lmo7a LIM domain 7a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: lmo7aprovided by ZNC
Official Full Name: LIM domain 7aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030219-74
See related: Ensembl:ENSDARG00000004930 AllianceGenome:ZFIN:ZDB-GENE-030219-74
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc03h03; id:ibd5155; wu:fc03h03; si:dkey-57a22.10
Summary: Predicted to enable metal ion binding activity. Predicted to act upstream of or within regulation of cell adhesion and regulation of signaling. Is expressed in several structures, including brain; digestive system; eye; immature eye; and pericardial region. Orthologous to human LMO7 (LIM domain 7). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (21893757..21970658, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (22082888..22159886, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc03h03.x1 (e-PCR)
- UniSTS:192140

fc03h03.x1 (e-PCR)
- UniSTS:192141

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of signaling	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: LIM domain only protein 7

Names: LIM domain only 7a; lmo7

NP_001121703.1

EC 3.4.19.12

XP_009302886.1

EC 3.4.19.12

XP_009302895.1

EC 3.4.19.12

XP_009302897.1

EC 3.4.19.12

XP_021334325.1

EC 3.4.19.12

XP_021334326.1

EC 3.4.19.12

XP_021334327.1

EC 3.4.19.12

XP_021334328.1

EC 3.4.19.12

XP_021334329.1

EC 3.4.19.12

XP_021334330.1

EC 3.4.19.12

XP_021334331.1

EC 3.4.19.12

XP_021334332.1

EC 3.4.19.12

XP_021334333.1

EC 3.4.19.12

XP_021334334.1

EC 3.4.19.12

XP_021334335.1

EC 3.4.19.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001128231.1 → NP_001121703.1 LIM domain only protein 7

Status: PROVISIONAL

Source sequence(s)

CR536604

UniProtKB/TrEMBL

A0A8M1NHP5, B0UYM8

Related

ENSDARP00000027005.9, ENSDART00000009920.11

Conserved Domains (7) summary

COG3144
Location:954 → 1163

FliK; Flagellar hook-length control protein FliK [Cell motility]

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1757 → 1815

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam00307
Location:20 → 98

CH; Calponin homology (CH) domain

pfam15949
Location:733 → 880

DUF4757; Domain of unknown function (DUF4757)

cl20817
Location:1382 → 1424

GBP_C; Guanylate-binding protein, C-terminal domain

cl23720
Location:1383 → 1468

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007120.7 Reference GRCz11 Primary Assembly

Range

21893757..21970658 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009304622.3 → XP_009302897.1 LIM domain only protein 7 isoform X6

UniProtKB/TrEMBL

A0A8M3B2L7

Conserved Domains (7) summary

COG3144
Location:954 → 1163

FliK; Flagellar hook-length control protein FliK [Cell motility]

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1793 → 1851

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam00307
Location:20 → 98

CH; Calponin homology (CH) domain

pfam15949
Location:733 → 880

DUF4757; Domain of unknown function (DUF4757)

cl20817
Location:1365 → 1407

GBP_C; Guanylate-binding protein, C-terminal domain

cl23720
Location:1366 → 1451

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
XM_021478651.1 → XP_021334326.1 LIM domain only protein 7 isoform X3

UniProtKB/TrEMBL

A0A8M9QFC6

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1807 → 1865

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:733 → 881

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:809 → 1096

TOP2c; TopoisomeraseII

cl26511
Location:1379 → 1489

Neuromodulin_N; Gap junction protein N-terminal region
XM_009304611.3 → XP_009302886.1 LIM domain only protein 7 isoform X2

UniProtKB/TrEMBL

A0A8M3AVY5

Conserved Domains (7) summary

COG3144
Location:954 → 1163

FliK; Flagellar hook-length control protein FliK [Cell motility]

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1810 → 1868

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam00307
Location:20 → 98

CH; Calponin homology (CH) domain

pfam15949
Location:733 → 880

DUF4757; Domain of unknown function (DUF4757)

cl20817
Location:1382 → 1424

GBP_C; Guanylate-binding protein, C-terminal domain

cl23720
Location:1383 → 1468

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
XM_021478652.1 → XP_021334327.1 LIM domain only protein 7 isoform X4

