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ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [ Canis lupus familiaris (dog) ]

Gene ID: 479481, updated on 5-Mar-2024

Summary

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Official Symbol
ACAP1provided by VGNC
Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1provided by VGNC
Primary source
VGNC:VGNC:37496
See related
Ensembl:ENSCAFG00845021641
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ACAP1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (32397200..32410802)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (32429841..32443451)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (32498439..32512044)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (32362625..32376257)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (32321395..32335005)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene neuralized E3 ubiquitin protein ligase 4 Neighboring gene uncharacterized LOC106558815 Neighboring gene potassium channel tetramerization domain containing 11 Neighboring gene transmembrane protein 95

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    32397200..32410802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038665378.1 → XP_038521306.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

    Conserved Domains (5) summary
    COG0666
    Location:560 → 698
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cl28907
    Location:405 → 524
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_038665379.1 → XP_038521307.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    COG0666
    Location:560 → 694
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:576 → 603
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038665380.1 → XP_038521308.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QHN8, A0A8I3PDU1
    Related
    ENSCAFP00845029929.1, ENSCAFT00845038211.1
    Conserved Domains (5) summary
    COG0666
    Location:560 → 693
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    32362625..32376257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475489.1 → XP_038331417.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

    Conserved Domains (5) summary
    COG0666
    Location:560 → 698
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cl28907
    Location:405 → 524
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_038475490.1 → XP_038331418.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    COG0666
    Location:560 → 694
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:576 → 603
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038475491.1 → XP_038331419.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

    Conserved Domains (5) summary
    COG0666
    Location:560 → 693
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    32321395..32335005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600837.1 → XP_038456765.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

  2. XM_038600838.1 → XP_038456766.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    COG0666
    Location:560 → 694
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:576 → 603
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038600839.1 → XP_038456767.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

    Conserved Domains (5) summary
    COG0666
    Location:560 → 693
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    32498439..32512044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038536655.1 → XP_038392583.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

    Conserved Domains (5) summary
    COG0666
    Location:560 → 698
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cl28907
    Location:405 → 524
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_038536656.1 → XP_038392584.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    COG0666
    Location:560 → 694
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:576 → 603
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038536657.1 → XP_038392585.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QHN8, A0A8I3PDU1
    Conserved Domains (5) summary
    COG0666
    Location:560 → 693
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    32429841..32443451
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038514910.1 → XP_038370838.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

    Conserved Domains (5) summary
    COG0666
    Location:560 → 698
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cl28907
    Location:405 → 524
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_038514919.1 → XP_038370847.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    COG0666
    Location:560 → 694
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:576 → 603
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_038514927.1 → XP_038370855.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0QHN8, A0A8I3PDU1
    Conserved Domains (5) summary
    COG0666
    Location:560 → 693
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13250
    Location:268 → 364
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:575 → 602
    ANK; ANK repeat [structural motif]
    cd08852
    Location:405 → 524
    ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
    cl12013
    Location:18 → 217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein
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