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    LOC656403 paralytic B [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 656403, updated on 15-Apr-2024

    Summary

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    Gene symbol
    LOC656403
    Gene description
    paralytic B
    Locus tag
    TcasGA2_TC004749
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Also known as
    Para
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    Genomic context

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    See LOC656403 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 10 NC_087403.1 (7026109..7043460)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LGX NC_007416.3 (6354039..6371251)

    Chromosome 10 - NC_087403.1Genomic Context describing neighboring genes Neighboring gene receptor type guanylyl cyclase-like Neighboring gene serine protease P52 Neighboring gene kinesin-like protein KIF11-B Neighboring gene kinesin 5B Neighboring gene masquerade

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    paralytic B
    Names
    AUGUSTUS-3.0.2_04749
    GLEAN_04749
    Sodium channel protein para-like Protein
    voltage-gated sodium channel 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001165909.1 → NP_001159381.1  paralytic B

      See identical proteins and their annotated locations for NP_001159381.1

      Status: PROVISIONAL

      Source sequence(s)
      GQ202025
      UniProtKB/TrEMBL
      A0A7U3PEA2, C9D7C8
      Conserved Domains (5) summary
      cd13433
      Location:1546 → 1598
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1303 → 1554
      Ion_trans; Ion transport protein
      pfam06512
      Location:1040 → 1281
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:520 → 645
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1865 → 1915
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087403.1 Reference icTriCast1.1 Primary Assembly

      Range
      7026109..7043460
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015982131.2 → XP_015837617.1  paralytic B isoform X2

      UniProtKB/TrEMBL
      D6W7W6
      Conserved Domains (5) summary
      cd13433
      Location:1539 → 1591
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1296 → 1547
      Ion_trans; Ion transport protein
      pfam06512
      Location:1033 → 1274
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:520 → 645
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1858 → 1908
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    2. XM_064359198.1 → XP_064215268.1  paralytic B isoform X1

    3. XM_064359200.1 → XP_064215270.1  paralytic B isoform X4

    4. XM_064359201.1 → XP_064215271.1  paralytic B isoform X5

    5. XM_064359199.1 → XP_064215269.1  paralytic B isoform X3

    6. XM_064359202.1 → XP_064215272.1  paralytic B isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases