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    LSS lanosterol synthase [ Canis lupus familiaris (dog) ]

    Gene ID: 491611, updated on 5-Mar-2024

    Summary

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    Official Symbol
    LSSprovided by VGNC
    Official Full Name
    lanosterol synthaseprovided by VGNC
    Primary source
    VGNC:VGNC:42851
    See related
    Ensembl:ENSCAFG00845024919
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LSS in Genome Data Viewer
    Location:
    chromosome: 31
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 31 NC_051835.1 (39120352..39143563, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 31 NC_006613.4 (38707040..38730234, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 31 NC_049252.1 (39460908..39484125, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 31 NC_049291.1 (38982033..39005248, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 31 NC_049772.1 (38942696..38965462, complement)

    Chromosome 31 - NC_051835.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis and centriole associated 1 like Neighboring gene uncharacterized LOC119867098 Neighboring gene minichromosome maintenance complex component 3 associated protein Neighboring gene chromosome 31 C21orf58 homolog Neighboring gene ybeY metalloendoribonuclease

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lanosterol synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in triterpenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lanosterol synthase
    Names
    lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
    XP_038299659.1
    XP_038374071.1
    XP_038437625.1
    XP_038502030.1
    XP_548733.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051835.1 Reference ROS_Cfam_1.0

      Range
      39120352..39143563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038443731.1 → XP_038299659.1  lanosterol synthase

      UniProtKB/TrEMBL
      A0A8C0RSJ2, A0A8I3S4Z8
      Related
      ENSCAFP00845034502.1, ENSCAFT00845044028.1
      Conserved Domains (1) summary
      TIGR01787
      Location:77 → 722
      squalene_cyclas; squalene/oxidosqualene cyclases

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049291.1 Alternate UMICH_Zoey_3.1

      Range
      38982033..39005248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038518143.1 → XP_038374071.1  lanosterol synthase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049772.1 Alternate UNSW_CanFamBas_1.0

      Range
      38942696..38965462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038646102.1 → XP_038502030.1  lanosterol synthase

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049252.1 Alternate UU_Cfam_GSD_1.0

      Range
      39460908..39484125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038581697.1 → XP_038437625.1  lanosterol synthase

      UniProtKB/TrEMBL
      A0A8C0R457, A0A8C0RSJ2, A0A8C0TBN9, A0A8P0NE01

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006613.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      38707040..38730234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_548733.6 → XP_548733.4  lanosterol synthase

      UniProtKB/TrEMBL
      A0A8C0R457, A0A8C0RSJ2, A0A8C0TBN9, A0A8P0NE01
      Conserved Domains (1) summary
      TIGR01787
      Location:77 → 722
      squalene_cyclas; squalene/oxidosqualene cyclases
    Nucleotide Protein
    Heading Accession and Version

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