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    MIER1 MIER1 transcriptional regulator [ Homo sapiens (human) ]

    Gene ID: 57708, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MIER1provided by HGNC
    Official Full Name
    MIER1 transcriptional regulatorprovided by HGNC
    Primary source
    HGNC:HGNC:29657
    See related
    Ensembl:ENSG00000198160 MIM:616848; AllianceGenome:HGNC:29657
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ER1; MI-ER1
    Summary
    This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]
    Expression
    Ubiquitous expression in bone marrow (RPKM 19.6), colon (RPKM 10.3) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    1p31.3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (66924990..66988619)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (66802518..66866111)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (67390673..67454302)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene insulin like 5 Neighboring gene dynein axonemal intermediate chain 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1167 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 973 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1168 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 974 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 975 Neighboring gene MPRA-validated peak274 silencer Neighboring gene MPRA-validated peak275 silencer Neighboring gene solute carrier family 35 member D1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 976 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:67486227-67487025 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 977 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 978 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:67562817-67563435 Neighboring gene small nucleolar RNA SNORA31 Neighboring gene chromosome 1 open reading frame 141 Neighboring gene NANOG hESC enhancer GRCh37_chr1:67602886-67603396 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1169 Neighboring gene interleukin 23 receptor Neighboring gene RNA, U6 small nuclear 586, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells. Clements JA, et al. PLoS One, 2012. PMID 22384264, Free PMC Article
    2. Changes in subcellular localisation of MI-ER1 alpha, a novel oestrogen receptor-alpha interacting protein, is associated with breast cancer progression. McCarthy PL, et al. Br J Cancer, 2008 Aug 19. PMID 18665173, Free PMC Article
    3. Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization. Paterno GD, et al. Gene, 2002 Jul 24. PMID 12242014
    4. Molecular cloning of human er1 cDNA and its differential expression in breast tumours and tumour-derived cell lines. Paterno GD, et al. Gene, 1998 Nov 5. PMID 9813250
    5. Protein expression pattern of human MIER1 alpha, a novel estrogen receptor binding protein. McCarthy PL, et al. J Mol Histol, 2013 Aug. PMID 23277184, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A potential histone-chaperone activity for the MIER1 histone deacetylase complex.
      Title: A potential histone-chaperone activity for the MIER1 histone deacetylase complex.
    2. Histone deacetylase assays confirmed that MIER2, but not MIER3 complexes, have associated deacetylase activity.
      Title: Differential HDAC1 and 2 Recruitment by Members of the MIER Family.
    3. Biochemical analysis of the BAHD1-associated multiprotein complex identifies MIER proteins as novel partners of BAHD1 and suggests that BAHD1-MIER interaction forms a hub for histone deacetylases and methyltransferases
      Title: Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.
    4. Insulin and IGF-1 alter the subcellular localization of MIER1alpha in breast carcinoma cells.
      Title: Insulin and IGF-1, but not 17β-estradiol, alter the subcellular localization of MIER1α in MCF7 breast carcinoma cells.
    5. nuclear targeting of MIER1alpha requires an intact ELM2 domain and is dependent on interaction with HDAC1/2
      Title: Nuclear localization of the transcriptional regulator MIER1α requires interaction with HDAC1/2 in breast cancer cells.
    6. the first immunohistochemical study of the MIER1alpha protein expression pattern in human tissues, is reported.
      Title: Protein expression pattern of human MIER1 alpha, a novel estrogen receptor binding protein.
    7. Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells
      Title: Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells.
    8. Loss of nuclear MI-ER1 alpha might contribute to the development of invasive breast carcinoma
      Title: Changes in subcellular localisation of MI-ER1 alpha, a novel oestrogen receptor-alpha interacting protein, is associated with breast cancer progression.
    9. we investigated the role of hMI-ER1alpha and hMI-ER1beta in the regulation of transcription.We demonstrate that this repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
      Title: Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain.
    10. the association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters
      Title: The SANT domain of human MI-ER1 interacts with Sp1 to interfere with GC box recognition and repress transcription from its own promoter.
    Submit: New GeneRIF Correction See all GeneRIFs (11)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA1610, MGC131940, MGC150640, MGC150641, DKFZp781G0451

