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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001276764.1 → NP_001263693.1  dystonin isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AC123072, AC124386, AC127433
- Consensus CDS
-
CCDS69874.1
- UniProtKB/TrEMBL
-
S4R1P5
- Related
- ENSMUSP00000138308.2, ENSMUST00000183034.5
- Conserved Domains (9) summary
-
- smart00150
Location:786 → 877
- SPEC; Spectrin repeats
- cd00014
Location:214 → 316
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:7310 → 7372
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6488 → 6703
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3715 → 4529
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00681
Location:1950 → 1990
- Plectin; Plectin repeat
- pfam02187
Location:7388 → 7461
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam13499
Location:7311 → 7371
- EF-hand_7; EF-hand domain pair
- cl02488
Location:1371 → 1535
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_010081.3 → NP_034211.2  dystonin isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (4, also known as e) has multiple differences in the coding region and UTRs compared to variant 1. This variant encodes isoform 4 (also known as e), which has distinct N- and C-termini and is significantly shorter than isoform 1.
- Source sequence(s)
-
AC127433
- Consensus CDS
-
CCDS69875.1
- UniProtKB/Swiss-Prot
-
Q91ZU6
- Related
- ENSMUSP00000138376.4, ENSMUST00000183302.6
- Conserved Domains (7) summary
-
- smart00150
Location:282 → 373
- SPEC; Spectrin repeats
- smart00250
Location:2504 → 2541
- PLEC; Plectin repeat
- COG1196
Location:721 → 1477
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00176
Location:375 → 563
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00681
Location:2467 → 2506
- Plectin; Plectin repeat
- pfam09728
Location:1399 → 1712
- Taxilin; Myosin-like coiled-coil protein
- cl02488
Location:867 → 1031
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_133833.4 → NP_598594.2  dystonin isoform 3
Status: VALIDATED
- Description
- Transcript Variant: This variant (3, also known as a) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also lacks seven alternate in-frame exons in the coding region. The encoded isoform (3, also known as a) has a distinct N-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AC123072, AC124386, AC127433
- Consensus CDS
-
CCDS35535.1
- UniProtKB/TrEMBL
-
A0A087WSP0
- Related
- ENSMUSP00000095393.3, ENSMUST00000097786.10
- Conserved Domains (8) summary
-
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- cd00014
Location:36 → 138
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:5009 → 5071
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4187 → 4402
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1480 → 2337
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam02187
Location:5087 → 5160
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam13499
Location:5010 → 5070
- EF-hand_7; EF-hand domain pair
- cl02488
Location:1193 → 1357
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_134448.4 → NP_604443.2  dystonin isoform 2
See identical proteins and their annotated locations for NP_604443.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2, also known as b) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also lacks two alternate in-frame exons in the coding region. The encoded isoform (2, also known as b) has a distinct N-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AC123072, AC124386, AC127433
- Consensus CDS
-
CCDS35534.1
- UniProtKB/Swiss-Prot
- E9PXE5, E9QL23, Q1KP04, Q3I6J6, Q60824, Q60845, Q8K5D4, Q91ZU6, Q91ZU7, Q91ZU8, Q9WU50, S4R1U5
- Related
- ENSMUSP00000095392.3, ENSMUST00000097785.10
- Conserved Domains (9) summary
-
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- cd00014
Location:36 → 138
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:7023 → 7085
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6201 → 6416
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3537 → 4351
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00681
Location:1772 → 1812
- Plectin; Plectin repeat
- pfam02187
Location:7101 → 7174
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam13499
Location:7024 → 7084
- EF-hand_7; EF-hand domain pair
- cl02488
Location:1193 → 1357
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000067.7Â Reference GRCm39 C57BL/6J
- Range
-
33946969..34347743
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006495666.4 → XP_006495729.1  dystonin isoform X3
- Conserved Domains (12) summary
-
- pfam05483
Location:1261 → 1451
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:786 → 877
- SPEC; Spectrin repeats
- COG1196
Location:4346 → 5241
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 432
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7311 → 7373
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6489 → 6704
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3662 → 4440
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1285 → 1723
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1951 → 1991
- Plectin; Plectin repeat
- pfam02187
Location:7388 → 7462
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1054 → 1120
- SH3_10; SH3 domain
- pfam18373
Location:1155 → 1232
- Spectrin_like; Spectrin like domain
