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Select item 50261.

Full record GDS5026

17β-estradiol effect on breast adenocarcinoma cells deficient in extracellular signal-regulated kinase 5

Analysis of MCF-7 breast cancer (BC) cells depleted for ERK5 then treated with 17β-estradiol. Increased kinase activity is associated with a poorer outcome for BC patients. Results provide insight into the interplay between estrogen receptor and protein kinase pathways to regulate BC aggressiveness

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 genotype/variation sets

Platform:: GPL96
Series:: GSE53394
8 Samples

Download data: CEL

DataSet

Accession:: GDS5026

ID:: 5026

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54032.

Full record GDS5403

Rheumatoid arthritis and osteoarthritis: synovial tissues (Jena dataset)

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 disease state sets

Platform:: GPL96
Series:: GSE55457
33 Samples

Download data: CEL

DataSet

Accession:: GDS5403

ID:: 5403

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54023.

Full record GDS5402

Rheumatoid arthritis and osteoarthritis: synovial tissues (Leipzig dataset)

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE55584
16 Samples

Download data: CEL

DataSet

Accession:: GDS5402

ID:: 5402

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54014.

Full record GDS5401

Rheumatoid arthritis and osteoarthritis: synovial tissues (Berlin dataset)

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 disease state sets

Platform:: GPL96
Series:: GSE55235
30 Samples

Download data: CEL

DataSet

Accession:: GDS5401

ID:: 5401

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54075.

Full record GDS5407

CD40 activation effect on CD19-positive B cells

Analysis of peripheral blood-purified CD19-positive B cells activated with CD40. CD40 is a potent activation stimulus for the induction of B cell-mediated antigen presentation and cytokine production. Results provide insight into molecular mechanisms underlying B cell activation via CD40.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 individual, 2 protocol sets

Platform:: GPL96
Series:: GSE54017
8 Samples

Download data: CEL

DataSet

Accession:: GDS5407

ID:: 5407

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 48446.

Full record GDS4844

Cystic fibrosis: rectal epithelia

Analysis of rectal mucosal epithelia from cystic fibrosis patients homozygous for the three-base-pair deletion c.1521_1523delCTT (p.Phe508del, F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR). Results provide insight into molecular mechanisms underlying CF.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL96
Series:: GSE15568
29 Samples

Download data: CEL

DataSet

Accession:: GDS4844

ID:: 4844

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 49957.

Full record GDS4995

Scleroderma-associated interstitial lung disease patients: pulmonary fibroblasts

Analysis of lung fibroblasts isolated from biopsies, taken at the time of diagnosis, from patients with well-defined pulmonary fibrosis associated with systemic sclerosis (SSc-ILD). Results provide insight into the molecular mechanisms underlying the fibrotic fibroblast phenotype in SSc-ILD.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 disease state sets

Platform:: GPL96
Series:: GSE40839
21 Samples

Download data: CEL

DataSet

Accession:: GDS4995

ID:: 4995

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 44188.

Full record GDS4418

Allergic asthma: bronchial biopsies

Analysis of bronchial biopsies from allergic asthma (AA) subjects. These results, together with those from GDS4417 (a study with similar specimen collection procedures, but different subjects, GeneChips, data processing), provide insight into molecular mechanisms underlying AA pathophysiology.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL96
Series:: GSE41649
8 Samples

Download data: CEL

DataSet

Accession:: GDS4418

ID:: 4418

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 45019.

Full record GDS4501

Acute myeloid leukemia with mutated nucleophosmin: bone marrow blasts (test set)

Analysis of AML blasts displaying aberrant cytoplasmic localization of nucleophosmin (NPMc+ AML) but negative for AML-associated chromosomal translocations. Results provide insight into the validity of the putative predictors of NPM status identified by the training set.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL96
Series:: GSE34860
39 Samples

Download data: CEL

DataSet

Accession:: GDS4501

ID:: 4501

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 450010.

Full record GDS4500

Acute myeloid leukemia with mutated nucleophosmin: bone marrow blasts (training set)

Analysis of AML blasts displaying aberrant cytoplasmic localization of nucleophosmin (NPMc+ AML) but negative for AML-associated chromosomal translocations. Results provide insight into putative predictors of NPM status.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL96
Series:: GSE34860
39 Samples

Download data: CEL

DataSet

Accession:: GDS4500

ID:: 4500

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 408811.

Full record GDS4088

Variable breast cancer tumor sample collection methods

Analysis of breast tumor samples preserved using 2 different RNA stabilization methods (RNAlater or snap freezing) up to 3 hours post tumor excision. Results provide insight into the effects of tissue handling on RNA integrity and microarray measurements from resected breast cancers.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 11 individual, 35 other, 2 protocol, 6 time sets

Platform:: GPL96
Series:: GSE25011
86 Samples

Download data: CEL

DataSet

Accession:: GDS4088

ID:: 4088

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 456012.