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to histone deacetylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histone deacetylase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone deacetylase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of canonical NF-kappaB signal transduction HMP PubMed 
    involved_in regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of transcription repressor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mesoderm induction early response protein 1
    Names
    mesoderm induction early response 1 homolog
    mesoderm induction early response 1, transcriptional regulator

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029847.1 RefSeqGene

      Range
      5096..68725
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001077700.3 → NP_001071168.2  mesoderm induction early response protein 1 isoform b

      See identical proteins and their annotated locations for NP_001071168.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region and uses an alternate upstream translation start site, compared to variant 1. The resulting isoform (b) has a longer and distinct N-terminus, compared to isoform a.
      Source sequence(s)
      AK302061, AL500525, BM987758
      Consensus CDS
      CCDS53326.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000383820.1, ENST00000401041.6
      Conserved Domains (2) summary
      cd11661
      Location:341 → 385
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:235 → 284
      ELM2; ELM2 domain

    2. NM_001077701.3 → NP_001071169.1  mesoderm induction early response protein 1 isoform c

      See identical proteins and their annotated locations for NP_001071169.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The resulting isoform (c, also known as N3-beta) has a shorter and distinct N-terminus, compared to isoform a.
      Source sequence(s)
      AF515446, AL500525, BM987758
      Consensus CDS
      CCDS41348.1
      UniProtKB/Swiss-Prot
      C9JFD4, Q08AE0, Q32NC4, Q5T104, Q5TAD1, Q5TAD2, Q5TAD4, Q5TAD5, Q6AHY8, Q86TB4, Q8N108, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2
      Related
      ENSP00000347514.3, ENST00000355356.3
      Conserved Domains (2) summary
      cd11661
      Location:288 → 332
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:182 → 231
      ELM2; ELM2 domain

    3. NM_001077702.3 → NP_001071170.2  mesoderm induction early response protein 1 isoform d

      See identical proteins and their annotated locations for NP_001071170.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (d) has a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AF515448, AK302061, AL500525, BM987758
      Consensus CDS
      CCDS53327.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000360055.1, ENST00000371016.5
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    4. NM_001077703.3 → NP_001071171.2  mesoderm induction early response protein 1 isoform e

      See identical proteins and their annotated locations for NP_001071171.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an alternate exon in the 5' coding region, uses an alternate upstream translation start site, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (e) has a longer and distinct N-terminus and a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AK302061, AL500525, AY124187, BM987758
      Consensus CDS
      CCDS53325.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000360053.1, ENST00000371014.5
      Conserved Domains (2) summary
      cd11661
      Location:341 → 385
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:235 → 284
      ELM2; ELM2 domain

    5. NM_001077704.3 → NP_001071172.1  mesoderm induction early response protein 1 isoform f

      See identical proteins and their annotated locations for NP_001071172.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at an alternate start codon, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (f, also known as N3-alpha), has shorter and distinct N- and C-termini, compared to isoform a.
      Source sequence(s)
      AL500525, AY124188, BM987758
      Consensus CDS
      CCDS41347.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000383821.3, ENST00000401042.7
      Conserved Domains (2) summary
      cd11661
      Location:288 → 332
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:182 → 231
      ELM2; ELM2 domain

    6. NM_001146110.2 → NP_001139582.1  mesoderm induction early response protein 1 isoform a

      See identical proteins and their annotated locations for NP_001139582.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) uses an alternate splice site in the 5' UTR compared to variant 1. Both variants 1 and 10 encode the same isoform (a).
      Source sequence(s)
      AK302061, AK307717, AL500525, BC108726, BM987758
      Consensus CDS
      CCDS53329.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000350321.2, ENST00000357692.6
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    7. NM_001146111.2 → NP_001139583.1  mesoderm induction early response protein 1 isoform g