-
XM_006495690.4 → XP_006495753.1  dystonin isoform X34
- Conserved Domains (12) summary
-
- pfam05483
Location:1261 → 1451
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00243
Location:7386 → 7458
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:786 → 877
- SPEC; Spectrin repeats
- COG1196
Location:4346 → 5241
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 432
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7311 → 7373
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6489 → 6704
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3662 → 4440
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1285 → 1723
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1951 → 1991
- Plectin; Plectin repeat
- pfam17902
Location:1054 → 1120
- SH3_10; SH3 domain
- pfam18373
Location:1155 → 1232
- Spectrin_like; Spectrin like domain
-
XM_006495691.4 → XP_006495754.1  dystonin isoform X33
- Conserved Domains (12) summary
-
- pfam05483
Location:1261 → 1451
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00243
Location:7277 → 7355
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:786 → 877
- SPEC; Spectrin repeats
- COG1196
Location:4346 → 5241
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 432
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7202 → 7264
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6380 → 6595
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3662 → 4440
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1285 → 1723
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1951 → 1991
- Plectin; Plectin repeat
- pfam17902
Location:1054 → 1120
- SH3_10; SH3 domain
- pfam18373
Location:1155 → 1232
- Spectrin_like; Spectrin like domain
-
XM_036158508.1 → XP_036014401.1  dystonin isoform X23
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- smart00150
Location:786 → 877
- SPEC; Spectrin repeats
- COG1196
Location:2332 → 3227
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00051
Location:5297 → 5359
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4475 → 4690
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1659 → 2516
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1385 → 1811
- CCDC158; Coiled-coil domain-containing protein 158
- pfam02187
Location:5374 → 5448
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1054 → 1120
- SH3_10; SH3 domain
- pfam18373
Location:1155 → 1232
- Spectrin_like; Spectrin like domain
- cd21236
Location:201 → 325
- CH_DYST_rpt1; first calponin homology (CH) domain found in dystonin and similar proteins
- cd21239
Location:330 → 433
- CH_DYST_rpt2; second calponin homology (CH) domain found in dystonin and similar proteins
-
XM_006495682.3 → XP_006495745.1  dystonin isoform X24
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- pfam05483
Location:1261 → 1451
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:786 → 877
- SPEC; Spectrin repeats
- COG1196
Location:2332 → 3227
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 432
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:5297 → 5359
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4475 → 4690
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1659 → 2516
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cl02488
Location:1372 → 1536
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam02187
Location:5374 → 5448
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1054 → 1120
- SH3_10; SH3 domain
- pfam18373
Location:1155 → 1232
- Spectrin_like; Spectrin like domain
-
XM_017314621.2 → XP_017170110.1  dystonin isoform X1
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam02187
Location:7400 → 7474
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314676.2 → XP_017170165.1  dystonin isoform X6
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam02187
Location:7400 → 7474
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314651.2 → XP_017170140.1  dystonin isoform X4
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00243
Location:7398 → 7476
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314687.2 → XP_017170176.1  dystonin isoform X8
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00243
Location:7398 → 7476
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314635.2 → XP_017170124.1  dystonin isoform X2
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam02187
Location:7400 → 7468
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_030246500.1 → XP_030102360.1  dystonin isoform X7
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam02187
Location:7400 → 7468
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314665.2 → XP_017170154.1  dystonin isoform X5
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00243
Location:7398 → 7470
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314706.2 → XP_017170195.1  dystonin isoform X11
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7214 → 7276
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6392 → 6607
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam02187
Location:7291 → 7365
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314722.2 → XP_017170211.1  dystonin isoform X14
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7214 → 7276
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6392 → 6607
