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    ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [ Lacerta agilis ]

    Gene ID: 117045127, updated on 19-Mar-2024

    Summary

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    Gene symbol
    ARAP1
    Gene description
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
    See related
    EnsemblRapid:ENSLAGG00000008374
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lacerta agilis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Lacerta
    Orthologs
    human mouse all
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    Genomic context

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    See ARAP1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    100 current rLacAgi1.pri (GCF_009819535.1) 4 NC_046315.1 (3515588..3626574)

    Chromosome 4 - NC_046315.1Genomic Context describing neighboring genes Neighboring gene ClpB family mitochondrial disaggregase Neighboring gene StAR related lipid transfer domain containing 10 Neighboring gene enhancer of rudimentary homolog Neighboring gene phosphodiesterase 2A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_046315.1 Chromosome 4 Reference rLacAgi1.pri Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Lacerta agilis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rLacAgi1.pri Primary Assembly

    Genomic

    1. NC_046315.1 Reference rLacAgi1.pri Primary Assembly

      Range
      3515588..3626574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033145915.1 → XP_033001806.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

      Related
      ENSLAGP00000017796.1, ENSLAGT00000019426.1
      Conserved Domains (10) summary
      PHA03247
      Location:67 → 263
      PHA03247; large tegument protein UL36; Provisional
      cd04385
      Location:1001 → 1179
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:374 → 466
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:482 → 571
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:789 → 895
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1307 → 1434
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1215 → 1307
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:582 → 696
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:4 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:908 → 996
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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