      See identical proteins and their annotated locations for NP_001139583.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (g) has a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AK302061, AL500525, BC108726, BM987758
      Consensus CDS
      CCDS53328.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000360057.3, ENST00000371018.7
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    8. NM_001146112.2 → NP_001139584.1  mesoderm induction early response protein 1 isoform h

      See identical proteins and their annotated locations for NP_001139584.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) lacks a portion of the 5' coding region and initiates translation at a downstream in-frame start codon, compared to variant 1. The resulting isoform (h) has a shorter N-terminus, compared to isoform a.
      Source sequence(s)
      AF515446, AK302061, AL139216, AL500525, BM987758
      UniProtKB/Swiss-Prot
      Q8N108
      Conserved Domains (2) summary
      cd11661
      Location:261 → 305
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:155 → 204
      ELM2; ELM2 domain

    9. NM_001146113.2 → NP_001139585.1  mesoderm induction early response protein 1 isoform i

      See identical proteins and their annotated locations for NP_001139585.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) lacks two alternate exons in the 5' coding region, initiates translation at a downsteram in-frame start codon, and lacks an alternate segment in the 3' coding region, compared to variant 1. The resulting isoform (i) has a shorter N-terminus and a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AK302061, AL500525, BC125217, BM987758
      Consensus CDS
      CCDS53330.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000348253.6, ENST00000355977.10
      Conserved Domains (2) summary
      cd11661
      Location:225 → 269
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:119 → 168
      ELM2; ELM2 domain

    10. NM_001278215.2 → NP_001265144.1  mesoderm induction early response protein 1 isoform j

      See identical proteins and their annotated locations for NP_001265144.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) lacks multiple 3' exons and its transcription extends past a splice site used in variant 1, resulting in a distinct 3' coding region and 3' UTR. The encoded isoform (j) has a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AL139216, BC066898
      Consensus CDS
      CCDS60163.1
      UniProtKB/Swiss-Prot
      Q8N108
      Related
      ENSP00000360051.2, ENST00000371012.6

    11. NM_001350530.2 → NP_001337459.1  mesoderm induction early response protein 1 isoform k

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) contains an alternate exon in its 5' coding region, resulting in a shorter 5' UTR and the use of an alternate upstream translation start site, compared to variant 1. The resulting isoform (k) has a longer and distinct N-terminus, compared to isoform a
      Source sequence(s)
      AF515448, AK302061, AL139216, AL500525, BM987758, CB998535
      Conserved Domains (2) summary
      cd11661
      Location:378 → 422
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:272 → 321
      ELM2; ELM2 domain

    12. NM_020948.4 → NP_065999.2  mesoderm induction early response protein 1 isoform a

      See identical proteins and their annotated locations for NP_065999.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform a. Both variants 1 and 10 encode the same isoform (a).
      Source sequence(s)
      AF515448, AK302061, AL500525, BM987758
      Consensus CDS
      CCDS53329.1
      UniProtKB/Swiss-Prot
      Q8N108
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      66924990..66988619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017001923.2 → XP_016857412.1  mesoderm induction early response protein 1 isoform X4

    2. XM_011541865.3 → XP_011540167.1  mesoderm induction early response protein 1 isoform X1

      Conserved Domains (3) summary
      smart00717
      Location:365 → 410
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:365 → 409
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:259 → 308
      ELM2; ELM2 domain

    3. XM_047426266.1 → XP_047282222.1  mesoderm induction early response protein 1 isoform X10

    4. XM_017001928.3 → XP_016857417.1  mesoderm induction early response protein 1 isoform X6

      UniProtKB/Swiss-Prot
      Q8N108
      Conserved Domains (2) summary
      cd11661
      Location:287 → 331
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:181 → 230
      ELM2; ELM2 domain

