Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 885

1.

Renal circadian rhythm dysregulation in lupus nephritis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing
Platforms:
GPL21103 GPL6885
117 Samples
Download data: IDAT, TXT
Series
Accession:
GSE131894
ID:
200131894
2.

Renal circadian rhythm dysregulation in lupus nephritis [array]

(Submitter supplied) This study examines the circadian gene expression of whole kidneys of young and nephritic NZB/W F1 mice
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
48 Samples
Download data: IDAT, TXT
Series
Accession:
GSE131892
ID:
200131892
3.

Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice

(Submitter supplied) Chronic stress induces adaptive changes in the brain via the cumulative action of glucocorticoids, which is associated with mood disorders. Here we show that repeated daily five-minute restraint resolves pre-existing stress-induced depressive-like behavior in mice. Repeated injection of glucocorticoids in low doses mimics the anti-depressive effects of short-term stress. Repeated exposure to short-term stress and injection of glucocorticoids activate neurons in largely overlapping regions of the brain, as shown by c-Fos staining, and reverse distinct stress-induced gene expression profiles. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
6 Samples
Download data: TXT, XLSX
Series
Accession:
GSE183624
ID:
200183624
4.

Whole genome profiling of murine lymphocytes and statistical validation of a panel of immune molecules to predict vaccine efficacy against Mycobacterium tuberculosis

(Submitter supplied) Transcriptional profiling of splenic lymphocytes derived from vaccinated mice, and ex-vivo exposed to M.tb.-infected macrophages in culture. Splenocytes from mice innoculated with Mycobacterium bovis BCG Pasteur (PAS), or M. bovis BCG Copenhagen (SSI), or heat killed BCG SSI (HK), or uninfected control, were ex vivo co-cultured with mouse bone marrow macrophages previously infected with M. tb.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
11 Samples
Download data: TXT
Series
Accession:
GSE135592
ID:
200135592
5.

Small intestinal tissue and epithelial regeneration after 12 Gy whole-body irradiation of C57BL/6 wild type mice

(Submitter supplied) C57BL/6 wild type mice were exposed to 12 Gy whole-body irradiation. Before irradiation (t=0) and at t=24, 48 and 96 hours after irradiation, mice (n=10 per time point) were euthanized. From n=5 mice per time point RNA was isolated from small-intestinal (jejunum) tissue, from n=5 mice per time point RNA was isolated from EDTA-isolated epithelial cells from small-intestinal tissue (jejunum).
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
40 Samples
Download data: IDAT, TXT
Series
Accession:
GSE179777
ID:
200179777
6.

Genome-wide analysis for joint tissues of Fas (ligand) mutant mice during autoantibody induced arthritis

(Submitter supplied) Analysis on gene expression between RA-induced WT, Fas^lpr/lpr, and Fas^gld/gld mice. Data shows different expression pattern between Fas^gld/gld joint and Fas^lpr/lpr(or WT) mice. The reseults indicate sFasL-dependent, but Fas-independent gene expression during AIA
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
3 Samples
Download data: IDAT
Series
Accession:
GSE110343
ID:
200110343
7.

Hemispheric lateralization of gene expression profile in stressed mice

(Submitter supplied) Chronic stress increases the risk of emotional disorders by altering brain structure and function. Patients with post-traumatic stress disorder (PTSD) or depressions show activity difference between the two hemispheres in the prefrontal cortex (PFC) but molecular targets associated with this laterality remains unclear. Here, we reveal that chronic social defeats later gene-expression profile differentially between the left and right medial prefrontal cortices (mPFC) in mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
16 Samples
Download data: TXT
Series
Accession:
GSE114224
ID:
200114224
8.

Regulation of adipocyte differentiation by IRF3

(Submitter supplied) The hypothesis tested is that IRF3 regulates adipogenesis and adipocyte function. Global gene expression of IRF3 wildtype (WT) and knockout (KO) adipocytes at different days during differentiation was compared. The results provide evidence on how IRF3 controls PPARg -regulated adipogenic program thereby regulate adipocyte differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE172491
ID:
200172491
9.

Gene expression profiling of Vglut2 neurons in the vestibular nucleus (VN)

(Submitter supplied) Vestibular nuclei (VN) are critical for the processing of movement input, and motion-induced activation of VN neurons recapitulates MS-related signs. However, the genetic identity of VN neurons mediating MS-related autonomic and aversive responses remains unknown. Here, we identify diferent markers of glutamatergic vestibular neuronal populations using the RiboTag apparoach.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
6 Samples
Download data: TXT
Series
Accession:
GSE167672
ID:
200167672
10.

Brain Genexpession of a mouse modle of Sepsis-associated encephalopathy (SAE)

(Submitter supplied) Sepsis-associated encephalopathy (SAE) is a major and frequent complication in patients with sepsis resulting in delirium and premature death. Sepsis survivors commonly suffer from long-term cognitive impairment causing immense burden on patients, caregivers, and economic health systems. Underlying pathophysiology of SAE related cognitive deficits is largely unresolved, Thus treatment options are missing. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
16 Samples
Download data: IDAT, TXT
Series
Accession:
GSE167610
ID:
200167610
11.

Genome-wide analysis of genes regulated by AhR

(Submitter supplied) Analysis of gene expression changes due to lack of AhR in NK cells. Cytokine activated NK cells upregulate expression of AhR and display homeostatic and functional defects. Goal of this study was to identify gene expression changes associated with NK cell activity.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
8 Samples
Download data: TXT
Series
Accession:
GSE161923
ID:
200161923
12.

