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    marf1 meiosis regulator and mRNA stability factor 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 733745, updated on 25-Apr-2024

    Summary

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    Official Symbol
    marf1provided by Xenbase
    Official Full Name
    meiosis regulator and mRNA stability factor 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-990483
    See related
    Ensembl:ENSXETG00000005529
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    lkap; kiaa0430; Limkain-b1
    Orthologs
    human mouse all
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    Genomic context

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    See marf1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (34093288..34125229)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (28183788..28215611)

    Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 11 Neighboring gene nudE neurodevelopment protein 1 Neighboring gene bMERB domain containing 1 Neighboring gene posterior protein-like Neighboring gene pyridoxal-dependent decarboxylase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genome of the Western clawed frog Xenopus tropicalis. Hellsten U, et al. Science, 2010 Apr 30. PMID 20431018, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables CCR4-NOT complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within oogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    meiosis regulator and mRNA stability factor 1
    Names
    Meiosis arrest female protein 1 homolog
    limkain b1 (lkap)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126066.1 → NP_001119538.1  meiosis regulator and mRNA stability factor 1

      See identical proteins and their annotated locations for NP_001119538.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166346
      UniProtKB/Swiss-Prot
      B2GUN4
      UniProtKB/TrEMBL
      A0A6I8QPH2
      Related
      ENSXETP00000076982.2, ENSXETT00000096746.2
      Conserved Domains (12) summary
      cd09977
      Location:864 → 925
      LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
      cd09978
      Location:992 → 1062
      LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
      cd09979
      Location:1088 → 1159
      LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
      cd09980
      Location:1164 → 1235
      LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
      cd09981
      Location:1248 → 1318
      LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
      cd09982
      Location:1324 → 1394
      LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
      cd09983
      Location:1400 → 1472
      LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
      cd09984
      Location:1475 → 1550
      LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
      cd10910
      Location:339 → 481
      limkain_b1_N_like; N-terminal LabA-like domain of limkain b1 and similar proteins
      COG0724
      Location:501 → 681
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12256
      Location:775 → 863
      RRM2_LKAP; RNA recognition motif 2 in Limkain-b1 (LKAP) and similar proteins
      pfam11608
      Location:497 → 582
      Limkain-b1; Limkain b1

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      34093288..34125229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031892721.1 → XP_031748581.1  meiosis regulator and mRNA stability factor 1 isoform X5

      UniProtKB/TrEMBL
      A0A6I8QPH2, A0A8J1IVS3
      Conserved Domains (11) summary
      cd09977
      Location:865 → 926
      LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
      cd09978
      Location:993 → 1063
      LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
      cd09979
      Location:1089 → 1160
      LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
      cd09980
      Location:1165 → 1236
      LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
      cd09981
      Location:1249 → 1319
      LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
      cd09982
      Location:1325 → 1395
      LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
      cd09983
      Location:1401 → 1463
      LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
      COG0724
      Location:502 → 682
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd10910
      Location:340 → 462
      PIN_limkain_b1_N_like; N-terminal LabA-like PIN domain of limkain b1 and similar proteins
      pfam11608
      Location:498 → 583
      Limkain-b1; Limkain b1
      cd12256
      Location:776 → 864
      RRM2_LKAP; RNA recognition motif 2 (RRM2) found in Limkain-b1 (LKAP) and similar proteins

    2. XM_012970506.3 → XP_012825960.2  meiosis regulator and mRNA stability factor 1 isoform X3

      UniProtKB/TrEMBL
      A0A6I8QPH2, A0A6I8RDL4
      Related
      ENSXETP00000078998.2, ENSXETT00000078382.2
      Conserved Domains (12) summary
      cd09978
      Location:966 → 1036
      LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
      cd09979
      Location:1062 → 1133
      LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
      cd09980
      Location:1138 → 1209
      LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
      cd09981
      Location:1222 → 1292
      LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
      cd09982
      Location:1298 → 1368
      LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
      cd09983
      Location:1374 → 1446
      LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
      cd09984
      Location:1449 → 1524
      LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
      COG0724
      Location:502 → 682
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd10910
      Location:340 → 462
      PIN_limkain_b1_N_like; N-terminal LabA-like PIN domain of limkain b1 and similar proteins
      pfam11608
      Location:498 → 583
      Limkain-b1; Limkain b1
      cd12256
      Location:776 → 864
      RRM2_LKAP; RNA recognition motif 2 (RRM2) found in Limkain-b1 (LKAP) and similar proteins
      cl14879
      Location:869 → 899
      LabA_like_C; C-terminal domain of LabA_like proteins

