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    ERBIN erbb2 interacting protein [ Bos taurus (cattle) ]

    Gene ID: 512866, updated on 6-Jun-2024

    Summary

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    Official Symbol
    ERBINprovided by VGNC
    Official Full Name
    erbb2 interacting proteinprovided by VGNC
    Primary source
    VGNC:VGNC:28565
    See related
    Ensembl:ENSBTAG00000000415
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ERBIN in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (13529621..13659593, complement)

    Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene microtubule associated serine/threonine kinase family member 4 Neighboring gene uncharacterized LOC112442988 Neighboring gene microRNA mir-2285z Neighboring gene microRNA mir-2285q Neighboring gene splicing regulatory glutamic acid and lysine rich protein 1 Neighboring gene small ribosomal subunit protein eS6-like Neighboring gene neurolysin Neighboring gene small glutamine rich tetratricopeptide repeat co-chaperone beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neurotransmitter receptor transport postsynaptic membrane to endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    erbin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206153.2 → NP_001193082.1  erbin

      See identical proteins and their annotated locations for NP_001193082.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000020
      UniProtKB/TrEMBL
      A0A3Q1LS66, A0A3Q1M9R3
      Conserved Domains (4) summary
      COG4886
      Location:70 → 402
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:1281 → 1367
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00031
      Location:117 → 131
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      13529621..13659593 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005221458.5 → XP_005221515.1  erbin isoform X8

      See identical proteins and their annotated locations for XP_005221515.1

      UniProtKB/TrEMBL
      A0A3Q1MSP5, A0A3Q1N2M4
      Related
      ENSBTAP00000063548.1, ENSBTAT00000085028.2
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1212 → 1297
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00031
      Location:117 → 131
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:207 → 265
      LRR_8; Leucine rich repeat

    2. XM_024981265.2 → XP_024837033.1  erbin isoform X7

      UniProtKB/TrEMBL
      A0A3Q1MSP5
      Conserved Domains (4) summary
      COG4886
      Location:70 → 402
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:1254 → 1340
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00031
      Location:117 → 131
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]

    3. XM_059878706.1 → XP_059734689.1  erbin isoform X6

      UniProtKB/TrEMBL
      A0A3Q1LS66, A0A3Q1M9R3
      Related
      ENSBTAP00000063178.1, ENSBTAT00000069967.2

    4. XM_059878705.1 → XP_059734688.1  erbin isoform X4

      UniProtKB/TrEMBL
      A0A3Q1M9R3

    5. XM_024981262.2 → XP_024837030.1  erbin isoform X5

      UniProtKB/TrEMBL
      A0A3Q1M8M4
      Related
      ENSBTAP00000073126.1, ENSBTAT00000075419.2
      Conserved Domains (4) summary
      COG4886
      Location:70 → 402
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:1302 → 1388
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00031
      Location:117 → 131
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]

    6. XM_059878704.1 → XP_059734687.1  erbin isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M8M4, A0A3Q1NDG8
      Related
      ENSBTAP00000069530.1, ENSBTAT00000073306.2

    7. XM_024981259.2 → XP_024837027.1  erbin isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M8M4
      Related
      ENSBTAP00000066806.1, ENSBTAT00000066526.2
      Conserved Domains (4) summary
      COG4886
      Location:70 → 402
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:1342 → 1428
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00031
      Location:117 → 131
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]

    8. XM_005221451.5 → XP_005221508.1  erbin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M8M4, E1BKT3
      Related
      ENSBTAP00000000533.5, ENSBTAT00000000533.7
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1369 → 1455
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00031
      Location:117 → 131
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:207 → 265
      LRR_8; Leucine rich repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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