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    ANKHD1 ankyrin repeat and KH domain containing 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 612748, updated on 22-Jan-2024

    Summary

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    Gene symbol
    ANKHD1
    Gene description
    ankyrin repeat and KH domain containing 1
    See related
    Ensembl:ENSCAFG00845001622
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (36073948..36191878)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (32656633..32775478)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (34746141..34864980)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (33125806..33244752)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (33993175..34112289)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102154811 Neighboring gene solute carrier family 4 member 9 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene 60S ribosomal protein L7a-like Neighboring gene U6 spliceosomal RNA Neighboring gene eukaryotic translation initiation factor 4E binding protein 3 Neighboring gene steroid receptor RNA activator 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and KH domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204095.1 → NP_001191024.1  ankyrin repeat and KH domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000373
      UniProtKB/TrEMBL
      A0A8C0JQB1, A0A8C0ME53, A0A8I3MIA7
      Related
      ENSCAFP00845002262.1, ENSCAFT00845002842.1
      Conserved Domains (7) summary
      cd00105
      Location:1695 → 1757
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd00204
      Location:362 → 486
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam05672
      Location:775 → 860
      MAP7; MAP7 (E-MAP-115) family
      pfam12796
      Location:271 → 360
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:369 → 420
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:401 → 430
      ANK; ANK repeat [structural motif]
      cl09111
      Location:809 → 847
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      36073948..36191878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038657875.1 → XP_038513803.1  ankyrin repeat and KH domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0JQB1, A0A8C0M8E9, A0A8P0TCN1
      Conserved Domains (7) summary
      PHA03095
      Location:206 → 526
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:1797 → 2198
      PHA03247; large tegument protein UL36; Provisional
      PRK03918
      Location:793 → 879
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:401 → 430
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:534 → 643
      Ank_2; Ankyrin repeats (3 copies)
      cd22503
      Location:1713 → 1795
      KH-I_ANKHD1; type I K homology (KH) RNA-binding domain found in ankyrin repeat and KH domain-containing protein 1 (ANKHD1) and similar proteins
      cl39094
      Location:1138 → 1426
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038657876.1 → XP_038513804.1  ankyrin repeat and KH domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JQB1
      Conserved Domains (7) summary
      PHA03095
      Location:206 → 526
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:1797 → 2198
      PHA03247; large tegument protein UL36; Provisional
      PRK03918
      Location:793 → 879
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:401 → 430
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:534 → 643
      Ank_2; Ankyrin repeats (3 copies)
      cd22503
      Location:1713 → 1795
      KH-I_ANKHD1; type I K homology (KH) RNA-binding domain found in ankyrin repeat and KH domain-containing protein 1 (ANKHD1) and similar proteins
      cl39094
      Location:1138 → 1426
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038657877.1 → XP_038513805.1  ankyrin repeat and KH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQB1, A0A8P0N8F7
      Conserved Domains (7) summary
      PHA03095
      Location:206 → 526
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:1778 → 2179
      PHA03247; large tegument protein UL36; Provisional
      PRK03918
      Location:774 → 860
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:401 → 430
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:534 → 624
      Ank_2; Ankyrin repeats (3 copies)
      cd22503
      Location:1694 → 1776
      KH-I_ANKHD1; type I K homology (KH) RNA-binding domain found in ankyrin repeat and KH domain-containing protein 1 (ANKHD1) and similar proteins
      cl39094
      Location:1119 → 1407
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038657878.1 → XP_038513806.1  ankyrin repeat and KH domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QAE5, A0A8I3MEK8, A0A8I3MI85
      Related
      ENSCAFP00845002238.1, ENSCAFT00845002815.1
      Conserved Domains (3) summary
      PHA03095
      Location:206 → 526
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:401 → 430
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:504 → 555
      Ank_2; Ankyrin repeats (3 copies)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      33125806..33244752
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      33993175..34112289
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      34746141..34864980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      32656633..32775478
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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