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    KNG1 kininogen 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 478666, updated on 5-Mar-2024

    Summary

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    Official Symbol
    KNG1provided by VGNC
    Official Full Name
    kininogen 1provided by VGNC
    Primary source
    VGNC:VGNC:53466
    See related
    Ensembl:ENSCAFG00845021120
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human all
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    Genomic context

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    See KNG1 in Genome Data Viewer
    Location:
    chromosome: 34
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 34 NC_051838.1 (19199856..19229431)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 34 NC_006616.4 (23373992..23403581)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 34 NC_049255.1 (19460203..19488753)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 34 NC_049294.1 (19231763..19260578)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 34 NC_049775.1 (19231843..19260884)

    Chromosome 34 - NC_051838.1Genomic Context describing neighboring genes Neighboring gene fetuin B Neighboring gene histidine rich glycoprotein Neighboring gene small nucleolar RNA SNORD2 Neighboring gene small nucleolar RNA SNORA81 Neighboring gene eukaryotic translation initiation factor 4A2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Resistin impairs endothelium-dependent dilation to bradykinin, but not acetylcholine, in the coronary circulation. Dick GM, et al. Am J Physiol Heart Circ Physiol, 2006 Dec. PMID 16905596

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in blood microparticle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kininogen-1
    Names
    bradykinin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051838.1 Reference ROS_Cfam_1.0

      Range
      19199856..19229431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038445822.1 → XP_038301750.1  kininogen-1

      UniProtKB/TrEMBL
      A0A8C0Z0E7, A0A8I3PBR7, A0A8I3PCU2, A0A8P0TEU3
      Related
      ENSCAFP00845029426.1, ENSCAFT00845037560.1
      Conserved Domains (2) summary
      smart00043
      Location:264 → 371
      CY; Cystatin-like domain
      pfam00031
      Location:144 → 236
      Cystatin; Cystatin domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049294.1 Alternate UMICH_Zoey_3.1

      Range
      19231763..19260578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038520019.1 → XP_038375947.1  kininogen-1

      Conserved Domains (2) summary
      smart00043
      Location:264 → 371
      CY; Cystatin-like domain
      pfam00031
      Location:144 → 236
      Cystatin; Cystatin domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049775.1 Alternate UNSW_CanFamBas_1.0

      Range
      19231843..19260884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038648061.1 → XP_038503989.1  kininogen-1

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049255.1 Alternate UU_Cfam_GSD_1.0

      Range
      19460203..19488753
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038583644.1 → XP_038439572.1  kininogen-1

      UniProtKB/TrEMBL
      A0A8C0Z0E7, A0A8I3PBR7, A0A8I3PCU2, A0A8P0TEU3
      Conserved Domains (2) summary
      smart00043
      Location:264 → 371
      CY; Cystatin-like domain
      pfam00031
      Location:144 → 236
      Cystatin; Cystatin domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006616.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      23373992..23403581
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_535836.7 → XP_535836.1  kininogen-1

      UniProtKB/TrEMBL
      A0A8C0Z0E7, A0A8I3PBR7, A0A8I3PCU2, A0A8P0TEU3
      Conserved Domains (2) summary
      smart00043
      Location:264 → 371
      CY; Cystatin-like domain
      pfam00031
      Location:144 → 236
      Cystatin; Cystatin domain
    Nucleotide Protein
    Heading Accession and Version

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