|
| Status |
Public on Jan 09, 2013 |
| Title |
Corticosterone regulation of mRNAs and and corresponding RU486 antagonism in astrocytes in vitro |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of mRNA gene expression changes mediated by natural glucocorticoid ligand corticosterone in mouse cortical primary astrocyte cultures; also, parallel analysis of RU486 (mifepristone) antagonism of corticosterone-mediated mRNA changes.
|
| |
|
| Overall design |
Total RNA obtained from astrocyte cultures subjected to 2, 4, or 6 hours of (1) 100nM corticosterone alone, (2) 500nM RU486 alone, or (3) 100nM corticosterone + 500nM RU486 exposure compared to vehicle control astrocyte cultures.
|
| |
|
| Contributor(s) |
Carter BS, Thompson RC |
| Citation(s) |
23110767 |
| Submission date |
Jul 11, 2012 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Bradley S Carter |
| E-mail(s) |
bscarter@umich.edu
|
| Organization name |
University of Michigan
|
| Department |
Molecular and Behavioral Neuroscience Institute
|
| Lab |
Thompson
|
| Street address |
109 Zina PItcher Place
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
|
| Samples (36)
|
|
| Relations |
| BioProject |
PRJNA170446 |
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