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam02187
Location:7291 → 7365
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314794.2 → XP_017170283.1  dystonin isoform X22
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:2344 → 3239
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:5309 → 5371
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4487 → 4702
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1671 → 2528
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cl02488
Location:1384 → 1548
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam02187
Location:5386 → 5460
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314811.2 → XP_017170300.1  dystonin isoform X25
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:2344 → 3239
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:5200 → 5262
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4378 → 4593
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1671 → 2528
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cl02488
Location:1384 → 1548
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam02187
Location:5277 → 5351
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314689.2 → XP_017170178.1  dystonin isoform X9
- Conserved Domains (12) summary
-
- pfam05483
Location:1273 → 1463
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00243
Location:7398 → 7470
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:798 → 889
- SPEC; Spectrin repeats
- COG1196
Location:4358 → 5253
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:208 → 444
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7323 → 7385
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6501 → 6716
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3674 → 4452
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1297 → 1735
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1963 → 2003
- Plectin; Plectin repeat
- pfam17902
Location:1066 → 1132
- SH3_10; SH3 domain
- pfam18373
Location:1167 → 1244
- Spectrin_like; Spectrin like domain
-
XM_017314716.3 → XP_017170205.1  dystonin isoform X13
- Conserved Domains (12) summary
-
- pfam05483
Location:1135 → 1325
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:660 → 751
- SPEC; Spectrin repeats
- COG1196
Location:4220 → 5115
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:70 → 306
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7185 → 7247
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6363 → 6578
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3536 → 4314
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1159 → 1597
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1825 → 1865
- Plectin; Plectin repeat
- pfam02187
Location:7262 → 7336
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:928 → 994
- SH3_10; SH3 domain
- pfam18373
Location:1029 → 1106
- Spectrin_like; Spectrin like domain
-
XM_006495674.5 → XP_006495737.1  dystonin isoform X15
- Conserved Domains (12) summary
-
- pfam05483
Location:1123 → 1313
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:648 → 739
- SPEC; Spectrin repeats
- COG1196
Location:4208 → 5103
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:70 → 294
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7173 → 7235
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6351 → 6566
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3524 → 4302
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1147 → 1585
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1813 → 1853
- Plectin; Plectin repeat
- pfam02187
Location:7250 → 7324
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:916 → 982
- SH3_10; SH3 domain
- pfam18373
Location:1017 → 1094
- Spectrin_like; Spectrin like domain
-
XM_017314712.3 → XP_017170201.1  dystonin isoform X12
- Conserved Domains (12) summary
-
- pfam05483
Location:1139 → 1329
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:664 → 755
- SPEC; Spectrin repeats
- COG1196
Location:4224 → 5119
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:74 → 310
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7189 → 7251
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6367 → 6582
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3540 → 4318
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1163 → 1601
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1829 → 1869
- Plectin; Plectin repeat
- pfam02187
Location:7266 → 7340
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:932 → 998
- SH3_10; SH3 domain
- pfam18373
Location:1033 → 1110
- Spectrin_like; Spectrin like domain
-
XM_017314741.2 → XP_017170230.1  dystonin isoform X16
- Conserved Domains (12) summary
-
- pfam05483
Location:1095 → 1285
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:620 → 711
- SPEC; Spectrin repeats
- COG1196
Location:4180 → 5075
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:35 → 266
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7145 → 7207
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6323 → 6538
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3496 → 4274
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1119 → 1557
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1785 → 1825
- Plectin; Plectin repeat
- pfam02187
Location:7222 → 7296
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:888 → 954
- SH3_10; SH3 domain
- pfam18373
Location:989 → 1066
- Spectrin_like; Spectrin like domain
-
XM_006495678.4 → XP_006495741.1  dystonin isoform X18
- Conserved Domains (12) summary
-
- pfam05483
Location:1083 → 1273
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- COG1196
Location:4168 → 5063
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:35 → 254
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7133 → 7195
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6311 → 6526
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3484 → 4262
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1107 → 1545
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1773 → 1813
- Plectin; Plectin repeat
- pfam02187
Location:7210 → 7284
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:876 → 942
- SH3_10; SH3 domain
- pfam18373
Location:977 → 1054
- Spectrin_like; Spectrin like domain
-
XM_006495688.4 → XP_006495751.1  dystonin isoform X32
- Conserved Domains (12) summary
-
- pfam05483
Location:1083 → 1273
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- COG1196
Location:4168 → 5063
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:35 → 254
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7133 → 7195
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6311 → 6526
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3484 → 4262
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1107 → 1545
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1773 → 1813
- Plectin; Plectin repeat
- pfam02187
Location:7210 → 7284
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:876 → 942
- SH3_10; SH3 domain
- pfam18373
Location:977 → 1054
- Spectrin_like; Spectrin like domain
-
XM_017314848.2 → XP_017170337.1  dystonin isoform X31
- Conserved Domains (12) summary
-
- pfam05483
Location:1083 → 1273
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- COG1196
Location:4168 → 5063
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:35 → 254
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7024 → 7086
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6202 → 6417
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3484 → 4262
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1107 → 1545
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1773 → 1813
- Plectin; Plectin repeat
- pfam02187
Location:7101 → 7175
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:876 → 942
- SH3_10; SH3 domain
- pfam18373
Location:977 → 1054
- Spectrin_like; Spectrin like domain
-
XM_006495684.4 → XP_006495747.1  dystonin isoform X26
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- pfam05483
Location:1083 → 1273
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- COG1196
Location:2154 → 3049
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:35 → 254
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:5119 → 5181
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4297 → 4512
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1481 → 2338
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cl02488
Location:1194 → 1358
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam02187
Location:5196 → 5270
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:876 → 942
- SH3_10; SH3 domain
- pfam18373
Location:977 → 1054
- Spectrin_like; Spectrin like domain
-
XM_036158554.1 → XP_036014447.1  dystonin isoform X27
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- smart00243
Location:5194 → 5266
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- COG1196
Location:2154 → 3049
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00051
Location:5119 → 5181
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4297 → 4512
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1481 → 2338
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1207 → 1633
- CCDC158; Coiled-coil domain-containing protein 158
- pfam17902
Location:876 → 942
- SH3_10; SH3 domain
- pfam18373
Location:977 → 1054
- Spectrin_like; Spectrin like domain
- cd21236
Location:20 → 147
- CH_DYST_rpt1; first calponin homology (CH) domain found in dystonin and similar proteins
- cd21239
Location:152 → 255
- CH_DYST_rpt2; second calponin homology (CH) domain found in dystonin and similar proteins
-
XM_017314868.2 → XP_017170357.1  dystonin isoform X28
- UniProtKB/TrEMBL
-
A0A087WSP0
- Conserved Domains (11) summary
-
- pfam05483
Location:1083 → 1273
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:608 → 699
- SPEC; Spectrin repeats
- COG1196
Location:2154 → 3049
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:35 → 254
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:5010 → 5072
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4188 → 4403
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1481 → 2338
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cl02488
Location:1194 → 1358
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam02187
Location:5087 → 5161
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:876 → 942
- SH3_10; SH3 domain
- pfam18373
Location:977 → 1054
- Spectrin_like; Spectrin like domain
-
XM_017314750.3 → XP_017170239.1  dystonin isoform X17
- Conserved Domains (12) summary
-
- pfam05483
Location:1088 → 1278
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:613 → 704
- SPEC; Spectrin repeats
- COG1196