Full record GDS4560

Oral squamous cell carcinoma-derived cell lines

Analysis of oral squamous cell carcinoma (OSCC)-derived cell lines. OSCC is a lethal disease with early death typically occurring as a result of local invasion and regional lymph node metastases. Results provide insight the molecular mechanisms underlying OSCC.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 9 cell line sets

Platform:: GPL96
Series:: GSE31853
9 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4560

ID:: 4560

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 454113.

Full record GDS4541

Hungington's disease: whole blood

Analysis of whole blood from Huntington’s disease (HD) patients and age- and sex-matched healthy controls. To date, a robust and clinically useful blood test for HD has not been developed. Results provide insight into blood biomarkers for HD activity.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 12 age, 2 disease state, 2 gender, 14 individual sets

Platform:: GPL96
Series:: GSE24250
14 Samples

Download data: CEL

DataSet

Accession:: GDS4541

ID:: 4541

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 398314.

Full record GDS3983

Pancreatic beta cells and panel of primary tissues

Analysis of adult pancreatic beta cell-enriched fractions and duct cell-enriched fractions and other human primary tissues. Results provide insight into conserved beta cell markers for assessment of beta cell phenotype.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 17 tissue sets

Platform:: GPL96
Series:: GSE30803
33 Samples

Download data: CEL

DataSet

Accession:: GDS3983

ID:: 3983

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 407815.

Full record GDS4078

Acquired paclitaxel-resistant MDA-MB-231 cancer cells response to bexarotene treatment

Analysis of acquired paclitaxel (PTX)-resistant MDA-MB-231 cells treated with bexarotene-PTX or PTX. Retinoid X receptor-selective agonist bexarotene was efficacious in treating chemo-resistant cancer cells. Results provide insight into bexarotene’s role in overcoming acquired drug resistance.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 agent, 2 cell type sets

Platform:: GPL96
Series:: GSE12791
16 Samples

Download data: CEL

DataSet

Accession:: GDS4078

ID:: 4078

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 385216.

Full record GDS3852

Smooth muscle cell cord morphogenesis (HG-U133A)

Analysis of HITC6 vascular smooth muscle cells (SMC) before and after serum withdrawal-induced formation of cords showing end-to-end and side-to-side SMC assemblies that approximate the association of SMCs in the arterial media. Results provide insight into molecular basis of SMC cord morphogenesis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 time sets

Platform:: GPL96
Series:: GSE21363
6 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3852

ID:: 3852

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 420917.

Full record GDS4209

Anti-CD47 antibody dimer MABL (S-S diabody) effect on leukemia cell line: time course

Temporal analysis of MOLT-4 leukemia cells treated with 10 ug/mL anti-CD47 dimer MABL (S-S diabody). Cell surface antigen CD47 ligation induces apoptosis in B-chronic lymphocytic leukemia. Results provide insight into the molecular mechanism of CD47-mediated apoptosis in lymphoid malignant cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 time sets

Platform:: GPL96
Series:: GSE16494
10 Samples

Download data: CEL

DataSet

Accession:: GDS4209

ID:: 4209

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 451518.

Full record GDS4515

Microsatellite-unstable colorectal cancer

Analysis of colorectal adenocarcinomas with microsatellite instability (MSI CRCs). MSI, caused by defects in the mismatch repair system, is observed in a subset of CRCs. Results provide insight into molecular mechanisms contributing to MSI CRC development.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL96
Series:: GSE24514
49 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4515

ID:: 4515

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 388919.

Full record GDS3889

Hematopoietic CD34+ cells exposed in vitro to dioxin

Analysis of hematopoietic progenitor CD34+ cells from 5 healthy donors (3 paired samples) before and after in vitro 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. Results provide insight into the molecular pathways of TCDD-induced hematopoietic progenitor cell impairment in bone marrow.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 5 individual sets

Platform:: GPL96
Series:: GSE24193
8 Samples

Download data: CEL

DataSet

Accession:: GDS3889

ID:: 3889

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 405620.

Full record GDS4056

ER-positive/HER2-negative and ER-negative/HER2-negative breast cancer biopsies (USO-02103 cohort)

Analysis of pre-treatment biopsies from 62 HER2-normal breast cancer patients (ER-positive and ER-negative subtypes) from US Oncology clinical trial 02103. Results provide insight into molecular mechanisms associated with chemotherapy sensitivity in breast cancer subtypes.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 disease state, 2 genotype/variation, 2 other, 4 specimen sets

Platform:: GPL96
Series:: GSE23988
61 Samples

Download data: CEL

DataSet

Accession:: GDS4056

ID:: 4056

PubMed Similar studies GEO Profiles Analyze DataSet

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