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    ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 479481, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ACAP1provided by VGNC
    Official Full Name
    ArfGAP with coiled-coil, ankyrin repeat and PH domains 1provided by VGNC
    Primary source
    VGNC:VGNC:37496
    See related
    Ensembl:ENSCAFG00845021641
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ACAP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (32397200..32410802)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (32429841..32443451)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (32498439..32512044)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (32362625..32376257)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (32321395..32335005)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene neuralized E3 ubiquitin protein ligase 4 Neighboring gene uncharacterized LOC106558815 Neighboring gene potassium channel tetramerization domain containing 11 Neighboring gene transmembrane protein 95

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      32397200..32410802
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665378.1 → XP_038521306.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (5) summary
      COG0666
      Location:560 → 698
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cl28907
      Location:405 → 524
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_038665379.1 → XP_038521307.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (5) summary
      COG0666
      Location:560 → 694
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_038665380.1 → XP_038521308.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QHN8, A0A8I3PDU1
      Related
      ENSCAFP00845029929.1, ENSCAFT00845038211.1
      Conserved Domains (5) summary
      COG0666
      Location:560 → 693
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      32362625..32376257
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475489.1 → XP_038331417.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (5) summary
      COG0666
      Location:560 → 698
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cl28907
      Location:405 → 524
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_038475490.1 → XP_038331418.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (5) summary
      COG0666
      Location:560 → 694
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_038475491.1 → XP_038331419.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

      Conserved Domains (5) summary
      COG0666
      Location:560 → 693
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      32321395..32335005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038600837.1 → XP_038456765.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

    2. XM_038600838.1 → XP_038456766.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (5) summary
      COG0666
      Location:560 → 694
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_038600839.1 → XP_038456767.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

      Conserved Domains (5) summary
      COG0666
      Location:560 → 693
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      32498439..32512044
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038536655.1 → XP_038392583.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (5) summary
      COG0666
      Location:560 → 698
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cl28907
      Location:405 → 524
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_038536656.1 → XP_038392584.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (5) summary
      COG0666
      Location:560 → 694
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_038536657.1 → XP_038392585.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QHN8, A0A8I3PDU1
      Conserved Domains (5) summary
      COG0666
      Location:560 → 693
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      32429841..32443451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038514910.1 → XP_038370838.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (5) summary
      COG0666
      Location:560 → 698
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cl28907
      Location:405 → 524
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_038514919.1 → XP_038370847.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (5) summary
      COG0666
      Location:560 → 694
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_038514927.1 → XP_038370855.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0QHN8, A0A8I3PDU1
      Conserved Domains (5) summary
      COG0666
      Location:560 → 693
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:575 → 602
      ANK; ANK repeat [structural motif]
      cd08852
      Location:405 → 524
      ArfGap_ACAP1; ArfGAP domain of ACAP1 (ArfGAP with Coiled-coil, ANK repeat and PH domains 1)
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
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