    cl21494
    Location:80 → 392
    Abhydrolase; alpha/beta hydrolases

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    81704925..81715711 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664045.1 → XP_038519973.1  phospholipase A2 group XV isoform X1

    UniProtKB/TrEMBL
    A0A8C0SCG1, A0A8C0YWB2, A0A8I3NE16, A0A8P0T100
    Conserved Domains (1) summary
    cl21494
    Location:93 → 405
    Abhydrolase; alpha/beta hydrolases

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    81531643..81542423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    81214083..81224865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    81855603..81866386 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    81260068..81270848 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6XPZ3.1 GenPept UniProtKB/Swiss-Prot:Q6XPZ3

Gene LinkOut

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