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    ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [ Ochotona curzoniae (black-lipped pika) ]

    Gene ID: 121145497, updated on 22-Mar-2024

    Summary

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    Gene symbol
    ARAP1
    Gene description
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ochotona curzoniae
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
    Orthologs
    human mouse all
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    Genomic context

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    See ARAP1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    100 current NIBS_Ocur_1.0 (GCF_017591425.1) Unplaced Scaffold NW_024467108.1 (2869669..2925272, complement)

    NW_024467108.1Genomic Context describing neighboring genes Neighboring gene T-cell ecto-ADP-ribosyltransferase 1-like Neighboring gene phosphodiesterase 2A Neighboring gene StAR related lipid transfer domain containing 10 Neighboring gene autophagy related 16 like 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024467108 Unplaced Scaffold Reference NIBS_Ocur_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ochotona curzoniae Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NIBS_Ocur_1.0 Primary Assembly

    Genomic

    1. NW_024467108.1 Reference NIBS_Ocur_1.0 Primary Assembly

      Range
      2869669..2925272 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040964391.1 → XP_040820325.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (9) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd13259
      Location:1273 → 1401
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )

    2. XM_040964389.1 → XP_040820323.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (9) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd13259
      Location:1273 → 1412
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )

    3. XM_040964393.1 → XP_040820327.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X2

      Conserved Domains (9) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd13259
      Location:1273 → 1401
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )

    4. XM_040964392.1 → XP_040820326.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (9) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd13259
      Location:1273 → 1412
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )

    5. XM_040964390.1 → XP_040820324.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1

      Conserved Domains (9) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd13259
      Location:1273 → 1412
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )

    6. XM_040964395.1 → XP_040820329.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X4

      Conserved Domains (8) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )

    7. XM_040964394.1 → XP_040820328.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X3

      Conserved Domains (8) summary
      cd04385
      Location:967 → 1145
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:339 → 430
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:446 → 535
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:753 → 858
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13257
      Location:872 → 962
      PH4_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 4
      cd17226
      Location:1181 → 1273
      RA_ARAP1; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)
      cd08837
      Location:545 → 660
      ArfGap_ARAP; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing proteins
      cl15755
      Location:6 → 68
      SAM_superfamily; SAM (Sterile alpha motif )
    Nucleotide Protein
    Heading Accession and Version

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