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    ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [ Podarcis muralis (Common wall lizard) ]

    Gene ID: 114595507, updated on 15-Mar-2024

    Summary

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    Gene symbol
    ARAP1
    Gene description
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
    See related
    Ensembl:ENSPMRG00000001406
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Podarcis muralis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Podarcis
    Orthologs
    human mouse all
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    Genomic context

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    See ARAP1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    100 current PodMur_1.0 (GCF_004329235.1) 4 NC_041315.1 (5284916..5431251)

    Chromosome 4 - NC_041315.1Genomic Context describing neighboring genes Neighboring gene myelin P2 protein pseudogene Neighboring gene StAR related lipid transfer domain containing 10 Neighboring gene fatty acid-binding protein, adipocyte-like Neighboring gene uncharacterized LOC114595508 Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene phosphodiesterase 2A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_041315.1 Chromosome 4 Reference PodMur_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Podarcis muralis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference PodMur_1.0 Primary Assembly

    Genomic

    1. NC_041315.1 Reference PodMur_1.0 Primary Assembly

      Range
      5284916..5431251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028725789.1 → XP_028581622.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:1014 → 1194
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:369 → 479
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:496 → 584
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:802 → 908
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1322 → 1449
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1230 → 1322
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:595 → 709
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:921 → 1009
      PH-like; Pleckstrin homology-like domain

    2. XM_028725785.1 → XP_028581618.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:1015 → 1195
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:370 → 480
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:497 → 585
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:803 → 909
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1323 → 1450
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1231 → 1323
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:596 → 710
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:922 → 1010
      PH-like; Pleckstrin homology-like domain

    3. XM_028725791.1 → XP_028581624.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X4

      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:997 → 1177
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:370 → 462
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:479 → 567
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:785 → 891
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1305 → 1432
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1213 → 1305
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:578 → 692
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:904 → 992
      PH-like; Pleckstrin homology-like domain

    4. XM_028725790.1 → XP_028581623.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A670HQE0
      Related
      ENSPMRP00000001913.1, ENSPMRT00000002035.1
      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:1015 → 1193
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:370 → 480
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:497 → 585
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:803 → 909
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1321 → 1448
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1229 → 1321
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:596 → 710
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:922 → 1010
      PH-like; Pleckstrin homology-like domain

    5. XM_028725792.1 → XP_028581625.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X5

      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:997 → 1175
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:370 → 462
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:479 → 567
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:785 → 891
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1303 → 1430
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1211 → 1303
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:578 → 692
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:904 → 992
      PH-like; Pleckstrin homology-like domain

    6. XM_028725786.1 → XP_028581619.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:1015 → 1195
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:370 → 480
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:497 → 585
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:803 → 909
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1323 → 1450
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1231 → 1323
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:596 → 710
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:922 → 1010
      PH-like; Pleckstrin homology-like domain

    7. XM_028725787.1 → XP_028581620.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (10) summary
      PHA03247
      Location:69 → 259
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:1015 → 1195
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:370 → 480
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:497 → 585
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:803 → 909
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1323 → 1450
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1231 → 1323
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:596 → 710
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:922 → 1010
      PH-like; Pleckstrin homology-like domain

    8. XM_028725793.1 → XP_028581626.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X6

      Conserved Domains (8) summary
      cd04385
      Location:729 → 909
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:84 → 194
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:211 → 299
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:517 → 623
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1037 → 1164
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:945 → 1037
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:310 → 424
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl17171
      Location:636 → 724
      PH-like; Pleckstrin homology-like domain

    9. XM_028725794.1 → XP_028581627.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X7

      Conserved Domains (8) summary
      cd04385
      Location:723 → 903
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:78 → 188
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:205 → 293
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:511 → 617
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1031 → 1158
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:939 → 1031
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:304 → 418
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl17171
      Location:630 → 718
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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