UniProtKB/TrEMBL

A0A8M9PS15

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1805 → 1863

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:733 → 881

DUF4757; Domain of unknown function (DUF4757)

cl23720
Location:1396 → 1482

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

cl25574
Location:809 → 1096

TOP2c; TopoisomeraseII
XM_021478654.1 → XP_021334329.1 LIM domain only protein 7 isoform X7

UniProtKB/TrEMBL

A0A8M9QAP1

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1771 → 1829

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:733 → 881

DUF4757; Domain of unknown function (DUF4757)

cl23720
Location:1396 → 1482

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

cl25574
Location:809 → 1096

TOP2c; TopoisomeraseII
XM_021478650.1 → XP_021334325.1 LIM domain only protein 7 isoform X1

UniProtKB/TrEMBL

A0A8M9QJL3

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1824 → 1882

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:733 → 881

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:809 → 1096

TOP2c; TopoisomeraseII

cl26511
Location:1396 → 1506

Neuromodulin_N; Gap junction protein N-terminal region
XM_021478653.1 → XP_021334328.1 LIM domain only protein 7 isoform X5

UniProtKB/TrEMBL

A0A8M9Q4J8

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1799 → 1857

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:733 → 881

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:809 → 1096

TOP2c; TopoisomeraseII

cl26511
Location:1371 → 1481

Neuromodulin_N; Gap junction protein N-terminal region
XM_021478655.1 → XP_021334330.1 LIM domain only protein 7 isoform X8

UniProtKB/TrEMBL

A0A8M9QJL5

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:1184 → 1245

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1752 → 1810

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:733 → 881

DUF4757; Domain of unknown function (DUF4757)

cl23720
Location:1396 → 1482

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

cl25574
Location:809 → 1096

TOP2c; TopoisomeraseII
XM_021478656.1 → XP_021334331.1 LIM domain only protein 7 isoform X9

UniProtKB/TrEMBL

A0A8M9QFD0

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:991 → 1052

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1631 → 1689

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:540 → 688

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:616 → 903

TOP2c; TopoisomeraseII

cl26511
Location:1203 → 1313

Neuromodulin_N; Gap junction protein N-terminal region
XM_021478657.1 → XP_021334332.1 LIM domain only protein 7 isoform X10

UniProtKB/TrEMBL

A0A8M9PS20

Conserved Domains (5) summary

cd00136
Location:952 → 1013

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1592 → 1650

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:501 → 649

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:577 → 864

TOP2c; TopoisomeraseII

cl26511
Location:1164 → 1274

Neuromodulin_N; Gap junction protein N-terminal region
XM_021478658.1 → XP_021334333.1 LIM domain only protein 7 isoform X11

UniProtKB/TrEMBL

A0A8M9Q4K1

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:939 → 1000

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1579 → 1637

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:488 → 636

DUF4757; Domain of unknown function (DUF4757)

cl26511
Location:1151 → 1261

Neuromodulin_N; Gap junction protein N-terminal region

cl27460
Location:709 → 918

FliK; Flagellar hook-length control protein FliK [Cell motility]
XM_021478660.1 → XP_021334335.1 LIM domain only protein 7 isoform X13

UniProtKB/TrEMBL

A0A8M9QJM0

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:689 → 750

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1329 → 1387

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:239 → 386

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:253 → 601

TOP2c; TopoisomeraseII

cl26511
Location:901 → 1011

Neuromodulin_N; Gap junction protein N-terminal region
XM_021478659.1 → XP_021334334.1 LIM domain only protein 7 isoform X12

UniProtKB/TrEMBL

A0A8M9QAP5

Conserved Domains (6) summary

cd00014
Location:17 → 128

CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

cd00136
Location:699 → 760

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1339 → 1397

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam15949
Location:239 → 396

DUF4757; Domain of unknown function (DUF4757)

cl25574
Location:262 → 611

TOP2c; TopoisomeraseII

cl26511
Location:911 → 1021

Neuromodulin_N; Gap junction protein N-terminal region
XM_009304620.3 → XP_009302895.1 LIM domain only protein 7 isoform X14

UniProtKB/TrEMBL

A0A8M3B5K4

Conserved Domains (5) summary

cd00136
Location:689 → 750

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

cd08368
Location:1315 → 1373

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

pfam00307
Location:20 → 98

CH; Calponin homology (CH) domain

pfam15949
Location:238 → 385

DUF4757; Domain of unknown function (DUF4757)

cl20817
Location:887 → 929

GBP_C; Guanylate-binding protein, C-terminal domain