U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ugt2a6 UDP glucuronosyltransferase 2 family, polypeptide A6 [ Danio rerio (zebrafish) ]

Gene ID: 797211, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ugt2a6provided by ZNC
Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide A6provided by ZNC
Primary source
ZFIN:ZDB-GENE-081104-3
See related
Ensembl:ENSDARG00000039501 AllianceGenome:ZFIN:ZDB-GENE-081104-3
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-204e18.4
Summary
Predicted to enable glucuronosyltransferase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to several human genes including UGT2A2 (UDP glucuronosyltransferase family 2 member A2); UGT2B11 (UDP glucuronosyltransferase family 2 member B11); and UGT2B15 (UDP glucuronosyltransferase family 2 member B15). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (69856155..69867037)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (69083603..69093067)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene Rab interacting lysosomal protein-like 2 Neighboring gene fibronectin type III and SPRY domain containing 1-like Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide A5 Neighboring gene YTH N6-methyladenosine RNA binding protein C1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular evidence for multiple UDP-glucuronosyltransferase gene familes in fish. George SG, et al. Mar Environ Res, 2002 Sep-Dec. PMID 12408571
  2. Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases. Wang Y, et al. Mol Pharmacol, 2014 Jul. PMID 24728488
  3. Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity. Huang H, et al. PLoS One, 2010 Feb 10. PMID 20161780, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
UDP glucuronosyltransferase 2 family, polypeptide A6
NP_001138283.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144811.2 → NP_001138283.1  UDP glucuronosyltransferase 2 family, polypeptide A6 precursor

    Status: VALIDATED

    Source sequence(s)
    CU571335
    UniProtKB/TrEMBL
    A0A8M1NT44, B8JMA1
    Related
    ENSDARP00000068153.5, ENSDART00000073663.6
    Conserved Domains (2) summary
    PHA03392
    Location:254 → 485
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:21 → 519
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    69856155..69867037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002458787.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools