PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PPM1Hprovided by VGNC
Official Full Name: protein phosphatase, Mg2+/Mn2+ dependent 1Hprovided by VGNC
Primary source: VGNC:VGNC:44868
See related: Ensembl:ENSCAFG00845009918
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	10	NC_051814.1 (5855584..6109395, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	10	NC_006592.4 (5748686..6001877, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	10	NC_049231.1 (6185277..6439155, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	10	NC_049270.1 (5796507..6050145, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	10	NC_049751.1 (6047496..6300693, complement)

Chromosome 10 - NC_051814.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein phosphatase 1H

Names: protein phosphatase 1H (PP2C domain containing)

XP_022279841.1

EC 3.1.3.16

XP_022279842.1

EC 3.1.3.16

XP_038343912.1

EC 3.1.3.16

XP_038343913.1

EC 3.1.3.16

XP_038405805.1

EC 3.1.3.16

XP_038405806.1

EC 3.1.3.16

XP_038405807.1

EC 3.1.3.16

XP_038469777.1

EC 3.1.3.16

XP_038469778.1

EC 3.1.3.16

XP_038469779.1

EC 3.1.3.16

XP_038535130.1

EC 3.1.3.16

XP_038535131.1

EC 3.1.3.16

XP_038535132.1

EC 3.1.3.16

XP_531656.3

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051814.1 Reference ROS_Cfam_1.0

Range

5855584..6109395 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038679202.1 → XP_038535130.1 protein phosphatase 1H isoform X2

UniProtKB/TrEMBL

A0A8C0R485, A0A8C0RC54, A0A8I3NBZ8, A0A8I3NPJ9, A0A8P0TDZ3

Related

ENSCAFP00845013574.1, ENSCAFT00845017435.1

Conserved Domains (1) summary

cd00143
Location:142 → 506

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038679204.1 → XP_038535132.1 protein phosphatase 1H isoform X3

UniProtKB/TrEMBL

A0A8I3NPJ9, A0A8P0TDZ3

Conserved Domains (1) summary

cd00143
Location:142 → 462

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038679203.1 → XP_038535131.1 protein phosphatase 1H isoform X1

UniProtKB/TrEMBL

A0A8C0TBC2, A0A8P0TA72

Conserved Domains (1) summary

cd00143
Location:142 → 327

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049270.1 Alternate UMICH_Zoey_3.1

Range

5796507..6050145 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038487984.1 → XP_038343912.1 protein phosphatase 1H isoform X2

Conserved Domains (1) summary

cd00143
Location:142 → 506

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038487985.1 → XP_038343913.1 protein phosphatase 1H isoform X3

Conserved Domains (1) summary

cd00143
Location:142 → 462

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049751.1 Alternate UNSW_CanFamBas_1.0

Range

6047496..6300693 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038613849.1 → XP_038469777.1 protein phosphatase 1H isoform X2

Conserved Domains (1) summary

cd00143
Location:142 → 506

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038613851.1 → XP_038469779.1 protein phosphatase 1H isoform X3

Conserved Domains (1) summary

cd00143
Location:142 → 462

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038613850.1 → XP_038469778.1 protein phosphatase 1H isoform X4

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049231.1 Alternate UU_Cfam_GSD_1.0

Range

6185277..6439155 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038549877.1 → XP_038405805.1 protein phosphatase 1H isoform X2

UniProtKB/TrEMBL

A0A8C0R485, A0A8C0RC54, A0A8I3NBZ8, A0A8I3NPJ9, A0A8P0TDZ3

Conserved Domains (1) summary

cd00143
Location:142 → 506

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038549879.1 → XP_038405807.1 protein phosphatase 1H isoform X3

UniProtKB/TrEMBL

A0A8I3NPJ9, A0A8P0TDZ3

Conserved Domains (1) summary

cd00143
Location:142 → 462

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038549878.1 → XP_038405806.1 protein phosphatase 1H isoform X5

UniProtKB/TrEMBL

A0A8C0TBC2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

5748686..6001877 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_531656.7 → XP_531656.3 protein phosphatase 1H isoform X2

UniProtKB/TrEMBL

A0A8C0R485, A0A8C0RC54, A0A8I3NBZ8, A0A8I3NPJ9, A0A8P0TDZ3

Conserved Domains (1) summary

cd00143
Location:142 → 506

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_022424134.2 → XP_022279842.1 protein phosphatase 1H isoform X3

UniProtKB/TrEMBL

A0A8I3NPJ9, A0A8P0TDZ3

Conserved Domains (1) summary

cd00143
Location:142 → 462

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_022424133.2 → XP_022279841.1 protein phosphatase 1H isoform X1

UniProtKB/TrEMBL

A0A8C0TBC2, A0A8P0TA72

Conserved Domains (1) summary

cd00143
Location:142 → 327

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...