    5. XM_047426256.1 → XP_047282212.1  mesoderm induction early response protein 1 isoform X3

    6. XM_047426263.1 → XP_047282219.1  mesoderm induction early response protein 1 isoform X5

    7. XM_047426255.1 → XP_047282211.1  mesoderm induction early response protein 1 isoform X3

    8. XM_017001924.2 → XP_016857413.1  mesoderm induction early response protein 1 isoform X5

      UniProtKB/Swiss-Prot
      Q8N108
      Conserved Domains (2) summary
      cd11661
      Location:305 → 349
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:199 → 248
      ELM2; ELM2 domain

    9. XM_017001919.2 → XP_016857408.1  mesoderm induction early response protein 1 isoform X2

      Conserved Domains (3) summary
      smart00717
      Location:324 → 369
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:324 → 368
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:218 → 267
      ELM2; ELM2 domain

    10. XM_047426260.1 → XP_047282216.1  mesoderm induction early response protein 1 isoform X5

    11. XM_017001931.2 → XP_016857420.1  mesoderm induction early response protein 1 isoform X8

      UniProtKB/Swiss-Prot
      Q8N108
      Conserved Domains (2) summary
      cd11661
      Location:261 → 305
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:155 → 204
      ELM2; ELM2 domain

    12. XM_047426264.1 → XP_047282220.1  mesoderm induction early response protein 1 isoform X7

    13. XM_017001927.2 → XP_016857416.1  mesoderm induction early response protein 1 isoform X6

      UniProtKB/Swiss-Prot
      Q8N108
      Conserved Domains (2) summary
      cd11661
      Location:287 → 331
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:181 → 230
      ELM2; ELM2 domain

    14. XM_047426265.1 → XP_047282221.1  mesoderm induction early response protein 1 isoform X9

    15. XM_017001920.2 → XP_016857409.1  mesoderm induction early response protein 1 isoform X2

      Conserved Domains (3) summary
      smart00717
      Location:324 → 369
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:324 → 368
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:218 → 267
      ELM2; ELM2 domain

    16. XM_017001930.2 → XP_016857419.1  mesoderm induction early response protein 1 isoform X7

      Conserved Domains (2) summary
      cd11661
      Location:287 → 331
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:181 → 230
      ELM2; ELM2 domain

    17. XM_017001933.2 → XP_016857422.1  mesoderm induction early response protein 1 isoform X9

    18. XM_017001934.2 → XP_016857423.1  mesoderm induction early response protein 1 isoform X9

    RNA

    1. XR_007062438.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      66802518..66866111
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054337911.1 → XP_054193886.1  mesoderm induction early response protein 1 isoform X4

    2. XM_054337908.1 → XP_054193883.1  mesoderm induction early response protein 1 isoform X1

    3. XM_054337921.1 → XP_054193896.1  mesoderm induction early response protein 1 isoform X10

    4. XM_054337914.1 → XP_054193889.1  mesoderm induction early response protein 1 isoform X6

    5. XM_054337912.1 → XP_054193887.1  mesoderm induction early response protein 1 isoform X5

    6. XM_054337913.1 → XP_054193888.1  mesoderm induction early response protein 1 isoform X5

    7. XM_054337910.1 → XP_054193885.1  mesoderm induction early response protein 1 isoform X3

    8. XM_054337909.1 → XP_054193884.1  mesoderm induction early response protein 1 isoform X2

    9. XM_054337917.1 → XP_054193892.1  mesoderm induction early response protein 1 isoform X8

    10. XM_054337920.1 → XP_054193895.1  mesoderm induction early response protein 1 isoform X2

    11. XM_054337916.1 → XP_054193891.1  mesoderm induction early response protein 1 isoform X6

    12. XM_054337915.1 → XP_054193890.1  mesoderm induction early response protein 1 isoform X7

    13. XM_054337918.1 → XP_054193893.1  mesoderm induction early response protein 1 isoform X9

    14. XM_054337919.1 → XP_054193894.1  mesoderm induction early response protein 1 isoform X9

    RNA

    1. XR_008486129.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N108.2 GenPept UniProtKB/Swiss-Prot:Q8N108

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