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    VIL1 villin 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 488522, updated on 5-Mar-2024

    Summary

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    Official Symbol
    VIL1provided by VGNC
    Official Full Name
    villin 1provided by VGNC
    Primary source
    VGNC:VGNC:48261
    See related
    Ensembl:ENSCAFG00845027330
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See VIL1 in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (25081617..25107747)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (25885686..25911804)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (24940950..24966867)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (24986923..25013216)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (24920579..24946677)

    Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 11 member 1 Neighboring gene CTD small phosphatase 1 Neighboring gene microRNA mir-26b Neighboring gene ubiquitin specific peptidase 37 Neighboring gene 60S ribosomal protein L34-like Neighboring gene CCR4-NOT transcription complex subunit 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament severing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin polymerization or depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in barbed-end actin filament capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of lamellipodium morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    villin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051841.1 Reference ROS_Cfam_1.0

      Range
      25081617..25107747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447931.1 → XP_038303859.1  villin-1

      UniProtKB/TrEMBL
      A0A8C0LP37, A0A8C0TPI9, A0A8I3PXX3
      Related
      ENSCAFP00845037780.1, ENSCAFT00845048164.1
      Conserved Domains (7) summary
      cd11288
      Location:513 → 603
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:137 → 227
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11290
      Location:17 → 121
      gelsolin_S1_like; Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins
      cd11291
      Location:619 → 715
      gelsolin_S6_like; Gelsolin sub-domain 6-like domain found in gelsolin, severin, villin, and related proteins
      cd11292
      Location:250 → 348
      gelsolin_S3_like; Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:392 → 492
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      pfam02209
      Location:792 → 826
      VHP; Villin headpiece domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049297.1 Alternate UMICH_Zoey_3.1

      Range
      24986923..25013216
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521929.1 → XP_038377857.1  villin-1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

      Range
      24920579..24946677
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038650104.1 → XP_038506032.1  villin-1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

      Range
      24940950..24966867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038585723.1 → XP_038441651.1  villin-1

      UniProtKB/TrEMBL
      A0A8C0PEC0, A0A8C0TPI9

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      25885686..25911804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_545642.6 → XP_545642.3  villin-1

      UniProtKB/TrEMBL
      A0A8C0LP37, A0A8C0TPI9, A0A8I3PXX3
      Conserved Domains (7) summary
      cd11288
      Location:513 → 603
      gelsolin_S5_like; Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins
      cd11289
      Location:137 → 227
      gelsolin_S2_like; Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins
      cd11290
      Location:17 → 121
      gelsolin_S1_like; Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins
      cd11291
      Location:619 → 715
      gelsolin_S6_like; Gelsolin sub-domain 6-like domain found in gelsolin, severin, villin, and related proteins
      cd11292
      Location:250 → 348
      gelsolin_S3_like; Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins
      cd11293
      Location:392 → 492
      gelsolin_S4_like; Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins
      pfam02209
      Location:792 → 826
      VHP; Villin headpiece domain
    Nucleotide Protein
    Heading Accession and Version

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