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    IRF5 interferon regulatory factor 5 [ Canis lupus familiaris (dog) ]

    Gene ID: 482264, updated on 5-Mar-2024

    Summary

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    Official Symbol
    IRF5provided by VGNC
    Official Full Name
    interferon regulatory factor 5provided by VGNC
    Primary source
    VGNC:VGNC:42094
    See related
    Ensembl:ENSCAFG00845021435
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (7490116..7500966, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (7411116..7421966, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (7582360..7592901, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (7695157..7706007, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (7437183..7448035, complement)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867510 Neighboring gene transportin 3 Neighboring gene ATP synthase F(0) complex subunit C3, mitochondrial-like Neighboring gene kielin cysteine rich BMP regulator Neighboring gene collagen alpha-1(VII) chain-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon regulatory factor 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      7490116..7500966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686186.1 → XP_038542114.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    2. XM_038686184.1 → XP_038542112.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    3. XM_038686182.1 → XP_038542110.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Related
      ENSCAFP00845029648.1, ENSCAFT00845037838.1
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    4. XM_038686183.1 → XP_038542111.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    5. XM_038686181.1 → XP_038542109.1  interferon regulatory factor 5 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:242 → 399
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:339 → 522
      IRF-3; Interferon-regulatory factor 3

    6. XM_038686180.1 → XP_038542108.1  interferon regulatory factor 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LD35, A0A8C0S8H2, A0A8I3PFT0
      Related
      ENSCAFP00845029757.1, ENSCAFT00845037973.1
      Conserved Domains (3) summary
      PHA03247
      Location:257 → 414
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:354 → 537
      IRF-3; Interferon-regulatory factor 3

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      7695157..7706007 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038494270.1 → XP_038350198.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    2. XM_038494269.1 → XP_038350197.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    3. XM_038494267.1 → XP_038350195.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    4. XM_038494268.1 → XP_038350196.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    5. XM_038494266.1 → XP_038350194.1  interferon regulatory factor 5 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:242 → 399
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:339 → 522
      IRF-3; Interferon-regulatory factor 3

    6. XM_038494265.1 → XP_038350193.1  interferon regulatory factor 5 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:257 → 414
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:354 → 537
      IRF-3; Interferon-regulatory factor 3

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      7437183..7448035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038620499.1 → XP_038476427.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    2. XM_038620498.1 → XP_038476426.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    3. XM_038620496.1 → XP_038476424.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    4. XM_038620497.1 → XP_038476425.1  interferon regulatory factor 5 isoform X3

      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    5. XM_038620495.1 → XP_038476423.1  interferon regulatory factor 5 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:242 → 399
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:339 → 522
      IRF-3; Interferon-regulatory factor 3

    6. XM_038620494.1 → XP_038476422.1  interferon regulatory factor 5 isoform X1

      Conserved Domains (3) summary
      PHA03247
      Location:257 → 414
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:354 → 537
      IRF-3; Interferon-regulatory factor 3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

      Range
      7582360..7592901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038556565.1 → XP_038412493.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    2. XM_038556563.1 → XP_038412491.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    3. XM_038556564.1 → XP_038412492.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    4. XM_038556562.1 → XP_038412490.1  interferon regulatory factor 5 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:242 → 399
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:339 → 522
      IRF-3; Interferon-regulatory factor 3

    5. XM_038556561.1 → XP_038412489.1  interferon regulatory factor 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LD35, A0A8C0S8H2, A0A8I3PFT0
      Conserved Domains (3) summary
      PHA03247
      Location:257 → 414
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:354 → 537
      IRF-3; Interferon-regulatory factor 3

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      7411116..7421966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014119061.3 → XP_013974536.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    2. XM_014119060.3 → XP_013974535.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    3. XM_038435880.1 → XP_038291808.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    4. XM_038435891.1 → XP_038291819.1  interferon regulatory factor 5 isoform X3

      UniProtKB/TrEMBL
      A0A8C0L8M5, A0A8C0PKM3, A0A8I3PFI4, A0A8P0S7Q5
      Conserved Domains (3) summary
      PHA03247
      Location:171 → 328
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:16 → 121
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:268 → 451
      IRF-3; Interferon-regulatory factor 3

    5. XM_005628408.4 → XP_005628465.1  interferon regulatory factor 5 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:242 → 399
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:339 → 522
      IRF-3; Interferon-regulatory factor 3

    6. XM_014119058.3 → XP_013974533.1  interferon regulatory factor 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LD35, A0A8C0S8H2, A0A8I3PFT0
      Conserved Domains (3) summary
      PHA03247
      Location:257 → 414
      PHA03247; large tegument protein UL36; Provisional
      pfam00605
      Location:102 → 207
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:354 → 537
      IRF-3; Interferon-regulatory factor 3
    Nucleotide Protein
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