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    UNC45B unc-45 myosin chaperone B [ Canis lupus familiaris (dog) ]

    Gene ID: 480606, updated on 5-Mar-2024

    Summary

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    Official Symbol
    UNC45Bprovided by VGNC
    Official Full Name
    unc-45 myosin chaperone Bprovided by VGNC
    Primary source
    VGNC:VGNC:48138
    See related
    Ensembl:ENSCAFG00845010061
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See UNC45B in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (39001372..39030073, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (37413649..37442109, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (38157973..38186674, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (37785169..37813631, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (38070500..38099164, complement)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene schlafen family member 12 Neighboring gene schlafen family member 5 Neighboring gene notchless homolog 1 Neighboring gene fibronectin type III domain containing 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Hsp90 protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chaperone-mediated protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein unc-45 homolog B
    Names
    unc-45 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      39001372..39030073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038677317.1 → XP_038533245.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    2. XM_038677320.1 → XP_038533248.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    3. XM_038677318.1 → XP_038533246.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Related
      ENSCAFP00845013862.1, ENSCAFT00845017786.1
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    4. XM_038677319.1 → XP_038533247.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      37785169..37813631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038486278.1 → XP_038342206.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    2. XM_038486281.1 → XP_038342209.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    3. XM_038486279.1 → XP_038342207.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    4. XM_038486280.1 → XP_038342208.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      38070500..38099164 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038612070.1 → XP_038467998.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    2. XM_038612073.1 → XP_038468001.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    3. XM_038612071.1 → XP_038467999.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    4. XM_038612072.1 → XP_038468000.1  protein unc-45 homolog B

      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      38157973..38186674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038548099.1 → XP_038404027.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2

    2. XM_038548102.1 → XP_038404030.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2

    3. XM_038548100.1 → XP_038404028.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2

    4. XM_038548101.1 → XP_038404029.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37413649..37442109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_537726.7 → XP_537726.2  protein unc-45 homolog B

      See identical proteins and their annotated locations for XP_537726.2

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    2. XM_005624800.4 → XP_005624857.1  protein unc-45 homolog B

      See identical proteins and their annotated locations for XP_005624857.1

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    3. XM_005624799.4 → XP_005624856.1  protein unc-45 homolog B

      See identical proteins and their annotated locations for XP_005624856.1

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central

    4. XM_022423303.2 → XP_022279011.1  protein unc-45 homolog B

      UniProtKB/TrEMBL
      A0A8C0NYA3, A0A8C0R0X0, A0A8I3N3D2
      Conserved Domains (4) summary
      TIGR00990
      Location:3 → 134
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central
    Nucleotide Protein
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