Interception targets of Angelica Gigas Nakai root extract vs. pyranocoumarins in prostate early lesions and neuroendocrine carcinomas in TRAMP mice

(Submitter supplied) We reported efficacy of Angelica gigas Nakai (AGN) root ethanol extract and equimolar decursin (D)/decursinol angelate (DA) through daily gavage starting at 8 weeks of age (WOA) to male transgenic adenocarcinoma of mouse prostate (TRAMP) mice such that these modalities suppressed precancerous epithelial lesions in their dorsolateral prostate (DLP) to similar extent, but AGN extract was better than the D/DA mixture at promoting the survival of mice bearing prostate neuroendocrine carcinomas (NECa) to 28 WOA (Tang et al, Cancer Prev Res 2015). more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
16 Samples
Download data: IDAT, TXT
Series
Accession:
GSE164854
ID:
200164854
13.

Overexpression of A kinase interacting protein 1 attenuates myocardial ischemia / reperfusion injury, but does not influence heart failure development

(Submitter supplied) Aims A kinase interacting protein 1 (AKIP1) stimulates physiological growth in cultured cardiomyocytes and attenuates ischemia / reperfusion (I/R) injury in ex vivo perfused hearts. We aimed to determine whether AKIP1 modulates the cardiac response to acute and chronic cardiac stress in vivo. Methods and results Transgenic mice with cardiac-specific overexpression of AKIP1 (AKIP1-TG) were created. AKIP1-TG mice and their wild type (WT) littermates displayed similar cardiac structure and function. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
16 Samples
Download data: TXT
Series
Accession:
GSE83472
ID:
200083472
14.

Lifelong Reduction in Complex IV Induces Tissue Specific Metabolic Effects But Does Not Reduce Lifespan or Healthspan in Mice

(Submitter supplied) Loss of SURF1, a Complex IV assembly protein, was reported to increase lifespan in mice despite dramatically lower cytochrome oxidase (COX) activity. Consistent with this, our previous studies found advantageous changes in metabolism (reduced adiposity, increased insulin sensitivity and mitochon-drial biogenesis) in Surf1-/- mice. The lack of deleterious phenotypes in Surf1-/- mice is contrary to the hypothesis that mitochondrial dysfunction contributes to aging. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
44 Samples
Download data: TXT
Series
Accession:
GSE107191
ID:
200107191
15.

Gene expression profiles of melanoma tumor samples from patients treated with checkpoint inhibitors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array
Platforms:
GPL6885 GPL10558
22 Samples
Download data
Series
Accession:
GSE122222
ID:
200122222
16.

Gene expression profiles of melanoma tumor samples from patients treated with checkpoint inhibitors (mouse)

(Submitter supplied) Checkpoint inhibitors have improved outcomes for patients with metastatic melanoma, but primary or acquired resistance often occurs. We used the mouse melanoma cell line B16, originally derived from C57BL6 mice, to model changes in tumor cell gene expression that occur with acquired resistance to checkpoint inhibitors. B16 cells used were engineered to express the fluorescent marker tdTomato, to assist monitoring and cell sorting. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
12 Samples
Download data: TXT
Series
Accession:
GSE122221
ID:
200122221
17.

The Longevity Gene mIndy (I’m Not Dead, Yet) Affects Blood Pressure Through Sympathoadrenal Mechanisms

(Submitter supplied) Reduced expression of the plasma-membrane citrate-transporter INDY (acronym I’m Not Dead, Yet) extends life span in lower organisms. Deletion of the mammalian Indy (mIndy) gene in rodents improves metabolism via mechanisms akin to caloric restriction, known to lower blood pressure (BP) by sympathoadrenal inhibition. We hypothesized that mIndy deletion attenuates sympathoadrenal support of BP. mINDY-knockout (KO) mice were monitored using radiotelemetry; autonomic cardiovascular control was assessed by pharmacological testing, spectral analysis, urine catecholamines and adrenal transcriptome analysis. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
11 Samples
Download data: TXT
Series
Accession:
GSE124886
ID:
200124886
18.

Gene expression during synaptic regeneration between cochlear hair cells and neurons

(Submitter supplied) Significant changes in the expression of synaptic and inflammatory genes were observed early after damage, during regeneration of the fibers and synapses, and after completion of in vitro regeneration between afferent neurons and cochlear hair cells.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
38 Samples
Download data: CSV
Series
Accession:
GSE130495
ID:
200130495
19.

Transcriptional characterization of hippocampi from novel preclinical model of drug-resistant epilepsy

(Submitter supplied) A novel model of drug-resistant epilepsy based on the selection of mice treated with phenytoin (PHT) in the 6 Hz seizure model was developed. It leads to the identification of subpopulations of drug-responder and non-responder mice. Transcriptional characterization of the hippocampi from these 2 sub-populations was performed and compared. No significant difference has been observed between the 2 sample groups.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
30 Samples
Download data: TXT
Series
Accession:
GSE157797
ID:
200157797
20.

MARCH1 regulates anti-malarial immunity through interferon signaling and T cell activation

(Submitter supplied) Malaria infection induces complex and diverse immune responses, including impairment of dendritic cell (DC) function and immune suppression that may contribute to the low vaccination antibody titers to some antigens in endemic populations. To elucidate the mechanisms underlying host-parasite interaction, we performed a genetic screen during early Plasmodium yoelii infection and identified a large number of interacting host and parasite genes/loci after trans-species expression quantitative trait loci (Ts-eQTL) analysis. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
69 Samples
Download data: TXT
Series
Accession:
GSE119944
ID:
200119944
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GPL6885[RGSE]|query=1|qty=17|blobid=MCID_6144bae55161e1587716fdd6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center