    3. XM_031892720.1 → XP_031748580.1  meiosis regulator and mRNA stability factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A6I8QPH2, A0A8J1IV01
      Conserved Domains (12) summary
      cd09977
      Location:864 → 925
      LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
      cd09978
      Location:992 → 1062
      LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
      cd09979
      Location:1088 → 1159
      LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
      cd09980
      Location:1164 → 1235
      LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
      cd09981
      Location:1248 → 1318
      LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
      cd09982
      Location:1324 → 1394
      LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
      cd09983
      Location:1400 → 1472
      LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
      cd09984
      Location:1475 → 1550
      LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
      COG0724
      Location:501 → 681
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd10910
      Location:340 → 462
      PIN_limkain_b1_N_like; N-terminal LabA-like PIN domain of limkain b1 and similar proteins
      pfam11608
      Location:497 → 582
      Limkain-b1; Limkain b1
      cd12256
      Location:775 → 863
      RRM2_LKAP; RNA recognition motif 2 (RRM2) found in Limkain-b1 (LKAP) and similar proteins

    4. XM_012970505.3 → XP_012825959.2  meiosis regulator and mRNA stability factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A6I8QPH2, A0A6I8QUA5
      Conserved Domains (12) summary
      cd09977
      Location:865 → 926
      LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
      cd09978
      Location:993 → 1063
      LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
      cd09979
      Location:1089 → 1160
      LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
      cd09980
      Location:1165 → 1236
      LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
      cd09981
      Location:1249 → 1319
      LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
      cd09982
      Location:1325 → 1395
      LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
      cd09983
      Location:1401 → 1473
      LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
      cd09984
      Location:1476 → 1551
      LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
      COG0724
      Location:502 → 682
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd10910
      Location:340 → 462
      PIN_limkain_b1_N_like; N-terminal LabA-like PIN domain of limkain b1 and similar proteins
      pfam11608
      Location:498 → 583
      Limkain-b1; Limkain b1
      cd12256
      Location:776 → 864
      RRM2_LKAP; RNA recognition motif 2 (RRM2) found in Limkain-b1 (LKAP) and similar proteins

    5. XM_012970507.3 → XP_012825961.2  meiosis regulator and mRNA stability factor 1 isoform X4

      UniProtKB/TrEMBL
      A0A6I8QPH2, A0A8J0SNL6
      Conserved Domains (12) summary
      cd09977
      Location:700 → 761
      LOTUS_1_Limkain_b1; The first LOTUS domain on Limkain b1(LKAP)
      cd09978
      Location:828 → 898
      LOTUS_2_Limkain_b1; The second LOTUS domain on Limkain b1(LKAP)
      cd09979
      Location:924 → 995
      LOTUS_3_Limkain_b1; The third LOTUS domain on Limkain b1(LKAP)
      cd09980
      Location:1000 → 1071
      LOTUS_4_Limkain_b1; The fourth LOTUS domain on Limkain b1(LKAP)
      cd09981
      Location:1084 → 1154
      LOTUS_5_Limkain_b1; The fifth LOTUS domain on Limkain b1(LKAP)
      cd09982
      Location:1160 → 1230
      LOTUS_6_Limkain_b1; The sixth LOTUS domain on Limkain b1(LKAP)
      cd09983
      Location:1236 → 1308
      LOTUS_7_Limkain_b1; The seventh LOTUS domain on Limkain b1(LKAP)
      cd09984
      Location:1311 → 1386
      LOTUS_8_Limkain_b1; The eighth LOTUS domain on Limkain b1(LKAP)
      COG0724
      Location:337 → 517
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd10910
      Location:175 → 297
      PIN_limkain_b1_N_like; N-terminal LabA-like PIN domain of limkain b1 and similar proteins
      pfam11608
      Location:333 → 418
      Limkain-b1; Limkain b1
      cd12256
      Location:611 → 699
      RRM2_LKAP; RNA recognition motif 2 (RRM2) found in Limkain-b1 (LKAP) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B2GUN4.1 GenPept UniProtKB/Swiss-Prot:B2GUN4

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