Location:4173 → 5068
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:28 → 259
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7138 → 7200
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6316 → 6531
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3489 → 4267
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1112 → 1550
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1778 → 1818
- Plectin; Plectin repeat
- pfam02187
Location:7215 → 7289
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:881 → 947
- SH3_10; SH3 domain
- pfam18373
Location:982 → 1059
- Spectrin_like; Spectrin like domain
-
XM_006495679.4 → XP_006495742.1  dystonin isoform X19
- Conserved Domains (12) summary
-
- pfam05483
Location:996 → 1186
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:521 → 612
- SPEC; Spectrin repeats
- COG1196
Location:4081 → 4976
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- COG5069
Location:1 → 167
- SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
- cd00051
Location:7046 → 7108
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6224 → 6439
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3397 → 4175
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1020 → 1458
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1686 → 1726
- Plectin; Plectin repeat
- pfam02187
Location:7123 → 7197
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:789 → 855
- SH3_10; SH3 domain
- pfam18373
Location:890 → 967
- Spectrin_like; Spectrin like domain
-
XM_006495669.5 → XP_006495732.1  dystonin isoform X10
- Conserved Domains (12) summary
-
- pfam05483
Location:1199 → 1389
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:724 → 815
- SPEC; Spectrin repeats
- COG1196
Location:4284 → 5179
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00014
Location:268 → 371
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00051
Location:7249 → 7311
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:6427 → 6642
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3600 → 4378
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:1223 → 1661
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1889 → 1929
- Plectin; Plectin repeat
- pfam02187
Location:7326 → 7400
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:992 → 1058
- SH3_10; SH3 domain
- pfam18373
Location:1093 → 1170
- Spectrin_like; Spectrin like domain
-
XM_006495686.5 → XP_006495749.1  dystonin isoform X30
- Conserved Domains (8) summary
-
- smart00150
Location:282 → 373
- SPEC; Spectrin repeats
- smart00250
Location:2505 → 2542
- PLEC; Plectin repeat
- COG1196
Location:678 → 1404
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00176
Location:375 → 564
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1098 → 1859
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00681
Location:2468 → 2507
- Plectin; Plectin repeat
- pfam17902
Location:550 → 616
- SH3_10; SH3 domain
- pfam18373
Location:651 → 728
- Spectrin_like; Spectrin like domain
-
XM_006495680.5 → XP_006495743.1  dystonin isoform X20
- Conserved Domains (11) summary
-
- pfam05483
Location:757 → 947
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:282 → 373
- SPEC; Spectrin repeats
- COG1196
Location:3842 → 4737
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00051
Location:6807 → 6869
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:5985 → 6200
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:3158 → 3936
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam15921
Location:781 → 1219
- CCDC158; Coiled-coil domain-containing protein 158
- pfam00681
Location:1447 → 1487
- Plectin; Plectin repeat
- pfam02187
Location:6884 → 6958
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:550 → 616
- SH3_10; SH3 domain
- pfam18373
Location:651 → 728
- Spectrin_like; Spectrin like domain
-
XM_006495685.2 → XP_006495748.1  dystonin isoform X29
- UniProtKB/TrEMBL
-
A0A087WSP0
- Related
- ENSMUSP00000141127.2, ENSMUST00000185269.7
- Conserved Domains (10) summary
-
- pfam05483
Location:757 → 947
- SCP-1; Synaptonemal complex protein 1 (SCP-1)
- smart00150
Location:282 → 373
- SPEC; Spectrin repeats
- COG1196
Location:1828 → 2723
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00051
Location:4793 → 4855
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:3971 → 4186
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1155 → 2012
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- cl02488
Location:868 → 1032
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam02187
Location:4870 → 4944
- GAS2; Growth-Arrest-Specific Protein 2 Domain
- pfam17902
Location:550 → 616
- SH3_10; SH3 domain
- pfam18373
Location:651 → 728
- Spectrin_like; Spectrin like domain
-
XM_030246701.2 → XP_030102561.1  dystonin isoform X21
- Conserved Domains (7) summary
-
- smart00150
Location:5322 → 5449
- SPEC; Spectrin repeats
- COG1196
Location:2518 → 3413
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00051
Location:5483 → 5545
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- cd00176
Location:4661 → 4876
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- TIGR02168
Location:1834 → 2612
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00681
Location:123 → 163
- Plectin; Plectin repeat
- pfam02187
Location:5560 → 5634
- GAS2; Growth-Arrest-Specific Protein 2 Domain