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    ASB14 ankyrin repeat and SOCS box containing 14 [ Canis lupus familiaris (dog) ]

    Gene ID: 607136, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ASB14provided by VGNC
    Official Full Name
    ankyrin repeat and SOCS box containing 14provided by VGNC
    Primary source
    VGNC:VGNC:38158
    See related
    Ensembl:ENSCAFG00845023178
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ASB14 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (33383368..33410033)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (33038555..33065206)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (33361952..33388842)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (32832425..32859045)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (33190899..33217541)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 12 Neighboring gene dynein axonemal heavy chain 12 Neighboring gene homeobox protein TGIF2-like Neighboring gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Neighboring gene uncharacterized LOC111091307 Neighboring gene 14-3-3 protein zeta/delta-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      33383368..33410033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038427438.1 → XP_038283366.1  ankyrin repeat and SOCS box protein 14 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (4) summary
      cd03730
      Location:447 → 503
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:166 → 197
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:60 → 147
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:119 → 335
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038427436.1 → XP_038283364.1  ankyrin repeat and SOCS box protein 14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (4) summary
      PHA02875
      Location:35 → 252
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:504 → 560
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:157 → 188
      ANK; ANK repeat [structural motif]
      cl39094
      Location:150 → 392
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038427435.1 → XP_038283363.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PHP9, A0A8C0QWC2, A0A8I3PHZ5
      Related
      ENSCAFP00845032028.1, ENSCAFT00845040899.1
      Conserved Domains (4) summary
      PHA02875
      Location:55 → 277
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:529 → 585
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:182 → 213
      ANK; ANK repeat [structural motif]
      cl39094
      Location:175 → 417
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038427437.1 → XP_038283365.1  ankyrin repeat and SOCS box protein 14 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (3) summary
      cd03730
      Location:449 → 505
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:102 → 133
      ANK; ANK repeat [structural motif]
      cl39094
      Location:95 → 337
      Ank_2; Ankyrin repeats (3 copies)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      32832425..32859045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038503151.1 → XP_038359079.1  ankyrin repeat and SOCS box protein 14 isoform X4

      Conserved Domains (4) summary
      cd03730
      Location:447 → 503
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:166 → 197
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:60 → 147
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:119 → 335
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038503149.1 → XP_038359077.1  ankyrin repeat and SOCS box protein 14 isoform X2

      Conserved Domains (4) summary
      PHA02875
      Location:35 → 252
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:504 → 560
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:157 → 188
      ANK; ANK repeat [structural motif]
      cl39094
      Location:150 → 392
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038503148.1 → XP_038359076.1  ankyrin repeat and SOCS box protein 14 isoform X1

      Conserved Domains (4) summary
      PHA02875
      Location:55 → 277
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:529 → 585
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:182 → 213
      ANK; ANK repeat [structural motif]
      cl39094
      Location:175 → 417
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038503150.1 → XP_038359078.1  ankyrin repeat and SOCS box protein 14 isoform X3

      Conserved Domains (3) summary
      cd03730
      Location:449 → 505
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:102 → 133
      ANK; ANK repeat [structural motif]
      cl39094
      Location:95 → 337
      Ank_2; Ankyrin repeats (3 copies)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      33190899..33217541
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038630261.1 → XP_038486189.1  ankyrin repeat and SOCS box protein 14 isoform X4

      Conserved Domains (4) summary
      cd03730
      Location:447 → 503
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:166 → 197
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:60 → 147
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:119 → 335
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038630259.1 → XP_038486187.1  ankyrin repeat and SOCS box protein 14 isoform X2

      Conserved Domains (4) summary
      PHA02875
      Location:35 → 252
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:504 → 560
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:157 → 188
      ANK; ANK repeat [structural motif]
      cl39094
      Location:150 → 392
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038630258.1 → XP_038486186.1  ankyrin repeat and SOCS box protein 14 isoform X1

      Conserved Domains (4) summary
      PHA02875
      Location:55 → 277
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:529 → 585
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:182 → 213
      ANK; ANK repeat [structural motif]
      cl39094
      Location:175 → 417
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038630260.1 → XP_038486188.1  ankyrin repeat and SOCS box protein 14 isoform X3

      Conserved Domains (3) summary
      cd03730
      Location:449 → 505
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:102 → 133
      ANK; ANK repeat [structural motif]
      cl39094
      Location:95 → 337
      Ank_2; Ankyrin repeats (3 copies)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      33361952..33388842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038566113.1 → XP_038422041.1  ankyrin repeat and SOCS box protein 14 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (4) summary
      cd03730
      Location:447 → 503
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:166 → 197
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:60 → 147
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:119 → 335
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038566111.1 → XP_038422039.1  ankyrin repeat and SOCS box protein 14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (4) summary
      PHA02875
      Location:35 → 252
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:504 → 560
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:157 → 188
      ANK; ANK repeat [structural motif]
      cl39094
      Location:150 → 392
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038566110.1 → XP_038422038.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PHP9, A0A8C0QWC2, A0A8I3PHZ5
      Conserved Domains (4) summary
      PHA02875
      Location:55 → 277
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:529 → 585
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:182 → 213
      ANK; ANK repeat [structural motif]
      cl39094
      Location:175 → 417
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038566112.1 → XP_038422040.1  ankyrin repeat and SOCS box protein 14 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (3) summary
      cd03730
      Location:449 → 505
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:102 → 133
      ANK; ANK repeat [structural motif]
      cl39094
      Location:95 → 337
      Ank_2; Ankyrin repeats (3 copies)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      33038555..33065206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038454984.1 → XP_038310912.1  ankyrin repeat and SOCS box protein 14 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (4) summary
      cd03730
      Location:447 → 503
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:166 → 197
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:60 → 147
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:119 → 335
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038454983.1 → XP_038310911.1  ankyrin repeat and SOCS box protein 14 isoform X2

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (4) summary
      PHA02875
      Location:35 → 252
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:504 → 560
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:157 → 188
      ANK; ANK repeat [structural motif]
      cl39094
      Location:150 → 392
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_022406561.2 → XP_022262269.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PHP9, A0A8C0QWC2, A0A8I3PHZ5
      Conserved Domains (4) summary
      PHA02875
      Location:55 → 277
      PHA02875; ankyrin repeat protein; Provisional
      cd03730
      Location:529 → 585
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:182 → 213
      ANK; ANK repeat [structural motif]
      cl39094
      Location:175 → 417
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_022406563.2 → XP_022262271.1  ankyrin repeat and SOCS box protein 14 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QWC2
      Conserved Domains (3) summary
      cd03730
      Location:449 → 505
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:102 → 133
      ANK; ANK repeat [structural motif]
      cl39094
      Location:95 → 337
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
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